1.THE ROLE OF SOCIAL SCIENCE RESEARCH IN REDUCING THE BURDEN OF TUBERCULOSIS IN HIGH HIV PREVALENCE SETTINGS
Jintana Ngamvithayapong-Yanai ; Nobukatsu Ishikawa
Tropical Medicine and Health 2006;34(1):7-13
Tuberculosis (TB) is a global public health problem. The HIV⁄AIDS epidemic negatively affects tuberculosis control in many countries. The United Nations has set the Millennium Development Goals (MDGs) aiming to halve TB prevalence and mortality by the year 2015. In this paper, the authors summarize the global situation of TB associated with HIV⁄AIDS (TB⁄HIV), WHO‘s interim policy on TB⁄HIV, as well as the status and needs of social science research. The authors reviewed two major social interventions which are critical for TB control in HIV high prevalence settings, namely those to reduce stigma and those to promote adherence to TB⁄HIV medication. The review suggests that more social science research should be implemented in resource limited countries.
2.Engaging women volunteers of high socioeconomic status in supporting socioeconomically disadvantaged tuberculosis patients in Chiang Rai, Thailand
Ngamvithayapong-Yanai Jintana ; Luangjina Sarmwai ; Nedsuwan Supalert ; Kantipong Pacharee ; Wongyai Jirapohn ; Ishikawa Nobukatsu
Western Pacific Surveillance and Response 2013;4(1):34-38
Problem: The 2008 tuberculosis (TB) surveillance of Chiang Rai Hospital, Chiang Rai, Thailand reported that 8.4% of Thai, 22.7% of hill tribe minority and 25% of migrant patients (n = 736) defaulted from treatment.
Context: TB patient management in Chiang Rai is complicated due to poverty and HIV stigma. A previous study shows unaffordable travel expense was one of the reasons of patient default.
Action: We engaged Chiang Rai women’s organizations whose members are of high socioeconomic status to support poor TB patients financially and socially. A group of women formed a team to support these TB patients (n = 192) by raising and sustaining funds and providing home visits (n = 37). TB surveillance and patient-fund register data were used to evaluate TB treatment outcomes.
Outcome: The success of TB treatment was significantly higher for patients receiving financial support (relative risk [RR]: 1.351; 95% confidence interval [CI] 1.20–1.53; P < 0.000). Lower death rates in all groups were observed among patients receiving financial support. However, financial assistance alone did not improve treatment outcomes for migrant patients. Thirty-seven patients (25 Thai, eight hill tribe, four migrants) who were visited by women volunteers at home achieved 95% TB treatment success.
Discussion: It is possible to involve volunteers to support poor TB patients. Willingness to support TB patients was driven by presenting provincial TB epidemiology information, research data on the experience of poor patients and the inspiring experiences of other women volunteers. Future research should investigate the reasons for the high treatment success among patients who received home visits.
3.Characteristics and treatment outcomes of tuberculosis cases by risk groups, Japan, 2007-2010
Uchimura Kazuhiro ; Ngamvithayapong-Yanai Jintana ; Kawatsu Lisa ; Ohkado Akihiro ; Yoshiyama Takashi ; Shimouchi Akira ; Ito Kunihiko
Western Pacific Surveillance and Response 2013;4(1):11-18
Introduction: We studied the characteristics and treatment outcomes of the following risk groups for tuberculosis (TB): those with HIV and diabetes mellitus (DM), contact cases, the homeless, foreigners, health care workers (HCW) and the elderly.
Method: A descriptive cross-sectional study was conducted by analysing the Japanese TB surveillance data of all cases registered between 2007 and 2010 (N = 96 689).
Results: The annual proportion of TB cases by risk group was stable over the study period, although there was a slight but significant increase observed for foreigner and elderly cases. Homeless and elderly TB cases had the highest DM co-morbidity (16.6% and 15.3%), respectively. HIV co-infection was low in all TB cases (0.2%) yet highest in foreigners (1.3%). HIV status of 45% of TB cases was unknown. The proportion of multidrug-resistant TB (MDR-TB) was similar among all risk groups (0.0%–0.9%) except foreigner, at 3.4%. Males in most risk groups had higher mortality than females; the mortality of all TB cases in all age groups for both males and females was 3.6–24 times higher than the general population.
Discussion: Reasons for the high proportion of “HIV status unknown” should be investigated and improved. Contact tracing among foreign cases with MDR-TB should be a priority. Homeless persons should be screened for DM together with TB. Programmes to enhance health and nutrition status may benefit TB prevention among the elderly. Tuberculosis screening and TB education are important for HCW.