Objective To explore the current status of job burnout and its influence on the nursing staffs in a third-grade class-A psychiatric hospitals in order to provide basic data for intervention .Methods A total of 121 nurses were investigated with the Chinese version of the Nurse Burnout Scale ( NBS) .Results The participants had a certain degree of burnout , of which 57.9%nurses were without or with mild burnout;36.4%nurses had mild to moderate burnout;5.8% nurses had severe burnout . One-way analysis of variance (ANOVA) showed that nursing staffs had statistical differences in marital status , education, tenure, income, department and night shifts and other dimensions of burnout (P<0.05).Multiple linear regression analysis showed that the main factors of burnout were tenure and working department , with a total contribution rate of 19.81%.Conclusions There are different levels of job burnout in psychiatric nurses , hospital administrators should take the necessary response to its targeted interventions .

Objective To explore the effects of self-role recognition nursing on the agitation behavior and social interaction in schizophrenic patients with diabetes mellitus. Methods A total of 98 cases of schizophrenia patients with diabetes mellitus treated in Wuxi Mental Health Center of Jiangsu Province from October 2014 to October 2016 were selected as the research objects. The patients were randomly divided into control group and study group by random number table method. The control group was given routine nursing intervention, while the study group was given self-role recognition nursing intervention for 6 months. The level of fasting blood glucose and 2-hour postprandial blood glucose were compared between the two groups. Patients' agitation behavior was evaluated by Cohen-Mansfield agitation inventory (CMAI); social communication ability was evaluated by social skills checklist (SSC) and social adaptive functioning evaluation (SAFE); mental status was evaluated by positive and negative syndrome scale (PANSS). The data of this study were statistically analyzed with SPSS 19.0 statistical software, in which the measurement data were tested by t-test, and the enumeration data were tested by χ2test. Results Before intervention, there was no significant difference in fasting blood glucose and 2-hour postprandial blood glucose between the two groups (P> 0.05). After intervention, the fasting blood glucose and 2-hour postprandial blood glucose level in the study group were significantly lower than those in the control group, and the differences were statistically significant (P< 0.01). The scores of physically aggressive agitation, physically non-aggressive agitation, verbal agitation and the total score of CMAI in the control group were (16.4±3.7), (31.5±4.9), (25.2±4.5), (73.1±4.5) respectively after intervention, and the scores were (11.8±3.2), (24.1±5.3), (17.5±4.2), (53.4±4.7) in the study group. The differences between the two groups after intervention were statistically significant (t=7.268, 8.617, 8.561, 15.341;P<0.01). The results of SSC scale and SAFE scale in both groups decreased than before intervention, and the scores of the study group were all lower than those of the control group, with statistical significance (P<0.01). After intervention, the scores of positive symptoms, negative symptoms, negative symptoms and the total score of PANSS scale of the study group were significantly lower than those of the control group, and the differences were statistically significant (P<0.01). Conclusions Self-role recognition nursing intervention can be used to improve the patients' social interaction ability and mental status in the nursing process of schizophrenia patients with diabetes mellitus, and it is worthy of clinical promotion.

Objective To investigate the methods and effect of specialized and standardized training, and provide evidence for the revision of the standardized training program.Methods Cluster sampling method was used to recruit all the psychiatric nurses who started their career in 2013 by“needs-based and tutorial manner”cultivating model. These nurses received a three-year standardized training. Competency inventory for registered nurse(CIRN)were used to evaluate the effect of the training program before and after the intervention. Results After three-year standardized training,the total score of CIRN was improved from(114.34±17.12) points to(147.37±14.87)points(t=-21.176,P<0.01). The dimension score of critical thinking/scientific research,clinical care,leadership ability,interpersonal relationship,legal/ethical practice,professional development and education/consultation were respectively(22.60±5.38),(17.46±3.49),(29.09±2.79), (23.69±3.00),(24.29±3.75),(12.74±2.65),(17.51±4.27)after the training,and they were all higher than (14.09±5.14),(10.11±3.21),(27.80±3.54),(22.29±3.03),(23.17±3.670),(8.54±4.50),(8.34±2.81) before the training(t=-13.896,-15.960,-3.277,-3.790,-3.545,-7.727,-14.192;P<0.01).Conclusions “Needs-based,tutorial manner”standardized training model has a positive effect on improving the core competence of new mental health nurses.

Objective:To explore the relation of self-injury behavior to thyroid hormones and lipids in adoles-cent patients with depression.Methods:A total of 182 adolescent inpatients who met the diagnostic criteria for de-pression according to the Diagnostic and Statistical Manual of Mental Disorders,Fifth Edition(DSM-5)were en-rolled,including 38 cases with self-injurious behavior and 144 cases without self-injurious.The differences in vari-ous indicators between the two groups were compared,and logistic regression analysis was used to analyze factors related to self-injury in adolescents with depression.Results:The patients with self-injurious behavior had higher levels of total cholesterol and high-density lipoprotein cholesterol(HDL-C)compared to those without self-injuri-ous behavior(P＜0.05).They also had lower levels of free thyroxine compared to the group without self-injurious behavior(P＜0.05).Logistic regression analysis results showed that those with longer duration of disease(OR=1.03)and higher HDL-C levels(OR=12.75)were more likely to have self-injurious behaviors.Conclusion:Long duration of disease and high level of HDL-C may be risk factors for self-injurious behavior in adolescents with de-pression,while low level of free thyroxine may serve as a protective factor.

Although chromosomal mosaic embryos detected by trophectoderm(TE)biopsy offer healthy embryos available for transfer,high-resolution postnatal karyotyping and chromosome testing of the transferred embryos are insufficient.Here,we applied single-cell multi-omics sequenc-ing for seven infants with blastula chromosomal mosaicism detected by TE biopsy.The chromo-some ploidy was examined by single-cell genome analysis,with the cellular identity being identified by single-cell transcriptome analysis.A total of 1616 peripheral leukocytes from seven infants with embryonic chromosomal mosaicism and three control ones with euploid TE biopsy were analyzed.A small number of blood cells showed copy number alterations(CNAs)on seem-ingly random locations at a frequency of 0％-2.5％per infant.However,none of the cells showed CNAs that were the same as those of the corresponding TE biopsies.The blastula chromosomal mosaicism may be fully self-corrected,probably through the selective loss of the aneuploid cells dur-ing development,and the transferred embryos can be born as euploid infants without mosaic CNAs corresponding to the TE biopsies.The results provide a new reference for the evaluations of trans-ferring chromosomal mosaic embryos in certain situations.