1.CT diagnosis and differential diagnosis of renal and retroperitoneal tumors in children
Journal of Third Military Medical University 1983;0(04):-
Objective To investigate the diagnosis and differential diagnosis of renal and retroperitoneal tumors in children with CT.Methods CT findings in 189 cases of pathologically confirmed renal and retroperitoneal tumors,including nephroblastoma in 71 cases,neurogenic tumor in 89 cases(neuroblastoma in 70 cases,ganglioneuroblastoma in 2 cases and ganglioneuroma in 17 cases),teratoma in 18 cases and lymphoma in 11 cases,were retrospectively analyzed.Results CT showed that nephroblastoma was a round or oval encapsuled mass usually resulting in renal destruction,the residual kidney was a crescent-shaped encapsuled mass which is easy to lead to thrombosis of renal vein and inferior vena cava due to tumor.The manifestations of neuroblastoma were similar to those of ganglioneuroblastoma,usually with calcification and embed vessels,and could invade the kidneys and often metastasize to lymph nodes,cranium and brain,bones and liver.The ganglioneuroma was manifested as a small oval-shaped low dense mass in adrenal gland area or in paravertebral, with no exacerbation or slight exacerbation in its early stage.Lymphoma was located around the median line and presented as an irregular mass fused by multiple lymph nodes embedding the vessels loosely.Teratoma,usually occurred on one side of the retroperitonium,was characterized by calcification/ossification and fat tissue.Conclusion CT is of a higher value for the diagnosis and differential diagnosis of renal and retroperitoneal tumors in children.
2.Influence of therapeutic communication system on depression emotion of postoperative tumor patients undergoing chemotherapy
Jinhua ZHENG ; Cuiling ZHENG ; Hongping GUO
Chinese Journal of Practical Nursing 2012;28(20):5-8
Objective To investigate the effect of therapeutic communication system on alleviation of depression emotion of postoperative tumor patients undergoing chemotherapy.Methods 56 cases of cancer patients undergoing chemotherapy after surgery were randomly divided into the observation group and the control group with 28 cases in each group.The observation group was given therapeutic communication system based on routine care,the control group only received routine care.The self-rating depression scale (SDS),automatic thoughts questionnaire (ATQ) and quality of life evaluation questionnaire (QLQ-C30 3.0) were used for evaluation in two groups before and after intervention.Results The depression mood,negative automatic thoughts and quality of life in the observation group were better than the control group,the difference was statistically significant.Conclusions Application of therapeutic communication system on postoperative tumor patients undergoing chemotherapy can alleviate depression,negative automatic thoughts and quality of life significantly.It implies the effectiveness and feasibility of psychological intervention for postoperative tumor patients undergoing chemotherapy,which is worthy of clinical application.
3.Study on acceptability of interactive teaching mode
Jinhua BAO ; Zhili ZHENG ; Hao CHEN
Chinese Journal of Medical Education Research 2012;11(10):1085-1088
Objective To probe into the optometry students' acceptability of interactive teaching mode by the questionnaire survey.Methods Totally 207 optometry students including 42 five-year undergraduate students,17 seven-year program students,95 three-year postgraduate students and 53 three-year junior college students were investigated for their acceptability of interactive teaching mode by the questionnaire survey.Results The results showed that 63.3% of the students preferred traditional teaching mode; 70% of the students would like to accept interactive teaching mode,the others didn't accept it or hesitated to accept it.Lack of self-confidence was the major reason.Conclusions Most medical college students are willing to accept the interactive teaching mode.Interactive teaching mode should be combined with traditional teaching mode.
