Objective To investigate current status of teachers' informational teaching ability in medical vocational college and provide reference for the improvement of teachers' informational teaching ability. Methods Convenience sampling method was adopted in survey. From September to December 2016,a total of 204 teachers from medical vocational college were investigated with the general information questionnaire and informational teaching ability questionnaire.Resluts The score of medical vocational college teachers' informational teaching ability was (3.50±0.66).Age and educational degree were the main factors influencing teachers' informational teaching ability (P<0.05).Conclusions Teachers' informational teaching ability in medical vocational was at medium level.In the future, we should pay attention to the two factors of age and education degree, and carry out the hierarchical and targeted training of teachers' informational teaching ability in medical vocational college.

Objective To explore the application of mobile app-based blended teaching inNursing Fundamentals.Methods Totally 101 nursing students from two classes of the School of Clinical Medicine and Nursing, Suzhou Vocational Health College were selected in September 2016. The two classes were divided into the treatment group (n=50) and the control group (n=51) respectively by drawing lots. The control group received conventional teaching, while the treatment group received mobile app-based blended teaching. The theoretical and practical performance were compared between the two groups at the end of course. Nursing students in the treatment group were evaluated with the self-designed Teaching Model Evaluation Questionnaire. Nursing students in the two groups were evaluated using the Autonomous Learning Competency Scale for Nursing Undergraduates before and after intervention.Results The theoretical and practical performance of the treatment group was (82.76±9.05) and (84.94±5.93) post intervention, both higher than that of the control group (t=-3.32, -7.99;P<0.05). The nursing students in the treatment group scored (94.82±7.31) post intervention, higher than that of the control group (t=-2.31,P<0.05). All nursing students in the treatment group believed the mobile app-based blended teaching was better than conventional teaching. Conclusions The mobile app-based blended teaching can improve the learning outcome of nursing students.

Objective:To summarize and analyze the clinical data of Chinese patients with colony-stimulating factor 1 receptor (CSF1R)-related leukoencephalopathy, and clarify the phenotypic and genetic characteristics of Chinese patients.Methods:Medical history of patients with CSF1R-related leukoencephalopathy diagnosed from April 1, 2018 to January 31, 2021 in the department of neurology of 22 hospitals in China was collected, and scores of Mini-Mental State Examination (MMSE), Montreal Cognitive Assessment Scale (MoCA), magnetic resonance severity scale were evaluated. Group comparison was performed between male and female patients.Results:A total of 62 patients were included, and the male-female ratio was 1∶1.95. The age of onset was (40.35±8.42) years. Cognitive impairment (82.3%, 51/62) and motor symptoms (77.4%,48/62) were the most common symptoms. The MMSE and MoCA scores were 18.79±7.16 and 13.96±7.23, respectively, and the scores of two scales in male patients (22.06±5.31 and 18.08±5.60) were significantly higher than those in females (15.53±7.41 , t=2.954, P=0.006; 10.15±6.26, t=3.328 , P=0.003). The most common radiographic feature was bilateral asymmetric white matter changes (100.0%), and the magnetic resonance imaging severity scale score was 27.42±11.40, while the white matter lesion score of females (22.94±8.39) was significantly higher than that of males (17.62±8.74 , t=-2.221, P<0.05). A total of 36 CSF1R gene mutations were found in this study, among which c.2381T>C/p.I794T was the hotspot mutation that carried by 17.9% (10/56) of the probands. Conclusions:The core phenotypic characteristics of CSF1R-related leukoencephalopathy in China are progressive motor and cognitive impairment, with bilateral asymmetrical white matter changes. In addition, there exist gender differences clinically, with severer cognitive impairment and imaging changes in female patients. Thirty-six CSF1R gene mutations were found in this study, and c.2381T>C/p. I794T was the hotspot mutation.