1.The clinical significance of blood relevant parameters in psoriasis vulgaris
Dengmei XIA ; Jixiang XU ; Jinnan CHENG ; Xia XIONG
The Journal of Practical Medicine 2017;33(24):4061-4064
Objective To investigate the characteristics and the clinical significance of relevant parame-ters of blood in psoriasis vulgaris(PV). Methods A retrospective analysis among 38 PV patients and 40 normal controls was done. The comparing parameters contained NLR,CRP,total cholesterol,triglyceride,serum uric acid.Pearson correlation analysis was used to detect the correlations.Results NLR,total cholesterol,triglyceride, serum uric acid in psoriasis vulgaris patients were significantly higher than in the normal controls(P < 0.05). There was a statistically significant correlation between NLR and PASI in the PV patients,but no correlation of CRP with NLR and PASI(P > 0.05). In the patients with PASI ≥ 7,the serum uric acid level was significantly higher than in those with PASI < 7. Conclusions NLR is indicateive of the severity and state of inflammation. The severer PV,the higher the level of serum uric acid.
2.Protective effect of low-level laser irradiation on lipopolysaccharide-mediated inflammatory injury of human periodontal ligament fibroblasts.
Xiao-Lan JIN ; Ya-Nan ZHANG ; Cheng-Rui SUN ; Zhao-Hui ZOU
West China Journal of Stomatology 2021;39(3):260-266
OBJECTIVES:
To study the effect and mechanism of low-level laser irradiation (LLLI) on lipopolysaccharide (LPS)-induced inflammatory injury of human periodontal ligament fibroblasts (hPDLFs).
METHODS:
hPDLFs were inoculated into well plates and randomly divided into the normal group, LPS group, and LPS+LLLI group. The cells in the normal group were cultured in conventional medium. The hPDLFs in the LPS and LPS+LLLI groups were cultured in RPMI1640 medium containing 1 mg·L
RESULTS:
Compared with the normal group, the LPS group showed increased apoptosis rate of hPDLFs and intracellular free Ca
CONCLUSIONS
LLLI has a protective effect on the inflammatory injury of hPDLFs induced by LPS, and the effect is most obvious when the irradiation intensity is 4 J·cm
Cells, Cultured
;
Fibroblasts
;
Humans
;
Interleukin-1beta
;
Lasers
;
Lipopolysaccharides
;
Periodontal Ligament
;
Tumor Necrosis Factor-alpha
3.Discussion on the theory of
Chun-Chun YAN ; Dan MENG ; Xue-Cheng ZHANG ; Yi-Fei MAO ; Hong-Ling JIA ; Yong-Chen ZHANG
Chinese Acupuncture & Moxibustion 2021;41(8):928-932
By collecting and analyzing the explanation/conception, acupoint name, acupoint location, indications, acupuncture and moxibustion techniques and contraindications of
Acupuncture
;
Acupuncture Points
;
Acupuncture Therapy
;
Humans
;
Meridians
;
Moxibustion