4.Clinical analysis of laparoscopic resection for large volume of adrenal tumor in 39 cases
Guisong GAO ; Jinhua ZHENG ; Yuming ZHANG
Chinese Journal of Postgraduates of Medicine 2015;38(7):469-471
Objective To explore the clinical efficacy of laparoscopic resection for large volume of adrenal tumor.Methods Eighty patients with adrenal tumor who were treatment by laparoscopic resection were divided into large volume group (diameter ≥ 6 cm) and small volume group (diameter < 6 cm) according to the size of the tumor.The intraoperative and postoperative complications of the two groups were compared.Results The operation time,intraoperative bleeding volume and postoperative hospitalization time of large volume group were significantly higher than those in small volume group:(187.4 ±39.2) min vs.(153.7 ± 31.6) min,(458.2 ± 87.3) ml vs.(105.9 ± 25.1) ml and (10.9 ± 2.7) d vs.(7.3 ± 1.5) d,and the difference were statistically significant (P < 0.05).The postoperative complications in two groups had no significant difference:10.3% (4/39) vs.7.3% (3/41),P > 0.05.Conclusion The laparoscopic resection for large volume of adrenal tumor have the advantages of less invasion,faster recovery and less complications,and it has become the main mode of treatment.
5.Detection of human cytomegalovirus in patients with atherosclerosis and its clinical significance
Hongping GUO ; Shuhui WANG ; Jinhua ZHENG
Chinese Journal of Postgraduates of Medicine 2013;(10):11-13
Objective To investigate the infection of human cytomegalovirus (HCMV) in patients with atherosclerosis and explore its clinical significance.Methods A total of 134 patients with atherosclerosis (observation group) including 102 patients with coronary heart disease (CHD) and 32 patients with non-CHD from December 2009 to April 2012 were enrolled in this study.The 102 patients with CHD were divided into HCMV infection group (86 cases) and non-HCMV infection group (16 cases).Another 40 healthy person were selected as control group.The carotid intima-media thickness (IMT) was assessed by ultrasonography.The serum HCMV-IgM was measured by enzyme-linked immunosorbent assay.Results The infection rate of HCMV in observation group was 77.6% (104/134),which was higher than that of 37.5%(15/40) in control group(P < 0.05).The infection rate of HCMV in CHD patients and non-CHD patients was 84.3%(86/102) and 56.2%(18/32),and there was significant difference (P < 0.05).The carotid IMT in HCMV infected atherosclerosis patients was (1.31 + 0.28) mm,which was higher than that of (1.14 ± 0.21)mm in non-HCMV infected atherosclerosis patients (P < 0.05).The incidence of myocardial infarction and multi-vessel lesion in HCMV infection group was higher than that in non-HCMV infection group [39.5%(34/86) vs.25.0%(4/16) and 43.0%(37/86) vs.18.8%(3/16)](P< 0.05).The incidence of stable angina pectoris and single-vessel lesion in HCMV infection group was lower than that in non-HCMV infection group [26.7%(23/86) vs.43.8%(7/16) and 22.1%(19/86) vs.56.2%(9/16)](P<0.05).Conclusion The high-infection rate of HCMV is found in atherosclerosis patients,and it maybe have a close relationship with the occurrence and development of atherosclerosis.
6.The study of childhood trauma experience and family environment with obsession
Huirong ZHENG ; Jinhua FU ; Lingjiang LI
Chinese Journal of Behavioral Medicine and Brain Science 2008;17(11):1004-1006
Objective This study aimed to explore the relationship between the traumatic experience in childhood and onset of obsession in adulthood,and the character of family environment of obsession patients.Methods Using Y-BOCS and CAT and FES-CV to evaluate 41 cases with OCD and 36 normal subjects respectively.Baaed on these scales,an edited interview schema for a semi-structured interview was choosed with both groups for 50 minutes respectively.Results ①Tbe whole score and scores of two subscales on punishment,negative-environment in CAT were all obviously higher in patients with obsession [(50.16± 21.03),(12.03±4.24),(19.77±9.74),for punishment:P<0.05,for others:P<0.01],and there were a significant difference in the two groups[(35.35±14.78),(9.92±2.51),(12.54±8.14)].The negative environment was chosen in regress equation,and could explain 14.67% of outcome of obsession. ②The scores of 4 ubacaies like cohesion,expressiveness,intellectual-cultural orientation,active-recreational orientation [(5.13±2.28),(4.10±2.12),(2.71±1.87),(2.52±2.34)] ,were all obviously lower than the normal control in FES-CV.While the subscore of conflict (5.03±2.21) was higher than the normal control(3.50±2.40),and all these differences were significant.When two factors of active-recreational orientation and cohesion in FES-CV were put into regression equation( R2 =0.2078 ,R2 =0.2784),they contribute 27.84% and the disease,and the active-recreational orientation factor can explain 20.78%.③The result of interview found significant difference between obsession groupand control group in parental personality,own personality,childhood experience,and family environment.Condusion The traumatic experience in childhood and unhealthy family environment do have association with onset and development of obsession,also they have a close relationship with the development of personality after adulthood.
