1.An Observation on the Curative Effects in Treatment of the Bony Ankylosis of Temporo—mandibular Joint with Bone Grafts
Journal of Xi'an Jiaotong University(Medical Sciences) 1981;0(02):-
In 6 cases of bony ankylosis of temporo-mandibular joint the ribs withcastal cartilage were used to graft into the crevice of the bones after theirhaving been cut so as to form the new ones. The follow-up observation of1. 5-8 years after the operations has proved that this method is much betterthan others. The new joint formed can not only make the ascending ramusresume to the original longitude, but also show a point-facet contact. Inother words, the joint formed was similar to the normal one, and itsfunction was rather good and the curative effects proved satisfactory.Recurrence was rare and the function of the mandibular movement of theocclusion relation almost returned to normal. The paper also describes briefly some main points in regards to theoperation, reports several typical cases and puts forword the writer'sopinions for discussion.
2.A study of hepatopancreatic artery with DSA and its significance in transcatheter arterial chemoembolization of hepatocellular carcinoma
Journal of Interventional Radiology 1992;0(01):-
Objective To investigate the anatomic characteristics of hepatopancreatic artery(HPA) by DSA and its significance in preventing pancreatic complications after transcatheter arterial chemoembolization(TACE) in patients with hepatocellular carcinoma.Methods 1 000 cases of hepatic arteriograms have been retrospectively reviewed. The aberrant pancreatic arteries that originate from proper hepatic artery(PHA) and all distal intrahepatic branches to PHA were called hepatopancreatic arteries. The incidence of HPA has been summed up and its anatomic characteristics such as origine, course, branches and distribution have been described. Results Of 1000 cases, HPA were found in 16 cases(1.6%). There were 2 branches of HPA in one case and there was only one branch of HPA in other 15 cases. Altogether 17 branches of HPA were found; of which, 7 branches originated from PHA(41.2%,7/17), 6 branches arose from right hepatic artery(RHA)(35.3%,6/17) and 4 branches came from left hepatic artery(LHA)(23.5%,4/17). Conclusions HPA is a kind of rare variations of pancreatic artery. The importance to avoid embolizing HPA during TACE is preventing pancreatic complications.
3.Inhibition of Pulmonary Surfactant Function by Endotoxic Rat Plasma and Its Mechanisms
Academic Journal of Second Military Medical University 1982;0(02):-
The inhibition of bronchoalveolar surfactant function by endotoxic rat plasma was compared with that by normal rat plasma with M-8601 film balance. The results showed that endotoxic rat plasma significantly inhibited surfactant function of bronchoalveolar lavage (BAL). In the same protein concentration, the inhibition effects caused by endotoxic rat plasma were comparable with those by normal rat plasma. There were no changes of the inhibition effects after incubation of BAL with either endotoxic or normal plasma at 37℃ for 30min. These results suggest that the inhibition of surfactant function by the leakage of plasma in endotoxic lung injury is mainly due to protein components.
4.The X-ray vascular anatomy of hepatogastric arteries and their significance in transcatheter arterial chemoembolization in patients with hepatocellular carcinoma
Chinese Journal of Radiology 2000;0(12):-
Objective To study the characteristics of hepatogastric artery (HGA) with DSA and its clinical significance in transcatheter arterial chemoembolization (TACE) in patients with hepatocellular carcinoma. Methods One thousand cases of hepatic DSA arteriograms had been retrospectively reviewed. The aberrant gastrointestinal arteries that originated from proper hepatic artery (PHA) or distal intrahepatic arteries to PHA were named HGA. Furthermore, according to their different courses and distributions, HGAs were subdivided into right gastric artery (RGA), aberrant left gastric artery (AbLGA), aberrant gastroduodenal artery (AbGDA), aberrant right gastroepiploic artery (AbRGEA), superior duodenal artery (SDA) and other difficult-to-named HGA. The incidence of each of them had been summed up and their anatomic characteristics such as origin, course, branches, and distribution had been described. Results Of the 1000 cases, at least one branch of HGA was found in 740 cases (74%), and altogether there were 839 branches of HGA in them. The composition of 839 branches of HGA was as follows: 682 branches of RGA (81.29%, 682/839), 84 branches of AbLGA (10.01%, 84/839), 45 branches of SDA (5.36%, 45/839), 21 branches of AbGDA (2.50%, 21/839), 1 branch of AbRGEA (0.12%, 1/839) and 6 branches of difficult-to-named HGA (0.72%, 6/839). Of the 839 branches of HGA, 412 branches originated from PHA (49.11%, 412/839), 314 branches from left hepatic artery (LHA)(37.43%, 314/839), 98 branches from right hepatic artery (RHA)(11.68%, 98/839), and 15 branches from middle hepatic artery (MHA)(1.79%, 15/839). Conclusion HGA is a common gastrointestinal arterial variation and it is very important to be familiar with it so as to prevent the gastrointestinal complications after TACE in patients with hepatocellular carcinoma.
