Objective To study the effect of rehabilitation of club-based activities on the quality of postoperative life of patient with breast cancer. Methods A total of 60 patients with breast cancer were randomly divided into experiment group and control group. Conventional nursing was given to the patients in the control group after discharge, and at the same time the patients in the experiment group participated in the activities organized by the rehabilitation club for 6 months. The life quality was assessed by quality of life questionnaire-core30 (QOL-C30). Result The scores of the experiment group were significantly better than those of the control group (P<0.05). Conclusion The activities by the rehabilitation club for the patients with breast cancer can improve the patients, quality of life.

Objective To study and analyze the effects of two different routes of intravenous administration on mannitol induced phlebitis. Methods 98 patients who received mannitol infusion in the first people's hospital in Wenling from December 2013 to December 2016 were selected as the study objects. The patients were divided into PICC group and peripheral group according to different intravenous administration modes. In group PICC, 49 cases were given intravenous administration by PICC. In peripheral group, 49 cases were received peripheral vein indwelling needle. The incidence of phlebitis in the two groups was compared. Results The data showed that the incidence of phlebitis in group PICC was 8.16%, and the incidence of phlebitis in peripheral group was 22.45%. The difference between the two groups was statistically significant (P<0.05). Conclusion Mannitol infusion by PICC can reduce the incidence of phlebitis.

Objective To evaluate the usefulness of MRI in the diagnosis of adenomyosis. Methods Sagittal Turbo SE T 1WI, T 2WI, T 1SPIR and T 2SPIR MRI examination were performed on 30 cases with adenomyosis. Results The lesions in 12 cases with diffuse adenomyosis were demonstrated as diffusely thickened junctional zone (JZ) measured 10～35 mm (mean 18 mm) On T 2WI. 6 of them were of homogenous hypointensity. Another six had hyperintensive foci within the hypointensive lesions on T 2WI, and these hyperintensive foci could also be found on T 1WI in 5 lesions. 23 focal lesions (adenomyomas) in 18 cases were oval, irregular or round masses with hypointensity that were the same as the intensity of JZ on T 2WI. They were from 2.0-7.5 cm in diameter (mean 3.9 cm), and all but one showed ill-defined margins. 15 masses hadhyperintensive foci within the hypointensive lesions on T 2WI and 12 of 15 presented hyperintensity on T 1WI. The diffusely thickened JZ and focal masses correspond to the hyperplastic and hypertrophic musculature around the heterotopic endometrial islands. The hyperintensive foci were correlated with the heterotopic endometrial islands. The hyperintensive foci showed only on T 2WI corresponded to the heterotopic endometrial islands without hemorrhage. The hyperintensive foci shown on both T 2WI and T 1WI were the heterotopic endometrial islands with hemorrhage. Conclusion MRI is the modality of choice for the diagnosis of adenomyosis. T 2WI is the most useful sequence. T 2WI combining with T 1WI, T 1SPIR, and T 2SPIR can improve the accuracy in the diagnosis of adenomyosis.

Objective To explore the resistance to antibacterial drugs in Mycoplasma pneumoniae (Mp) isolated from the chil-dren with community acquired pneumonia (CAP) in Shiyan area .Methods A total of 426 throat swabs and serum samples were collected from children patients with suspected CAP in Shiyan area from Feb .2013 to Apr .2015 .The throat swabs were used to culture Mp .The serum Mp-IgM was detected by ELISA ,the positive samples were confirmed by plate culture method ,meanwhile , the drug sensitivity test was taken .Results Among 426 children cases ,69 cases were confirmed as Mp infection ;the drug suscepti-bility test results showed that the resistance rate of Mp was 76 .8(53/69) to erythromycin ,65 .2% (45/69) to azithromycin ,18 .8%(13/69) to levofloxacin ,4 .3% (3/69) to tetracycline ,4 .3% (3/69) to minocycline and 24 .6% (17/69) to gentamicin .Conclusion Mp is one of the key pathogens of CAP in Shiyan area ,which is severely resistant to macrolide .The treatment should choose sensi-tive drugs as the treatment drug ,but it is important to consider the toxicity and adverse reactions of these several kinds of drugs to children .The blind medication should be avoided .

Objective:To evaluate the value of the preoperative T staging of laryngeal and hypopharyngeal cancers by MRI at high field strength(1.5T).Methods:The MRI data of 36 cases of primary laryngeal or hypopharyngeal cancers were retrospectively staged,and compared with the clinical and postsurgical pathologic staging.Results:The accuracy of staging in each T stage of laryngeal and hypopharyngeal cancers was:T1:92%;T2:86%;T386%;T4:100% by MRI vs.T1:100%;T286%;T3:57%;T4:22% by clinic/laryngoscope.The total accuracy of MRI and clinic/laryngoscope respectively was 92% vs 69%.P＜0.05.Conclusion:MRI can correctly depict the original tumors site and invasion extension of laryngeal and hypopharyngeal cancers by comparing T1WI and T2WI with multiplanar,consequently improve the accuracy for staging significantly.