7.Participation of Anticoagulant Professional Pharmacist in the Medication for a Pulmonary Embolism Pa-tient with Warfarin Resistance
Zheng DING ; Shanshan HONG ; Jinhua ZHANG
China Pharmacist 2016;19(2):322-324
Objective: To discuss the therapeutic regimen for warfarin resistant patients with the help of clinical pharmacists. Methods:The pharmacist analyzed the cause of warfarin resistance and provided the dose adjustment for a pulmonary embolism pa-tient. Results:The genotype of the patient was identified as VKORC1-1639AG by gene test. The patient was diagnosed as hereditary warfarin resistance excluding other causes. With the assistance of pharmacist, the problem of warfarin resistant was solved. Conclu-sion:For warfarin resistant patients, clinical pharmacists must definite the reason of warfarin resistant firstly and then carry out the therapeutic strategy. Gene detection may be used as an important guide for warfarin resistance.
8.Infantile Septicemia Induced by Coagulase Negative Staphylococcus
Sumei WU ; Jinhua MENG ; Yanling ZHENG
Chinese Journal of Nosocomiology 2004;0(10):-
OBJECTIVE To investigate the major pathogenic bacteria and drug resistance in the infantile septicemia and to provide laboratory evidence for clinical diagnosis and treatment. METHODS The venous blood plate was used. RESULTS Totally 328 isolated strains were assayed with French Bio-Merieux API System.Of them,203 strains of coagulase negative Staphylococcus(CNS),being 61.9%.115 strains(56.6%) were(S.epidermidis).45 strains(22.1%) were S.haemolyticus,and 43 strains(21.1%) were S.lugdunensis.The isolated rate of meticillin resistant coagulase negative Staphylococcus(MRCNS) was 35.5%.The drug test for MRCNS showed multiple drug-resistance. CONCLUSIONS MRCNS is the major pathogen in infantile septicemia.The detectable rate of MRCNS is high.Glycopeptide antibiotics are the first-choice drugs for MRCNS infection.
9.The mRNA expression of CC chemokines in peripheral blood mononuclear cells from patients with chronic urticaria
Hui TANG ; Jinhua XU ; Zhizhong ZHENG
Chinese Journal of Dermatology 1994;0(02):-
Objective To investigate the mRNA expression of CC Chemokines, including RANTES (regulated upon activation, normal T cell expressed and secreted), monocyte chemoattracctant protein-1 (MCP-1), monocyte chemoattracctant protein-3 (MCP-3) and macrophage inhibitory protein 1? (MIP-1?), in peripheral blood mononuclear cells (PBMCs) of patients with chronic urticaria, their mutual correlation, and the relationship between the expression level of CC chemokines and the serum level of IgE and eosinophil cationic protein (ECP) in the patients. Methods Reverse transcription-polymerase reaction (RT-PCR) was applied to semiquantitatively analyze the mRNA expression of RANTES, MCP-1, MCP-3 and MIP-1? in PBMCs from 31 patients with chronic urticaria and 22 healthy subjects. Results The mRNA expression of RANTES, MCP-1, MCP-3 and MIP-1?was significantly higher in the patients than those in the normal controls (P 0.05). In the patients, the mRNA expression of RANTES negatively correlated with the serum level of IgE and ECP (P
10.Reflections on purchasing hospital library books and periodicals via bidding
Jinhua ZHENG ; Li LI ; Xia SONG
Chinese Journal of Hospital Administration 1996;0(10):-
That hospital libraries purchase books and periodicals via bidding is necessitated by social development and is characterized by the following advantages: smashing monopoly operations and adopting competitive mechanisms; reducing intermediate links and speeding up the delivery of books and periodicals; avoiding missing issues of periodicals and ensuring the completeness of periodicals; bettering preferential treatment and saving funds; standardizing market competition and reducing job-related offenses; safeguarding the legitimate rights and interests of the libraries.