1.Unilateral neglect after stroke
International Journal of Cerebrovascular Diseases 2009;17(1):33-36
Unilateral neglect is one of the common advanced neurological deficits of stroke. This article highlights the post-stroke definition of unilateral neglect, incidence, sites of lesion resulting in neglect, possible mechanisms and clinical manifestation. It overviews the typing and complications of unilateral neglect, and points out that the significance on the assessment and treatment of unilateral neglect.
2.Preliminary research on dosimetry methods of 252Cf neutron after-loading radiotherapy machine
China Medical Equipment 2014;(1):11-13,14
Objective:To study the dose measurements methods of neutron andγ-ray for 252Cf neutron after-load radiotherapy machine. Methods:To measure the neutron-γmixed field with one ion chamber that have the similar sensitivities of neutron andγ-ray, another ion chamber that only have sensitivities for γ-ray, little sensitivity for neutron. Verification measurement results with calculated values. Results:Calculate key parameters, measure neutron andγ-ray dose rate at the position of 2.5cm, 5cm, 7.5cm and 10cm from the 252Cf, the Maximum deviation is-5.22%compared with calculated values. Conclusion:The method of twin ion chamber can measure the neutron andγ-ray mixed field dose.
3.Rehabilitation for Unilateral Neglect Following Stroke (review)
Chinese Journal of Rehabilitation Theory and Practice 2009;15(2):146-148
Unilateral neglect is a common and advanced nervous disorder of stroke, well-recognized predictor of poor neural functional outcome following stroke. There are several rehabilitation Methods including sensation input, visual scanning training, vestibular stimulation, head and trunk rotation, suggestive therapy, environmental adaptation and activities of daily living training, and some new therapies including prism adaptation, constraint-induced movement therapy, eye patching and transcranial magnetic stimulation developed in the past few years, which to some extent are effective on the treatment of neglect.
4.Ultrasound guided radiofrequency ablation for liver carcinoma
Xiru LI ; Qingjiu MA ; Jinsheng WU
Chinese Journal of General Surgery 2001;0(08):-
Objective To evaluate the efficacy of ultrasonically guided radiofrequency (RF) thermal ablation of hepatic carcinoma (HC) with a clustered electrode. Methods Clinical records on 245 consecutively admitted HC patients who underwent RF tissue ablation therapy were analyzed. The tumor supplying blood flow, changes of tumor size, clinical manifestation, and AFP level were analyzed. Results AFP value decreased significantly in 50% of patients one week after ablation. Tumors less than 5*!cm in diameter became avascularized 1 to 6 months after the therapy, and it was noted that all tumors shrank in size after the therapy. For tumors more than 5*!cm in diameter, RF ablation was used in conjunction with intraarterial chemotherapy and embolization. Conclusion Ultrasound guided RF thermal ablation is an effective, safe, minimally invasive technique for treating malignant hepatic tumors.
5.Comparative studies of pharmacologic effects between Famotidine, Ranitidine and Cimetidine
Xinfang LI ; Jinsheng LU ; Yuhua HUANG
Chinese Pharmacological Bulletin 1987;0(03):-
Famotidine ( Fam ) antagonized the effects of histamine on guinea pig atria and rat uteri MI vitro non-competitively,however the antagonisms of Ranitidine(Ran) and Cimetidine (Cim ) on hoistamine were competitive, their pA2 were 6. 24, 5. 16 and 4. 08 for guinea pig atria , 8. 26, 7. 22 and 6. 17 for rat uteri respectively. They reduced gastric secretion of acid and pepsin of pylorus ligated rats in dose-related manner, inhibited gastric secretion stimulated byhistamine, prevented the acute gastric lesion from stress, indomethacin and histamine, and enhanced the healing process of chronic gastirc ulcerinduced by acetic acid in rats. Moreover, Fam was much more potent than Ran (6~8 times) and Cim(30 - 40 times). Besides,Cim increased hypnotic effect of phenobartal, but Ran and Fam had no or Ittile such effects.
6.Correlation between chlamydia pneumoniae infection and acute myocardial infarction
Danan LIU ; Zuoyun HE ; Jinsheng LI
Chinese Journal of Geriatrics 2003;0(07):-
Objective To investigate the correlations between chlamydia pneumoniae (Cpn) infection and acute myocardial infarction(AMI). Methods Specific antibodies and DNA to Cpn were measured in 51 patients with AMI(AMI group),42 patients with elderly myocardial infarction (OMI group) and 31 normal controls (NC group), 33 patients(UC group)who had no angiographic evidence of coronary artery disease. Moreover,the levels of fibrinogen(Fg),6-ketoprostaglandin f1alpha(6-Keto-PGF1?),thromboxane B2(TXB2) and P-selection(GMP 140) were determined in the four groups. Results The prevalence of Cpn IgG antibody was associated with AMI(OR 3.65).Adjustment for the major cardiovascular risk factors did not attenuate this correlation(OR 3.17). Those who were Cpn positive in the AMI group had significantly higher levels of Fg,TXB2 and GMP 140, and a significantly lower level of 6-Keto-PGF1? than those who were Cpn negative in the same group.Correlation analysis revealed that the average concentration of IgG antibody to Cpn was positively associated with the levels of Fg,TXB2 and GMP140 but negatively associated with the level of 6-Keto-PGF1? in the Cpn positive patients of the AMI group. Conclusions There is a significant correlation between Cpn infection and AMI. Cpn infection is associated with the levels of Fg,TXB2, 6-Keto-PGF1? and GMP140 in plasma.