5.The Significance of Hepatogastric Artery in Transcatheter arterial Chemoembolization in Patients with Hepatocellular Carcinoma:to Investigate the Causes of Gastrointestinal Complications
Journal of Practical Radiology 2001;0(06):-
Objective To study the anatomic characteristics of hepatogastric artery(HGA) and its significance in preventing gastrointestinal complications in patients with hepatocellular carcinoma after transcatheter arterial chemoembolization(TACE).Methods 1000 cases of hepatic arteriograms were retrospectively reviewed,the aberrant gastrointestinal arteries that originate from proper hepatic artery(PHA)and distal intrahepatic arteries to PHA were named HGA.The frequency,origine,course and distribution of all of HGAs were carefully analyzed.The trial group consists of 34 cases(42 times of TACE)who had HGA and controlled group consists 32 cases(56 times of TACE)who had no HGA.The incidence of gastrointestinal complications after TACE between two groups were compared.Within trial group,superselective catheterization was made and had the tip of catheter away from orifice of the HGA before infusion of embolic agents(Lipiodol)during TACE in 18 times,which was called relative safety group;whereas,the tip of catheter was not laid distal to orifice of HGA when infused Lipiodol through catheter in 24 times,which was called dangerous group.The incidence of complications between this two groups was also compared.Results Of 1000 cases of hepatic arteriography,HGA was found in 740 cases (74%).The incidence of gastrointestinal complication and its grave degree in trial group were more excessive than that in controlled group((?=0.004),similarly,the frequency of gastrointestinal complication and its graveness in dangerous group exceeded significantly that in relative safety group((?=0.000).Conclusion HGA is common vascular variation.That embolic agents (Lipiodol)was perfused carelessly into HGA may induced occurrence of gastrointestinal complications in patients after TACE,and having the tip of catheter away from the orifice of HGA by superselective catheterization during TACE could efficiently prevent happening of this kind of complications after operation.
6.Inhibitory Effect of Antibody Against Basic Fibroblast Growth Factor on Androgen or Glucocorticoid-induced Growth of Shionogi Carcinoma 115 Cells
Chinese Journal of Cancer Biotherapy 1994;0(01):-
The effects of androgen and glucocorticoid on the proliferation of SC-3 mouse breast carcinoma cells and their mechanisms were investigated in a serum-free culture. Both physiological concentrations of testosterone ( T) and pharmacological concentrations of dexamethasone ( Dex) significantly increased the cell proliferation. The growth-stimulatory effects of two hormones were mediated through their own receptors.SC-3 cells stimulated by T and Dex were also found to secrete fibroblast growth factor (FGF) like factor into conditioned medium (CM) . The addition of anti-FGF antibody in the medium inhibited T, Dex and bFGF-induced proliferation of SC-3 cells. Furthermore, the presence of FGF receptors in SC-3 cells were demonstrated. These results indicated that androgen and glucocorticoid-in-duced enhancement of SC-3 cell growth is mediated through an induction of FGF-like growth factor which acts on SC-3 cells as an autocrine growth factor.
