Objective To evaluate the clinical effect of lumbar intervertebral disc herniation (LIDH) by CT-guided precise injection around nerve root and in epidural cavity. Methods One hundred and eight patients of LIDH were treated by CT-guided precise injection around nerve root and in epidural cavity, and followed-up after 1, 3 and 6 months. Visual analogue score (VAS) for pain was used to evaluate the efficacy before and after treatment. Results In 108 cases, there were 83 patients (76.9%) with good result whose improvement of VAS was greater than or equal 50% after treatment 1, 3 and 6 months. There were 19 patients (17.6%) with fair result whose improvement of VAS was less than 50% after treatment 1, 3 and 6 months. There were 6 patients (5.6%) with invalid result whose improvement of VAS was unobvious after treatment 1, 3 and 6 months. Conclusion CT-guided therapy of LIDH by precise injection around nerve root and in epidural cavity is safe, accurate, effective, minimally aggressive technique and worth being practiced clinically.

Objective:To study the effect of B7-1 costimulatory molecule in inducing tumor immunity.Methods:The lymphocytes were examined in vitro,for both proliferation induces(PI) and specific cytotoxic activity,H22 mice were challenged subcutaneously either by the mock following which the latency,survival time and tumor mass growth were noted.Results:The H22-B7-1 cells more effectively induced the proliferation of effecter lymphocytes and the generation of specific lytic activity against H22 cells.The H22-B7-1 cells demonstrated slower rate(P

Objective To evaluate the category of the variations on bilateral renal artery and clinical significance with 64-slice spiral CT angiography. Methods CT angiography of 250 patients were retrospectively analyzed. The variations on bilateral renal artery were observed and classified. Results According to the number of the main renal artery, the anatomy of renal artery was classified and typed in details. The incidence of the variations on renal artery in the patients and kidneys was 39.20% (98/250) and 22.80% (114/500), respectively. The incidence of early branch of the main renal artery and accessory renal artery was 9.60% (48/500) and 11.80% (59/500), respectively. No statistical difference of variation incidence was found between male and female, nor between left and right kidneys. The incidence of unilateral and bilateral variations on renal artery was 32.80% (82/250) and 6.40% (16/250), respectively, and the combinations of the latter were multiform. Conclusion Anatomical variations on renal artery can be showed clearly with 64-slice spiral CT angiography. Variations on bilateral renal artery are important to select the donor in case of renal transplantation.

Objective: To determine luteolin 7 O ? D glucoside in Chrysanthemum morirolium Ramat. Methods: The content of luteolin 7 O ? D glucoside was determined by HPLC on Symmetry Shield TM RP S column with MeoH H 2O(49∶51) as a mobile phase and detection wavelength at 348nm. Results: The liuear relationship of this method was well and the average recovery of the added sample is 99.74%. Conclusion: The analytical time is short, separating degree is good and results are accurate when luteolin 7 O ? D glucoside is determined by this method.

Objective To evaluate the value of multislice spiral CT in preoperative staging of bladder carcinoma.Methods Eighty-two patients(78 males and 4 females)with pathologically proved bladder carcinoma and the radiology materials were retrospectively analyzed.All the diagnosis results were compared with the results of surgical pathology.Results The location accuracy and qualitation accuracy in the diagnosis of bladder carcinoma with spiral CT WaS 78.0%(64/82)and 93.9%(77/82)respectively.Compared with the results of surgical pathology,the accuracy of judgement in bladder surrounding involvement,lymph node metastasis and surrounding organ involvement with CT was 90.2%(74/82),96.3%(79/82)and 89.0%(73/82),respectively.The CT staging of bladder carcinoma was positively correlated to that of surgical pathology.Conclusions Spiral CT has high value in the diagnosis of bladder carcinoma.It could be adopted as a conventional and main examination of bladder carcinoma before operation.

Objective: To examine the correlation between visuospatial construction ability and occupational aluminum exposure among aluminum workers, so as to provide the evidence for early protection of occupational injury among aluminum workers. Methods: A total of 442 workers in an aluminum factory in Shanxi Province were selected using a cluster sampling method, and participants' demographic features and occupational history were collected. The blood aluminum concentration was measured using inductively coupled plasma mass spectrometry (ICP-MS), and the visuospatial construction ability was evaluated with the Cube Copying Test (CCT) of the Chinese version of the Montreal Cognitive Assessment (MoCA). The correlation between the visuospatial construction ability and blood aluminum concentration was examined using a multivariable logistic regression model. Results: A total of 442 aluminum workers were enrolled, and all participants were male, with a mean age of (43.40±7.31) years, labor service duration of (23.64±8.35) years and a mean blood aluminum concentration of 33.87 µg/L. Of all participants, there were 206 workers with impaired visuospatial construction ability (46.61%), including 127 workers with blood aluminum concentrations of >33.87 µg/L (61.65%); 190 workers with educational duration of 6 to 9 years (92.23%), 118 electrolytic aluminum workers (57.28%), 114 workers with work shifts (55.34%), and 123 workers with a very good sleep quality (59.71%). Multivariable logistic regression analysis revealed that blood aluminum concentrations of >33.87 µg/L (OR=2.490, 95%CI: 1.531-4.052), educational duration of 6 years or more (OR: 0.075-0.246, 95%CI: 0.015-0.622), work type as a non-electrolytic aluminum worker (OR=0.838, 95%CI: 0.425-0.987), work shift (OR=1.179, 95%CI: 1.078-1.435) and a very good sleep quality (OR=0.104, 95%CI: 0.012-0.896) significantly correlated with impaired visuospatial construction ability among aluminum worker. Conclusion Impaired visuospatial construction ability correlates with occupational aluminum exposure among aluminum workers.

