AIM: To investigate the effect of 17? estradiol (17?E 2)on atherosclerosis and hemorrheology in ovariectomized (OVX) rabbits. METHODS: Thirty four female rabbits were divided into 4 groups, group A: normal control; group B: sham+CHO; group C: OVX+CHO; group D: OVX+CHO+17? E 2. Cholesterol(CHO) was fed to rabbits for 12 weeks, before and after feeding CHO, the serum lipid (TC, TG, HDL-C, LDL-C, ApoA1, ApoB) and area of aortic atherosclerotic plaques were measured. Blood viscosity, plasma viscosity (?p), aggregation index of RBC (AIRC) and fibrinogen were also determined, respectively. RESULTS: ① The ratio of area of aortic atherosclerotic plaque to total area of aortic intima was 0.02?0.003 (in group A), 0.42?0.15 (group B), 0.67?0.23 (group C), and 0.12?0 11 (group D), respectively. In group D, the ratio of aortic atherosclerotic plaque was markedly decreased compared with group C ( P

Objective To explore the storage life and cost analysis of 0. 9% sodium chloride solution in 42℃ conveuse. Methods A total of 80 bottles of 0. 9% sodium chloride solution had been selected as research sampling, and the SAS 9. 2 were used to randomly divide them into control group (put sampling in clean laminar flow operation room at room temperature) and experimental group ( put in 42℃ conveuse) on average. Eight bottles of each group were took out for the number of colony examination after germiculture and the change of pH value ( at the beginning of 3 days, 1 week, 2 weeks, 3 weeks and 4 weeks experiment) . Basis on the previous experiment, we selected 12 operating room and randomly divided into A group and B group on average. A conveuse provided warm 0. 9% sodium chloride solution, which had three days storage life in A group, but B conveuse offered warm 0. 9% sodium chloride solution of 4 weeks storage life. Results The results of germiculture were negative in both group. The 5 time point of pH values were (6. 35 ± 0. 29), (6. 32 ± 0. 04), (6. 23 ± 0. 20), (6. 29 ± 0. 35), (6. 36 ± 0. 32) at the control group, while these of experimental group were (6.37 ±0.42), (6.31 ±0.11), (6.39 ±0.21), (6.42 ±0.45), (6.60 ±0.32)and at the same time point the pH value of two groups had no statistical significance (t=0. 110 8, 0. 241 7, 1. 561 0, 0. 645 0, 2. 111 0;P>0. 05). Compared with A group-consumed (2 761 ± 118) bottles, cost (11 042 ± 470) Yuan, B group consumed (1 466 ± 205) bottles and cost (5 862 ± 820) Yuan with statistical significance between two groups (t=13.41;P<0.01).Conclusions Thepreservationof0.9% sodiumchloridesolutionin42℃ conveusecan be maintained 4 weeks and reduced cost by the decreasing the number of usage, and the testing norm is accord with the acquirement of pharmacopeia.

Objective To explore the application value of comprehensive nursing path for patients with chronic pelvic inflammatory disease .Methods A total of 180 patients with chronic pelvic inflammation were randomly divided into observation group and control group on average .The control group received routine care for patients with chronic pelvic inflammatory disease , while the observation group underwent comprehensive comprehensive nursing path based on routine .The quality of life , effect of treatment and patients ’ satisfaction were compared .Results After intervention , the dimension assessment score of physical function , physical role , pain, health, vigor, social function, mental health and emotional function were (65.9 ±11.1),(67.8 ± 11.3),(68.1 ±10.0),(77.2 ±12.6),(70.8 ±11.0),(78.0 ±11.5),(77.6 ±11.3) and (80.4 ±10.7) in the observation group, which were better than those in the control group (t =6.983,9.042, 10.819, 19.037, 13.820, 25.174, 17.358, 28.974, respectively;P<0.01).The patients in the observation group had thirty six cured, twenty one dramatically effective, thirty effective and three invalid (Z=5.858,P<0.05). For assessment of satisfaction , there were seventy seven felt very satisfied , eleven satisfied and two unsatisfied (Z =6.678,P <0.05).Conclusions The comprehensive nursing path has a better therapeutic effect for patients with chronic pelvic inflammatory disease by improving the quality of life and treatment satisfaction .

To evaluate the loyalty and its influential factors for outpatients with high-end medical services in a comprehensive grade-A tertiary hospital.
 Methods: A total of 3 196 outpatients from July 2017 to June 2018, who visited the International Medical Department of a comprehensive grade A tertiary hospital, were investigated by a self-designed loyalty questionnaire. The Cronbach's alpha coefficient was 0.893. A third-party organization conducted the survey and 1 883 valid questionnaires were collected. Chi-square test and logistic stepwise regression model was used to analyze the influential factors for patients' loyalty.
 Results: The loyalty of outpatients with high-end medical services was 95.8%, and the satisfaction of all aspects of outpatient service was more than 94%. After adjusting for sex, age, the protective factors were diagnostic and therapeutic effect (OR=5.45, P<0.001), service level of nurses (OR=3.91, P=0.044), doctors' skills of communication and explanation (OR=2.95, P=0.046), degree of convenience (OR=3.04, P=0.038) and visits in recent three months (OR=2.11, P=0.008).
 Conclusion: The loyalty of outpatients with high-end medical services in a comprehensive grade A tertiary hospital is relatively high. Significant diagnostic and therapeutic effect, good service of nurses, good skills of communication and explanation, convenience and multiple visits are related to high loyalty.
Ambulatory Care ; Humans ; Outpatients ; Patient Satisfaction ; Surveys and Questionnaires ; Tertiary Care Centers