1.Investigation and analysis in the coping style and influencing factors of the recipients after relative kidney transplantation
Xiaoyun MENG ; Hong TAN ; Jingrui WANG
Chinese Journal of Practical Nursing 2009;25(11):81-83
Objective To investigate the coping style and influencing factors of the recipients after relative kidney transplantation. Methods Medical coping modes questionnaire (MCMQ) and observa-tion interview were performed in the sampling survey, 56 case of recipients after relative kidney transplanta-tion according to the adopted standard were analyzed. Results The confronting score of all the cases were close to that of normal model, but the avoiding score and yielding score significantly increased. The prospective health conditions of the relative donors, function and survival time of the graft kidney, rejection reaction and other complication after transplantation were the main factors affecting the coping style of the recipients. Conclusions Based on the accurate evaluation of the coping style, nursing intervention should be aimed at the recipients following relative riving donor kidney transplantation, in order to help the recipients create a correct coping style and improve the survival rate of patient/kidney.
2.Progress in role of mesenchymal stem cell-derived extracellular vesicles in regulating myocardial ischemia-reperfusion injury
Jingrui TAN ; Yongxin JIANG ; Shiyuan WANG
Chinese Journal of Pathophysiology 2024;40(1):187-192
Currently,revascularization is an effective rescue strategy for patients with acute myocardial infarc-tion.However,myocardial ischemia/reperfusion(I/R)injury induced by revascularization has become a significant risk factor affecting the long-term prognosis of patients with ischemic cardiomyopathy after revascularization,without precise treatment.Extracellular vehicles derived from mesenchymal stem cells are characterized by easy access,editability,and easy absorption of cells,and their application in treating myocardial I/R injury is considered valuable to study.This review focuses on the advances in research on mesenchymal stem cell-derived extracellular vehicles and their function of regulating myocardial I/R injury after natural drug intervention,hopefully offering ideas for the research of prevention and treatment of myocardial I/R injury.
3.Development and reliability and validity of a Discharge Preparation Scale for Diabetic Foot Patients
Lei HOU ; Ping ZHANG ; Jingrui LI ; Xiaoyan ZOU ; Yi HU ; Ying TAN
Chinese Journal of Nursing 2024;59(19):2333-2339
Objective Based on the theory of Information-Knowledge-Attitude-Practice(IKAP),the reliability and validity of the discharge preparation scale for patients with diabetic foot(DF)was developed and tested,which is in accordance with the national conditions and disease characteristics of our country.Methods Based on the IKAP theoretical framework,articles were identified through literature analysis,qualitative interviews and Delphi method.After pre-investigation,a total of 483 patients with DF were selected from 3 general hospitals in Jiangxi province from June 2023 to February 2024.The items were screened by item analysis,and the reliability and validity were tested.Results The discharge preparation scale for patients with DF included 4 dimensions and 29 items.The Cronbach's α coefficient was 0.934;the scores of each dimension Cronbach's α coefficient ranged from 0.889 to 0.947;the overall split-half reliability was 0.966,and the split-half reliability of each dimension ranged from 0.901 to 0.952.A total of 4 common factors were extracted by exploratory factor analysis,and the cumulative contribution rate of variance was 68.074%.The x2/df value of confirmatory factor analysis was 1.906.The fitting fit of the model is suitable.The content validity was 0.973 at scale level and 0.875~1.000 at item level.Conclusion The reliability and validity of the discharge preparation scale for patients with DF are good,and it can be used as a tool to evaluate the discharge preparation for patients with DF.