Objective Monkey B virus(BV), also known as Cercopithecine herpesvirus 1,is an important zoonotic pathogen.According to the national standard, antibodies are detected using BV as an antigen.However, the preparation of BV antigen is very stricted due to biosafety issues.Therefore, in this study, we used alternative antigens to detect the BV antibody by serological assay and verified their specifity and sensitivity.Methods A total of 135 blood samples from rhesus monkeys were tested by two ELISA method (BV and HVP2) and enzyme immunosorbent assay (EIA)method.The positive and suspicious samples were verified by immuno-fluorescence assay (IFA), Western blot and immunoblotting technique using HSV-1 gC1 purified glycoprotein as an antigen.Results The positive rates of HVP2-ELISA, BV-ELISA and HSV-1-EIA were 32.6%, 37.8% and 34.8%, respectively.Consistant result of the three detection method accounted for 91.1% (123/135), and the positive result were confirmed by IFA And WB.There were 12 suspicious samples,in which 33.3% (4/12) were verified to be positive.Conclusions Compared with BV antigen, the sensitivity and specificity of the alternative antigen HSV-1 are moe close than HVP2.Positive and suspicious samples should be verified by several method to avoid missed detection.

Objective To study the clinical values of MRI and B-ultrasonography in the diagnoses of gynecological pelvic tumors.Methods From September 2014 to September 2016,130 patients with gynecological pelvic tumors were randomly selected and examined by MRI and B-ultrasonography respectively.MRI and B-uhrasonography were compared on the misdiagnosis and missed diagnosis rate,detection rate of malignant tumor as well as diagnosis coincidence rate.Results The detection rate of malignant tumor,the misdiagnosis and missed diagnosis rate and the diagnosis coincidence rate of MRI were 96.15％,10.77％ and 89.23％ respectively,those of B-ultrasonography were 76.92％,24.62％ and 75.38％ respectively,and there were significant differences between all the rates of MRI and B-ultrasonography (P＜0.05).Conclusion MRI diagnoses pelvic tumors effectively,while behaves not so well as B-ultrasonography in cost,timeliness and scan time.

Objective To observe the effects of color retention treatment on the preservation of medicinal plant herbariums, film-cover specimens and resin specimens. Methods Seven kinds of medicinal plants with different characters after color retention treatment were made into herbariums, film-cover specimens and resin specimens, and then the preservation results for the above three kinds of medicinal plant specimens with or without color retention treatment were compared. Results Resin and film-cover specimens without color retention treatment had better preservation results than herbariums. All of the three kinds of specimens with color retention treatment had better preservation results for the original color and shape than the specimens without color retention treatment. Conclusion Color retention treatment for the medicinal plants results into higher preservation quality of the herbariums and longer preservation period.

The degranulation of mast cells represents a pivotal e-vent in the allergic disorders.The Src family kinases(SFKs)are as a starting signal in the activation of mast cell.Lyn,Fyn and Syk play important regulatory role in the degranulation of mast cells.Regulating SFKs can reduce the degranlation process and inhibit the allergic disorders.Therefore,SFKs inhibitors can be potential drugs in the allergy.It is necessary to study the targeted medicine of SFKs,which will be a new direction of drug develop-ment.

Objective To discuss the effect of pericardial devascularization plus gastric fundus transaction in advance schis?tosomiasis patients with portal hypertension. Methods Thirty?six advanced schistosomiasis patients with portal hypertension treated with devascularization plus gastric fundus transaction(a portal hypertension group),as well as 10 patients treated with modified Sugiura operation(a modified Sugiura operation group)in the Third People’s Hospital of Yangxin County since 2006 were chosen as the observation objects,and the clinical effects of the two groups were observed and compared. Results The op?eration time,indwelling time of stomach tube,time to taking food after operation,drainage tube removal time of the portal hy?pertension group were all shorten than those of the modified Sugiura operation group(all P<0.05). The hospitalization expenses of the two groups were(25 466.00 ± 2 888.48)Yuan and(34 517.10 ± 4 948.39)Yuan respectively,and the difference was al?so statistically significant(P<0.05). The incidence rates of portal thrombosis of the portal hypertension group and modified Sug?iura operation group were 33.33%(12/36)and 40.00%(4/10),respectively,and the incidence rates of rehaemorrhagia of the two groups 12 months after the operation were 16.67%(6/36)and 10.00%(1/10),respectively,but the differences had no sta?tistically significance(both P>0.05). In addition,1 case with delayed gastric emptying and 1 case with stomal leak of esopha?gus happened in the modified Sugiura operation group,while no corresponding complications happened in the portal hyperten?sion group. Conclusions Pericardial devascularization plus gastric fundus is a relatively easy procedure which has a good short?term clinical effect,and therefore it is suitable for application in primary hospitals. However,its long?term effect still needs fur?ther observation.