1.Quantitative variation of total alkaloids contents in Dendrobium officinale.
Yan ZHU ; Ailian ZHANG ; Bowei HE ; Xinfeng ZHANG ; Qiaoxian YU ; Jingping SI
China Journal of Chinese Materia Medica 2010;35(18):2388-2391
OBJECTIVETo investigate the total alkaloid content and find out the variation of total alkaloids content in Dendrobium officinale with different germplasms and harvesting ages with the aim of providing scientific basis for the authenticity identification and the breeding of D. officinale.
METHODForty one samples with 1-3 ages were collected from cultivated fields of Zhejiang and Yunnan provinces and 11 samples were collected from markets. The total alkaloid contents of samples were determined using acid-dye colorimetry method.
RESULTThe determined total alkaloid contents in D. officinale ranged 0.0190%-0.0430%. The averages of total alkaloid contents were 0.0253%, 0.0270% and 0.0326% in 1-year-old, 2-year-old and 3-year-old samples of Zhejiang province, respectively. The average of total alkaloid content was 0.034 3% in 1-year-old samples of Yunnan province.
CONCLUSIONThe total alkaloid content of D. officinale with different germplasms and physiological ages existed significant discrepancy, and it increased with the growth of ages. The total alkaloid content of cultivated D. officinale in Yunnan province was higher than that in samples from Zhejiang province. But the authentic D. officinale had certain range of total alkaloid content. Samples whose total alkaloids content divagates from this range must be counterfeit; Samples whose total alkaloid content is in this range still need to combines with other active chemical groups like polysaccharides content to identify the authenticity and quality of medicinal materials.
Alkaloids ; analysis ; metabolism ; China ; Dendrobium ; chemistry ; metabolism ; Plant Extracts ; analysis ; metabolism
2.Expert advice on practical use of amisulpride in treatment of schizophrenia
Ying LIANG ; Dengtang LIU ; Tianmei SI ; Yi LI ; Congpei ZHANG ; Tao LI ; Xiufeng XU ; Chengge GAO ; Zhimin WANG ; Li KUANG ; Qingrong TAN ; Zhiyu CHEN ; Shenxun SHI ; Tiebang LIU ; Fude YANG ; Gaohua WANG ; Jingping ZHAO ; Kaida JIANG ; Xin YU
Chinese Mental Health Journal 2017;31(6):425-431
Amisulpride,a kind of the second generation antipsychotics,was marketed in China in 2010.A series of clinical research and experience before and after listed,especially the data based on Chinese population,provided evidence for the generalization and application of amisulpride.In order to optimize the clinical application of amisulpride,and improve the prognosis of patients,Expert Advice on the Practical Use of Amisulpride in the Treatment of Schizophrenia is presented here.This advice is based on the recent evidence and clinical experience,for guiding the clinical medication of amisulpride.