Objective:To explore the relationship between sleep quality and perceived stress and analyze the role of ego depletion and mindfulness in their relationship.Methods:Totally 326 police officers were selected and assessed with the Pittsburgh Sleep Quality Index(PSQI),Chinese Perceived Stress Scale(CPSS),Brief Ego Deple-tion Scale(BEDS),and Mindful Attention Awareness Scale(MAAS).Results:The average PSQI score was(9.1±3.0).There was a partial mediation effect between CPSS scores and PSQI scores,and the mediation effect ac-counted for 27.03％.The MAAS scores were regulated between CPSS scores and BEDS scores(β=-0.01,P＜0.01),CPSS scores and PSQI scores(β=-0.01,P＜0.001),and BEDS scores and PSQI scores(β=-0.02,P＜0.01).Conclusion:The sleep quality of the police officers is related to perceived stress,and ego depletion plays a mediating role between them,and mindfulness acts as a protective factor in the whole process.

The liquid chromatography tandem mass spectrometry was used to detect the urinary proteomics of 223 residents aged 40-69 years old who participated in the National Upper Gastrointestinal Cancer Early Detection Program in Linqu County, Shandong Province from November 22 to December 7, 2018, and analyze the alcohol consumption related proteomic profiles and individual urinary protein. There were significant differences in urinary protein profiles between alcohol consumption group and non-alcohol consumption group. The expression of 26 urinary proteins was up-regulated and 20 urinary proteins were down-regulated in alcohol consumption group ( P<0.05). The differentially expressed proteins had enzyme inhibitor activity and phospholipid binding function, and mainly enriched in pathways involving proximal tubule bicarbonate regeneration, complement and coagulation cascade, and cholesterol metabolism. The protein expressions of complement factor I (CFI), angiotensin converting enzyme 2 (ACE2) and protein C inhibitor (SERPINA5) were positively correlated with daily alcohol consumption.

The liquid chromatography tandem mass spectrometry was used to detect the urinary proteomics of 223 residents aged 40-69 years old who participated in the National Upper Gastrointestinal Cancer Early Detection Program in Linqu County, Shandong Province from November 22 to December 7, 2018, and analyze the alcohol consumption related proteomic profiles and individual urinary protein. There were significant differences in urinary protein profiles between alcohol consumption group and non-alcohol consumption group. The expression of 26 urinary proteins was up-regulated and 20 urinary proteins were down-regulated in alcohol consumption group ( P<0.05). The differentially expressed proteins had enzyme inhibitor activity and phospholipid binding function, and mainly enriched in pathways involving proximal tubule bicarbonate regeneration, complement and coagulation cascade, and cholesterol metabolism. The protein expressions of complement factor I (CFI), angiotensin converting enzyme 2 (ACE2) and protein C inhibitor (SERPINA5) were positively correlated with daily alcohol consumption.