Objective To summarize the clinical feature and diagnosis experience of sliid pseudopapillary tumor of pancreas (SPT).Methods Clinical manifestations,laboratory examination imageology,operative procedure,pathology of 22 patients from January 2000 to December 2008 were retrospectively analyzed.Results Clinical presentation included a palpable abdominal mass in 3 cases,abdominal pain in 1 cases,abdominal distention in 5 cases,13 cases were asymptomatic.Tumor markers in all patients were negative.Abdominal imaging showed solid and solid cystic masses in pancreas or abdominal cavity.Ten cases located in the head of pancreas,8 cases in the body of pancreas,4 cases in the tail of pancreas.The correct diagnosis proportion of MRI and CT was 33.3％(2/6) and 18.2％(4/22) respectively.Conclusion SPT is one of rare pancreatic neoplasm with low malignant potential,affecting primarily young women.Typital image characteristic contributes to the diagnosis of SPT.