1.Meta anlaysis on effects of resistant starch on metabolism of type 2 diabetes mellitus
Ludan QIN ; Jingya DING ; Yong XU
Chongqing Medicine 2017;46(36):5141-5144,5148
Objective To discuss the effects of resistant starch (RS ) on metabolism of type 2 diabetes mellitus (T2DM ) . Methods The databases of Pubmed ,Ovid ,Embase and Cochrane Library were retrieved for search the randomized controlled trials (RCTs) on RS intervention on T2DM .The retrieval time was until June 21 ,2016 .The literature quality was assessed by using the bias risk evaluation tool recommended by Cochrane collaboration net .The related data were integrated and analyzed by using the Stata 12 .0 software .Results A total of 909 articles were retrieved out ,in which 6 articles met the included criteria and 308 cases were included as the research subjects .All the studies demonstrated that fasting blood glucose(FBG) in the patients with T2DM was decreased significantly after RS intervention .Four studies detected postprandial blood glucose and considered that postprandial glucose was decreased significantly after RS intervention (P=0 .023 ,P=0 .010 ,P<0 .05 ,P=0 .045) .Three studies .reported the related data of fasting total cholesterol(TC) and triglyceride(TG) ,but the study results were greatly different from each other .3 stidies indicated that compared with control group ,the HDL-C level of the RS group was significantly increased (P<0 .05) ,while the level of LDL-C had no obvious difference .In Bodinham′s .study ,HDL-C and LDL-C had no obvious difference between the two groups .The study by Gargari′s and Bodinham′s .thought the level of TNF-αin the RS group was significantly decreased (P<0 .05 , P=0 .013) ,however ,the former thought that the level of IL-6 in the RS group was also decreased ,while the latter thought that compared with the control group ,the IL-6 level had no significant difference .Conclusion RS can increase insulin sensitivity inT2DM patients ,and improves glucolipid metabolic disorder .
2.Factors Influencing Inpatient Costs for Patients Undergoing Surgery for Intrauterine Lesions under DRG Payment
Yutong WANG ; Weiguo ZHU ; Xueqin SUN ; Jiali TONG ; Jingya ZHOU ; Qing ZHAO ; Bocheng LI ; Wei ZHANG ; Xiaokun LIU ; Rui DONG ; Chen XIE ; Ding HAN
Medical Journal of Peking Union Medical College Hospital 2024;15(5):1069-1076
To analyze the factors affecting the cost of hospitalization for patients and provide insights using the intrauterine lesion surgery group (DRG code NE19) as an example. This study was a retrospective cross-sectional study, with data from the first page of medical records of patients enrolled under NE19 at a comprehensive tertiary hospital in Beijing from March 15, 2022 to November 30, 2023. Influence factor selection and multifactorial linear regression analysis were conducted with hospitalization cost as the dependent variable, and patient's basic information, treatment information and key concern factors as independent variables. The profit and loss of medical records containing key factors and differences in indicators of hospitalization cost structure were analyzed in the context of clinical practice. A total of 2213 valid medical records (all female patients) were included, with patients predominantly young and middle-aged women under 45 years of age (72.12%), and with 931 day surgery medical records (42.07%). The diagnosis records included 334(15.09%) multiple uterine leiomyomas, and 246(11.12%) pelvic adhesions. A total of 150(6.78%) medical records involved ovary- and tubal-related surgeries or manipulations, with 160(7.23%) main operations being laparoscopic hysterectomy of diseased uterine lesions and 38(1.72%) mechanical rotational excision of abnormal uterine tissue using transhysteroscopy. Linear regression analysis showed that whether or not ovarian and tubal surgical operations were involved ( The NE19 group of hospitals in the study had a high loss rate, and factors such as the severity of the patient's condition and the use of new technologies affected hospitalization costs, suggesting that there is room for further optimization of the existing grouping scheme. Tiered payment standards can be set up for different tiers of healthcare institutions, and a sound and optimized exclusion mechanism can be used to promote the development of new technologies. The internal management of hospitals should encourage the development of daytime surgery to improve the efficiency of medical services.