7.Regulation of microvascular endothelial barrier function: a new mechanism for neuroprotection of statins
Jingjing LI ; Hua HONG ; Jinsheng ZENG
International Journal of Cerebrovascular Diseases 2009;17(1):29-32
Statins not only reduce the incidence of ischemic stroke but also have the neuroprotective effect on ischemic stroke. Experimental studies in recent years have found that the neuroprotective effect of statins is achieved by multiple mechanisms, in which the regulation of microvascular endothelial barrier is a new mechanism. This article reviews the advances in re-search on this mechanism.
8.Relationship between Herpes simplex virus infection and acute myocardial infarction
Danan LIU ; Jinsheng LI ; Zuoyun HE
Chinese Journal of Practical Internal Medicine 2001;0(05):-
ObjectiveTo investigate the correlations between Herpes simplex virus (HSV) infection and acute myocardial infarction(AMI).MethodsSpecific antibodies and DNA to HSV-1 were measured in 51 patients with AMI(AMI group),42 patients with old myocardial infarction (OMI group) and 31 normal controls (NC group) who had no angiographic evidence of coronary artery disease.Moreover,the changes of and relationships between fibrinogen(Fg),6-Keto-prostaglandin-F 1? (6-Keto-PGF 1? ),Thromboxane B 2 (TXB 2 ),P-selection(GMP 140 ) and HSV-1 infection were determined in the three groups.ResultsThe prevalence of HSV-1IgG antibody was associated with AMI(OR4.266).Adjustment for the major cardiovascular risk factors didn't attenuate this correlation(OR3.321).Those who were HSV-1 positive in the AMI group had significantly higher levels of Fg,TXB 2 and GMP 140 and a significantly lower level of 6-Keto-PGF 1? than those who were HSV-1 negative in the same group.Correlation analysis revealed that the average concentration of IgG antibody to HSV-1 was positively associated with the levels of Fg,TXB 2 and GMP 140 but negatively associated with the level of 6-Keto-PGF 1? in the HSV-1 positive patients of the AMI group.ConclusionThere is a significant correlation between HSV-1 infection and AMI.HSV-1 infection is associated with Fg,TXB 2 ,6-Keto-PGF 1? and GMP 140 .
9.Research on quality testing for active spot scanning proton and heavy ion accelerator
Jinsheng CHENG ; Jilong YUAN ; Mingsheng LI
Chinese Journal of Radiological Medicine and Protection 2016;36(8):621-625
Objective To study the quality testing of dose delivery system of the active spot scanning proton and heavy ion accelerator,in order to provide the reference for the quality control of related equipment.Methods In the four therapy rooms,both 0.6 cc chambers and Gafchromic EBT3 films were used,respectively,to test the accelerator for dose reproducibility,dose linearity,dose stability,depth dose distribution,beam scanning position deviation and radiation field uniformity in each therapy room.Results Dose reproducibility variation coefficients are all less than 1.5%,dose linearity's maximum deviations less than 2%,dose stability's deviations less than 2%,depth dose distribution stability within 2%,beam scanning position deviation less than 1 mm,consistency of irradiation field's deviation less than 2 mm,and flatness within ± 5%.Conclusions The indicators about quality testing for the active spot scanning proton and heavy ion accelerator are all in line with the requirements of IEC standards draft.
10.Quality control research of active spot scanning proton and heavy ion accelerator's radiation field uniformity
Jilong YUAN ; Mingsheng LI ; Jinsheng CHENG
Chinese Journal of Radiological Medicine and Protection 2016;36(8):626-629
Objective To develop the method for testing the consistency of irradiation field produced by the active spot scanning proton and heavy ion accelerator.Methods Calibration of the EBT3 films were carried out with the calibrated ion beam to establish the dose calibration curve.According to the different proton and carbon ion energies (proton:94.29,150.68,212.62 McV;carbon ion:175.99,283.43,412.54 MeV/u),EBT3 films were located in the solid water phantoms in each therapy room,respectively.Finally,the irradiated EBT3 films were scanned and the radiation field size's deviation and flatness were analyzed.Results In different conditions,radiation field size's deviations were all less than 2 mm and the flatness parameters were all controlled below the 5%.Conclusions EBT3 films can be used to test the active spot scanning proton and heavy ion accelerator's radiation field uniformity.