Objective To study the curative effect of posterior microendoscopy discectomy (MED)in the treatment of lumbar disc herniation(LDH). Methods 57 patients with LDH were treated by posterior MED to evalu-ate the curative effect. Results 57 patients were followed up for 3～12 months( average,6.5 months) ,the excellent and good rate was 91.2% (52/57). Conclusion Posterior MED has the advantages of less trauma,prompt recovery and less complications.

Objective To research the clinical application in operation of small incision to treat the protrusion of lumbar intervertebral discs.Methods 36 cases with the protrusion of lumbar intervertebral discs in diferent inter- vertebral space were treated with operation of small incision.Results All cases were followed up for four months to three years.According to Maenab criteria,the outcomes were excellent in 23 cases,good in 9 cases,fair in 3 cases, and excellent and good rate were 91.7 %.Conclusion The method of small incision technique was a very promising way to treat the protrusion of lumbar intervertebral discs with less trauma,quicker recovery,better results and mini- mal damage to spinal structure.

Abstract The metabolic level of children and adolescents is of great significance in the healthy growth and development of children and adolescents. Irisin, as a myokine, was first discovered and named in 2012. Early studies showed that irisin can participate in body metabolism and inhibit the occurrence of obesity. Later studies found that irisin can improve the symptoms of type 2 diabetes mellitus, metabolic syndrome, osteoporosis and other diseases. At the same time, irisin can promote glucose, lipid metabolism and bone metabolism in children and adolescents, and its mechanism is still controversial. In this review, research update regarding the effect of irisin/FNDC5 on metabolism (lipid metabolism, glucose metabolism, bone metabolism) in children and adolescents were summarized in order to provide theoretical reference for researchers in the field of the metabolism of children and adolescents.

Objective:To establish a standardized nursing management model for hypoglycemia in diabetic inpatients and observe its application effects.Methods:Totally 9 251 diabetic patients hospitalized in People's Hospital of Zhengzhou between January and December 2017 were selected into the control group, while another 9 636 diabetic patients hospitalized in People's Hospital of Zhengzhou between January and December 2018 were selected into the observation group by cluster sampling. Patients in the control group received routine care and glycemic management. In 2018, in conjunction with the glycemic monitoring system, we established a diabetes education management team and developed a standardized nursing management process for hypoglycemia, which was promoted throughout the hospital to improve the level of hypoglycemic control among nurses throughout the hospital. Patients in the observation group received care and glycemic control using the standardized nursing management model for hypoglycemia and glycemic control. The incidence of hypoglycemia, glycemic fluctuations, and nurses' knowledge of hypoglycemia before and after implementation were compared between the two groups.Results:The incidence of hypoglycemia in the observation group was lower than that in the control group [7.51% (724/9 636) vs. 18.30% (1 693/9 251) ], and the difference was statistically significant (χ 2=492.7, P<0.001) . The observation group's average blood glucose value (GluAve) , daily mean amplitude of glycemic excursions (MAGE) , glycemic instability index (GLI) , and glycemic coefficient of variation (GluCV) were all lower than the control group, and the differences were statistically significant ( t=-18.121, -53.788, -34.362, -61.794; P<0.01) . After the implementation of the standardized management model for hypoglycemia in 2018, the total score dimensional scores of the nurses' knowledge about hypoglycemia were higher than those before the implementation of the standardized nursing process for hypoglycemia in 2017, and the differences were all statistically ( t=15.439, 66.542, 73.320, 14.565, 36.101, 34.664; P<0.01) . Conclusions:The standardized nursing management model for hypoglycemia can reduce the incidence of hypoglycemia as well as fluctuations of the patients, improve the level of nurses' knowledge of hypoglycemia, and make the patients' glycemic control safer.

Objective:To explore the effect of continuous blood glucose monitoring combined with dietary goal intervention in patients with newly diagnosed type 2 diabetes.Methods:From June to December 2021, 274 newly diagnosed type 2 diabetes patients were selected by convenience sampling from the Department of Endocrinology of People's Hospital of Zhengzhou. The patients were randomly divided into a control group and an observation group, with 137 cases each. The control group adopted routine diabetes nursing management, and the observation group implemented continuous blood glucose monitoring combined with dietary goal intervention on the basis of the control group, with a management period of one month. We compared the blood glucose fluctuation coefficient, blood glucose compliance rate, and incidence of hypoglycemia between the two groups.Results:The fasting blood glucose fluctuation coefficient and the 2-hour postprandial blood glucose fluctuation coefficient in the observation group were lower than those in the control group, and the differences were statistically significant ( P<0.05). The blood glucose compliance rates of the control group and the observation group were 49.64% (68/137) and 75.18% (103/137), respectively, with statistically significant difference ( P<0.05). The incidences of hypoglycemia in the control group and the observation group were 28.47% (39/137) and 7.30% (10/137), respectively, with statistically significant difference ( P<0.05) . Conclusions:Continuous blood glucose monitoring combined with dietary goal intervention can effectively improve the blood glucose compliance rate in patients with newly diagnosed type 2 diabetes, reduce the incidence of hypoglycemia, and have certain advantages in stable control of blood glucose.

Cardiovascular disease (CVD) is the most common and fatal non communicable disease in the world. Hypertension accounts for a large proportion of global non communicable diseases. Irisin was first discovered and named in 2012. As a muscle myokine, irisin has the function of regulating glucose and lipid metabolism. Exercise can promote irisin' participation in energy metabolism in the body. At the same time, it has been found that irisin can intervene in the development of hypertension and have a positive effect on the improvement of hypertension. Therefore, this paper reviews research on the relationship between irisin and hypertension, summarizes the mechanism of irisin’ action on vascular function in hypertension, and analyzes the effect of irisin on blood pressure under exercise intervention.

Cardiovascular disease (CVD) is the most common and fatal non communicable disease in the world. Hypertension accounts for a large proportion of global non communicable diseases. Irisin was first discovered and named in 2012. As a muscle myokine, irisin has the function of regulating glucose and lipid metabolism. Exercise can promote irisin' participation in energy metabolism in the body. At the same time, it has been found that irisin can intervene in the development of hypertension and have a positive effect on the improvement of hypertension. Therefore, this paper reviews research on the relationship between irisin and hypertension, summarizes the mechanism of irisin’ action on vascular function in hypertension, and analyzes the effect of irisin on blood pressure under exercise intervention.