Objective To establish a distraction osteogenesis SD rat model for exploring the effect of total flavonoids from Rhizoma Drynariae on the quality of rat bone formation in the process of distraction osteogenesis from the perspective of tomography.Methods Twenty-four rats were randomly divided into experimental group and control group after successful modeling,and were respectively given intragastric administration with total flavonoids from Rhizoma Drynariae(in dose of 77.125 mg/kg) and saline for 8 weeks.Seven days after operation,the tibias of all the rats were given distraction at the speed of 0.2 mm for 20 days.Eight weeks after the operation,X-ray examination for all the rats was performed,and then the rats were killed for obtaining the tibia samples for Micro-CT scanning.The differences of X-ray Lane-Sandhu scores,the bone mineral density and bone mineral content were compared between the two groups.Results The X-ray Lane-Sandhu scores,the bone mineral density and bone mineral contents showed by Micro-CT scanning in the experimental group were higher than those in the control group,and the differences were statistically significant (P ＜ 0.05).Conclusion The total flavonoids from Rhizoma Drynariae can improve the quality of bone formation in the process of distraction osteogenesis in rats.

Objective: To explore the incidence and influencing factors of child emotional neglect, and to provide evidence for the relevant departments to prevent child emotional neglect. Methods: Stratified random cluster sampling method was used to select 1 354 parents from a county of Henan Province. Anonymous questionnaire survey was conducted among them to investigate child emotional neglect, logistic regression analysis was used to analyze the influencing factors of emotional neglect. Results: The total incidence of child emotional neglect was 15.7%, and the rate of boys and girls was 14.7% and 16.8%, respectively, that of fathers and mothers was 18.3% and 15.1%, respectively. There were no statistically significant differences in rates between fathers and mothers’ emotional neglect behaviors, neither between boys and girls (χ2=1.18，3.14, P>0.05).90.2% parents could often/always console children when they were hurt or feared. Multivariate logistic regression analysis showed that risk factors of high emotional neglect incidence included living in rural areas, poorer family economic status, parents with lower social support and childhood neglect experience, biological parents are not married(OR=2.71, 2.56, 2.64, 2.66, 4.11, 1.76, P<0.05). Conclusion Parents’ emotional neglect of kindergarten children existed in the research area, attention should be paid to the emotional neglect of parents from rural areas, and parental education activities should be carried out to enhance parents’ parenting skills.

Objective: To investigate the ethical decision-making process of breaking confidentiality when counselors dealing with self-inflicted injury and suicide issues in college situation. Methods: A semi-structural interview was addressed to 10 counselors from 7 college counseling centers in Beijing, among whom with (10 ± 8) years of experience on average in this field. Content analysis method was used to transcription of the interviewing data. Results: Totally 8 counselors had received ethical training more or less, and attached great importance to ethical codes. There were still some conflicts between school regulations and confidentiality rules in 7 university counseling centers. Different counselors varied greatly in decision-making on breaking confidentiality when facing college students' self-inflicted injury and suicide. Faced with conflicts between college demands and confidentiality principles, counselors could take the professional standpoint and consider more of the interests of students. Conclusion: The decision-making process on self-inflicted injury and suicide confidentiality breakthrough needs to be standardized. College's attention and support to the counseling work should be strengthen and enhance ethical awareness.

At present , methamphetamine has become a major hidden danger in global public health safety. In order to judge methamphetamine addicts and methamphetamine abstainers more scientifically and reliably, this study analyzed the endogenous metabolites in plasma, serum and urine of methamphetamine addicts, methamphetamine abstainers and healthy volunteers by highly sensitive high-throughput liquid chromatography quadrupole time-of-flight mass spectrometry (LC-QTOF-MS) analytical instrument. The obtained metabolomic data were processed by univariate analysis (t-test) and multivariate analysis (PLS-DA and OPLS-DA) and eligible potential biomarkers were then screened.The identified biomarkers set enrichment analysis to find the connection between metabolites and metabolic pathways.Multivariate statistical results showed that methamphetamine acute group, recovery group and healthy group were clearly separated.3, 18 and 6 regulated metabolites were identified in serum, plasma and urine, respectively, suggesting that lipid metabolism was abnormal in methamphetamine acute group, and that fatty acid metabolism, sulfate/sulfite metabolism and sex hormone metabolism were abnormal in methamphetamine recovery group.The selected potential biomarkers in this study provide the possibility for scientific judgment of the clinical stage of methamphetamine detoxification.