1.Determination of 39 Polybrominated Diphenyl Ethers in Coastal Sediments by Ultrasonic Extraction Coupled with Gas Chromatography-Mass Spectrometry
Chinese Journal of Analytical Chemistry 2009;37(11):1627-1632
A method was developed for the determination of 39 polybrominated diphenyl ethers(PBDEs) from mono- to hepta-brominated in coastal sediment by gas chromatography/mass spectrometry. The sample was extracted with a solution of dichloromethane: n-hexane( 1:1,V/V) ,followed by ultrasonic extraction for 60 min at 25℃. The clean-up step was optimized using silica gel and alumina. The detection limit of the method was in the range of 0.003 - 0.10μg/kg. The results indicate that the average recovery of the internal standard was from 66.2% to 118. 6%. The relative standard deviation RSD( % ) was from 0. 8 % to 18. 2%. The method for the detection of 39 PBDE congeners in coastal sediment was sensitive,high reproducible with satisfactory recoveries.
2.The influence of injection rate and time resolution on dynamic contrast-enhanced MR imaging of glioma
Journal of Practical Radiology 2016;(2):292-294,304
Objective To explore the influence of contrast agent injection rate and sequence time resolution on the dynamic contrast-enhanced MR iamging of brain glioma.Methods Fifty eight cases with suspected cerebral glioma were scanned on a Verio 3.0T MRI with the regular head sequences and DCE sequences.All the cases were divided into two groups.There were 41 cases in the regular group in which the injection rate was 3 mL/s and the time resolution was above 5.36 s.Another 1 7 cases were in the optimal group in which the injection rate was 4 mL/s and the time resolution was about 4 s.The DCE images of two groups were Postprocessed by the Tofts model analysis.The curve shape of AIF were evaluated and divided in to the excellent or the secondary level.Chi-square test was used to compare the results of two groups.Results The curve shape of optimal group was much better than that of regular group(P<0.05).Conclusion Speeding up the injection rate and the time resolution of DCE sequences would improve the image quality of DCE MRI of glioma.
4.Voluntary blood donation intention of students in middle vocational school in Jinhua and its influencing factors
Xiaoyi YING ; Shufang HONG ; Zhihui WU ; Xiaoming DU ; Shuanghong LAI ; Yufan CHEN ; Xun YU
Chinese Journal of Blood Transfusion 2023;36(3):257-260
【Objective】 To explore the intention of voluntary blood donation in students from a middle vocational school in Jinhua and its influencing factors. 【Methods】 A total of 400 students were enrolled from a middle vocational school in Jinhua by convenience sampling, and a self-designed questionnaire was issued to each student to investigate the cognition, intention and attitude of voluntary blood donation. The influencing factors of voluntary blood donation intention were analyzed by Logistic regression. 【Results】 A total of 394 valid questionnaires(98.50%) were collected. For 394 surveyed students, the average score of cognition of voluntary blood donation was (7.27±2.69) points, and the overall rate of intention to voluntary blood donation was 21.32%. Logistic regression analysis equation consisted of family support, better cognition, feeling happy about blood donation and worrying about blood donation, with risk ratios(OR) as 31.78, 188.69, 26.27 and 0.01, respectively(all P<0.05). 【Conclusion】 Students from a middle vocational school showed poor congnition and intention of voluntary blood donation.Family support for voluntary blood donation, better cognition of voluntary blood donation and happiness for blood donation were positive factors, and the fear of blood donation was a negative factor.It is necessary to strengthen the publicity of blood donation among students in middle vocational school to improve their congnition and intention to voluntary blood donation.