7.Laparoscopic Splenic Artery Ligation in the Treatment of Hypersplenism and Thrombocytopenia in Children
Jinshan ZHANG ; Long LI ; Qi LI
Chinese Journal of Minimally Invasive Surgery 2015;(12):1075-1079
Objective To investigate the effectiveness and feasibility of laparoscopic splenic artery ligation in the treatment of hypersplenism and thrombocytopenia in children. Methods From August 2014 to December 2014, four children with hypersplenism and three children with ITP (idiopathic thrombocytopenic purpura) were treated in our hospital.Laparoscopic splenic artery ligation was performed in all the patients.During the operation, the gastric colon ligament was cut with an ultrasonic knife, and the gastric wall was suspended to expose the pancreas and the spleen.The splenic artery was ligated at the upper edge of pancreas closing to the splenic hilum.The splenic venous branches were dissected and ligated at the splenic hilum by using the Hem-o-lok, which leaded to an area of splenic infarction more than 50%. Results The laparoscopic splenic artery ligation was successfully performed in all the patients, without conversion to open surgery.The operative time was 120-150 min ( mean, 126 min) , and the intraoperative blood loss was 10-20 ml ( mean, 15 ml) .No patient underwent blood transfusion.The length of postoperative hospital stay varied from 4 to 11 days (mean, 6.6 days).The splenic length significantly decreased postoperatively [(13.6 ±2.6) cm vs.(15.1 ±1.7) cm, t=3.199, P=0.049], and so was the splenic thickness [(3.8 ±1.0) cm vs.(4.1 ±0.8) cm, t =3.703, P=0.034].Partial splenic infarction and decreased splenic blood flow were found in the 7 patients by postoperative ultrasound.After surgery, four children suffered from fever, which were 38.8 ℃, 39.0 ℃, 38.6 ℃, and 39.2 ℃, with the duration of fever of 2, 4, 8, and 5 days, respectively.All the patients were followed-up for 6 -10 months (mean, 8.4 months).The complete blood cell count was within normal range. Conclusion The laparoscopic splenic artery ligation is an effective treatment for hypersplenism and thrombocytopenia in children.
8.Clinical Application of ~(99m)Tc-Octreotide and ~(99m)Tc-MIBI Imaging in the Diagnosis of Breast Cancer
Nianying DENG ; Jinshan ZHANG ; Youqing XIAN
Chinese Journal of Bases and Clinics in General Surgery 2004;0(01):-
Objective To evaluate the value of 99mTc-Octreotide somatostatin receptor and 99mTc-MIBI imaging in the detection of breast cancer. Methods 99mTc-Octreotide and 99mTc-MIBI imaging were performed in 26 patients with breast masses before operation. The scintigraphy results were analysed compared with pathologic study.Results The sensitivity, specificity and accuracy of 99mTc-Octreotide scintigraphy for breast cancer were 94.4%, 87.5%and 92.3%respectively and those of 99mTc-MIBI were 88.9%, 75.0%and 84.6%respectively. Significant difference was found between 99mTc-Octreotide and 99mTc-MIBI in both of specificity and accuracy (P
9.Study of using urokinase for injection to lysis endometriosis ovarian cyst under sonography guided puncture
Jing ZHANG ; Jinshan GAO ; Junyan WANG
Chinese Journal of Ultrasonography 2003;0(11):-
Objective To establish a method for lysis coagula rapidly within endometriosis cyst to ease aspiration difficulty while ultrasound-guided puncture and aspiration therapy. Methods Urokinase for injection with different concentration was used to lysis the coagula within endometriosis ovarian cyst with thick content. The effect of urokinase on the coagula, the wall of cyst and the aspiration rate of content were investigated. Results The area of coagula in unit area was significantly small in urokinase group compared with that in control group[( 95.6? 17.5)?m2 vs ( 1692.3? 1028.3)?m2,F= 28.86,P= 0.000]. Urokinase can lysis the coagula appending to the wall but did not change the permeability of cyst wall. The aspiration rate was significantly faster in urokinase group than in control group[( 2.79? 2.61)ml/min vs ( 1.42? 0.58)ml/min; t= 2.4572,P= 0.0121]. Conclusions Urokinase can resolve the coagula within endometriosis ovarian cyst and on the cyst wall safely and effectively, making it easy for cyst content aspirating and improving the coagulation effect of ethanol.
10.Collective Review of55ADRs Induced by Houttuynia Cordata Injection
Yong ZHANG ; Jinshan CHEN ; Huili HUANG
China Pharmacy 1991;0(05):-
OBJECTIVE:To study the general pattern and characteristics of the ADRs associated with Houttuynia cordata injection(HCI).METHODS:An analysis was conducted on55cases of ADRs induced by HCI reported in domestic medical jou_ rnals in recent years.RESULTS:The ADRs of HCI were not related to the dosage given.The onset of ADRs was commonly within30min during infusion.The ADRs mostly occurred in groups of patients under age20and from30to59years of age.The ADRs could involve multiple organs and systems,and the clinical manifestations were varying,of which allergic reaction was the commonest one including anaphylactic shock.CONCLUSION:The mechanism of allergic reaction induced by HCI remains to be further studied.Clinical physicians,nurses and pharmacists should pay more attention to the ADRs of HCI.