The article summarized and analyzed the research fund for doctoral programs at Peking Union Medical College during the 10th and 11th Five-Year period.A further exploration into the fund's management pattern was made and suggestions on how to improve the management were also proposed.

From 2004 to 2013,Peking Union Medical College had implemented technology innovation plans to build 12 innovation teams funded by Ministry of Education.This paper made statistical analysis of the results and achievements of the team building initiatives and put forward new ideas and measures for future development.

The Union Youth Science & Research Fund was set up by the Peking Union Medical College (PUMC) using the Fundamental Research Funds for the central universities.Education Ministry's National College Special Fund for Basic Science& and Research drafted and implemented its own management rules.The rules standardize the fund's various aspects including its system construction,project classification,implementation terms,outlay management,and project management.In consequence,the rules promoted the young teachers' research on funded-subjects and improved the management level on scientific research projects.

Objective To analyze the clinical presentation and the effects on both mothers and fetuses with HELLP syndrome induced hyregtensive disorder complicating pregrancy and to investigate the effective methods for diagnosis and treatment. Methods 15 cases of HELLP syndroms were retrospectively analyzed on material and perinatal outcomes. Results In 15case of women with HELLP syndrome, all of them presented antepartum HELLP. Mean gestational age at delivery was 34 weeks. Severe maternal complications included placental abruption,DIC ,postpartum hemorrhage,fetal distress, et al. All of them underwent cesaresn section and required transfusions with blood or blood products. 1 case of perinatal death was related to placental abruption. Conclusion HELLP syndrome is a severe obstetric complication. Better prognosis may be achiveved by early diagnosis, synthetic therapy and optimal termination of pregnancy.

Fuwai Hospital of Chinese Academy of Medical Sciences constructed three research plat-forms by integration of resources in 2004 which included central laboratory, pathophysioiogy center and ani-mal center. It mainly aimed to provide the use of equipment, technical training, guidance and experimental animals, etc. For hospital researchers and graduate students in this paper, we reviewed the three research platforms and analyzed the positive effect of research platforms on personnel training and promoting the re-search and development of the hospital.

Introduced the the national experimental cell resource sharing platform construction process and its function.Summerize the content,experience and outcome of the cell resource physical platform and information services since it launched,analysed the problems existing in the current platform running,and proposed solutions to address these issues,pointed out the next step in the development.

OBJECTIVE:To analyze the resistance of the main pathogens in our hospital to antimicrobials for clinical reference of rational use of antimicrobial agents. METHODS:The antibiotic resistance of the clinical pathogens in our hospital in 2008 was retrospectively analyzed. RESULTS:Of the total 938 clinical pathogenic bacteria isolated in our hospital,the most common pathogens(leading the first 10 places)were E. coli,staphylococcus aureus,enterobacter spp,staphylococcus epidermidis,pseudomonas aeruginosa,Klebsiella,acinetobacter,enterococcus,hemolytic streptococcus and bacillus proteus. CONCLUSION:Clinicians should use antimicrobial agents rationally to reduce the antibiotic resistance.

Objective To investigate the effect and mechanism of boron neutron capture therapy(BNCT) in C6 glioma cell line.Methods C6 cells in exponential phase were divided into 6 groups: untreated control,(~(60)Co?)(4 Gy),~(60)Co? 8 Gy,nuclear reactor exposure without boronophenylalanine(BPA) 3 Gy,BNCT(4 Gy) and BNCT 8 Gy.Cellular morphological change was observed by an inverted microscope,light microscope,fluorescence microscope and electronic microscope.Flow cytometry was used to determine the percentage of apoptosis,necrosis and normal cells 48h after irradiation.Colony forming assay was used to calculate cell surviving fraction.Results Typical morphological changes of apoptosis were observed early after irradiation in BNCT group,with a significant increase in apoptotic rates was observed 48 h after irradiation with 63.2% and 88.3% for BNCT(4 Gy) and 8 Gy group,respectively(P

Objective To analyze the distribution features of systemic vascular resistance(SVR)disorder in healthy subjects at Guangxi province.Methods SVR and systolic blood pressure(SBP),diastolic blood pressure(DBP),mean arterial pressure(MAP),pulse pressure(PP),cardiac output(CO),cardiac index(CI),stroke volume(SV),stroke index(SI),left ventricular ejection time(LVET),left cardiac work(LCW) and cardiovascular function were measured with Bioz.com Cardio Dynamics.Results The incidence of SVR disorder in youngster and elder was higher than other subjects.The prevalence of SVR disorders was more among females than among males(P

Aim To study the antitumor and immunological regulation effects of ardipusilloside-Ⅰ(ADS-Ⅰ) on tumor-bearing mice of S180, H22, EAC and L1210. Methods The tumor-bearing mouse model was made through injecting cancer cells in the right limb oxter(or in abdominal cavity), and the mice were administrated orally with ADS-Ⅰfor 8 days. Then we detached the tumor and counted the inhibition rate of tumor growth. Incorporation of ()~3H-TdR was used to assess the proliferation of T spleen lymphocyte cells; phagocytosis of abdominal cavity macrophage was measured with the method of chicken red blood cells. Results ADS-Ⅰ was proved to be effective on the tumor-bearing mice of S180, H22 and EAC, and the maximal inhibition rate of the dose of 100 mg?kg~(-1) was 38.7%, 48.6% and 50.0%, respectively;ADS-Ⅰ promoted the proliferation of T spleen lymphocyte cells,and strengthened the phagocytosis of macrophage in the tumor-bearing mice significantly. Conclusion ADS-Ⅰ can inhibit the growth of transplanted tumor,and improve the immunological function of tumor-bearing mice.