5.Effects of ramipril on nitric oxide concentration and endothelial nitric oxide synthase activation in lung of rats with pulmonary arterial hypertension induced by monocrotaline
Jinhua SUN ; Lixing CHEN ; Lanfang CHEN
Medical Journal of Chinese People's Liberation Army 1983;0(05):-
Objective To investigate the effects of ramipril on nitric oxide(NO) concentration and endothelial nitric oxide synthase(eNOS) activation in lung of rats with pulmonary arterial hypertension induced by monocrotaline(MCT).Methods Sixty Sprague-Dawley rats were randomly divided into three groups: normal control group,MCT group and ramipril group.Rats in MCT group and ramipril group were subcutaneously injected with 60mg/kg of MCT.Then the rats in ramipril group received ramipril gavage and rats in MCT group received normal saline gavage for 4 weeks,respectively.Rats in control group were subcutaneously injected with normal saline first and then received normal saline gavage for 4 weeks.Right ventricular systolic pressure(RVSP) and right ventricle hypertrophy index(RVHI) were measured.The ratio of arteriol wall thickness/vascular external diameter(WT%) and wall area percentage(WA%) were evaluated.NO concentration in lung was determined.eNOS,P-Ser1177-eNOS and Akt phosphorylation were analyzed by Western blotting.Results The RVSP,RVHI,WT%,WA% were significantly increased,and NO concentration,the level of eNOS,P-Ser1177-eNOS,the state of Akt phosphorylation were significantly decreased in MCT group compared with that in control group(P
6.CLINICAL VALUE OF PULSE AND BLOOD OXYGEN SATURATION MONITORING IN ESOPHAGOGASTRODUODENOSCOPY
Jun CHEN ; Jinhua ZHANG ; Zongshun CHEN
Chinese Journal of Digestive Endoscopy 1996;0(05):-
The purpose of this study was to reseach the relationship between the upper gastroin- testinal endoscopy and heart rare and blood oxygen saturation (SaO2 ) , 62 patients were examined by (esophagogastroduodenoscopy , EGD ) and monitored with a transcutaneous pulse oximeter simultane- ously. The mean age was 44. 5 years (range 21 - 68) , 30 males and 32 females. No sedative drugs and at- ropin were used. The mean pulse and SaO2 value before endoscopy were 94. 12/min and 97. 68%. During the ECD SaO2 was slightly decreased by a mean of 1 . 61% ( P 100/min accounted for 61 . 3%, it was more than preendoscopy (P
7.Sexual dysfunction in young male patients w ith stroke
Jinhua HUANG ; Jiahou XIN ; Wei CHEN
International Journal of Cerebrovascular Diseases 2015;23(12):917-923
As a key aspect of quality of life in patients w ith stroke, the clinical research of sexual function and sexual satisfaction is stil rare. The rehabilitation goals in patients w ith stroke usualy include recovering functional activities and improving quality of life, how ever, it is not yet know n about the recovery of sexual function. This article review s the epidemiology, etiology, risk factors, clinical manifestations, treatment and rehabilitation of sexual dysfunction in male patients w ith stroke.
9.Trans Jugular Intrahepatic Portosystemic Shunt in Treatment of Cirrhotic Patients with Esophageal and Gastric Variceal Bleeding.
Liqiang CHEN ; Peng YAO ; Jinhua XIONG
Journal of Medical Research 2006;0(03):-
Objective To discuss the efficiency and safety of transjugular intrahepatic portosystemic shunt(TIPSS) in treatment of cirrhotic patients with gastroesophageal variceal bleeding.Methods52 patients who had gastroesophageal variceal bleeding were treated with TIPSS,with 11 patients of them being active bleeding,23 patients being moderate to massive ascites.Results50 patients were treated successfully with the successful rate of 96.2%.The pressure of potal dropped from 3.87?0.50kPa to 2.45?0.40kPa(P
10.Matrine Compoand Injection Interrening the Liver Fibrosis Rat Induced by Tetrachloride.
Jinhua YU ; Chunhui SONG ; Guofeng CHEN
Journal of Medical Research 2006;0(03):-
Objective To examine the change of TGF-?1 in the bloods of rats which were induced by tetrachoride during the different times and to explain the mechanism of the change.MethodsThe experimental liver fibrosis induced by tetrachloride in rats was treated by matrine compound injection.Serum TGF-?1 and pathological changes in liver tissue were observed in control group,model group and therapy group during the time of the 4th,6th and 9th week.ResultsThere was an obvious change of TGF-?1 in the blood in different time and different groups.ConclusionMatrine compound injection has an antifibrogenetic action and TGF-?1 can reflect the change of liver fibrogenesis of different time as an index.