Objective To review the application scope of risk communication based on eHealth technology in the primary prevention of cardiovascular diseases,so as to provide references for future research and application.Methods A systematic search was conducted in PubMed,Cochrane Library,Embase,Web of Science,CINAHL,PsycINFO,CNKI,Wanfang database,and SinoMed.The search time limit was from the establishment of databases to March 1,2024.The included literature was summarized and analyzed.Results A total of 24 articles were included.The forms of eHealth technology applied in risk communication for primary prevention of cardiovascular include online websites,computerized decision support systems,electronic health records,mobile applications,email,telephone,and text messages.The functions include risk assessment,risk notification,personalized advice,risk tracking and reminders.The outcome indicators include risk perception,physiological indicators,lifestyle and behavior,psychological indicators,feasibility evaluation,decision correlation,doctor-patient communication,intention,risk score,and physician drug prescription.Conclusion The use of eHealth technology in risk communication of cardiovascular diseases has potential value in improving patients'risk perception and promoting healthy behaviors.It is necessary to continuously improve the functions of eHealth technology and enhance its precision and intelligence,so as to better meet the needs of medical staff and patients and promote the efficient implementation of primary prevention of cardiovascular diseases.

Objective:To evaluate the effect of sex factors on rewarming in patients with mild hypothermia undergoing lithotripsy for urolithiasis.Methods:In this prospective study, 100 American Society of Anesthesiologists Physical Status classification Ⅰ or Ⅱ patients, aged 18-60 yr, with a body mass index of 18-30 kg/m 2, scheduled for elective lithotripsy for urolithiasis, were divided into 2 groups ( n=50 each) based on sex: male group (group M) and female group (group F). The rewarming measures were as follows: the room was preheated, maintaining a constant temperature of 22-24 ℃, all the patients were covered with medical heating blanket under their bodies, and the inflatable heating apparatus was placed on the surface quilt, and the air supply was placed near the lower limbs of the patients. The parameters were set as follows: temperature 40 ℃, strong wind. If the patients complained of heat, the temperature parameter settings were changed, and the quilt was removed when necessary. If the patients complained of cold, blood transfusion and infusion heating instrument were added, medical heating blanket was turned on, or an anther quilt was used. Body temperature and the number of patients with successful rewarming were recorded on admission to post-anesthesia care unit (T 0) and at 10, 30, 45 and 60 min after rewarming (T 1-4), and at 1, 3 and 5 h after returning to the ward (T 5-7). The comfort scores were assessed while measuring body temperature at T 0 and T 4, and the occurrence of shivering, hypertension, hypotension and arrhythmias was observed. Results:Compared with group F, the body temperature was significantly increased at T 3 and T 4, the success rate of rewarming and incidence of shivering were increased at T 3 ( P<0.05), and no significant change was found in the incidence of hypertension, hypotension and arrhythmias in group M ( P<0.05). Conclusions:Sex factors affect rewarming outcomes in patients with mild hypothermia undergoing lithotripsy for urolithiasis. Females exhibit a slower rewarming rate and less shivering than males.

Objective To explore the correlation between serum insulin-like growth factor1(IGF-1),insulin-like growth factor binding protein3(IGFBP-3),bone-specific alkaline phosphatase(BAP)and abundance of intestinal flora in children with idiopathic short stature(ISS).Methods A total of 86 children with ISS who were treated with short-acting recombinant growth hormone for the first time in Department of Endocrinology of Baoding Hospital,Beijing Children's Hospital,Capital Medical University,were enrolled from July 2021 to June 2023.Before treatment and at 6 months after treatment,physical indexes(height,weight)and bone age indexes[bone age index(BAI),bone age difference(BAD)]were detected with the same instrument at the same place.The fasting venous blood was collected to detect levels of serum IGF-1,IGFBP-3 and BAP by enzyme-linked immunosorbent assay.The abundances of intestinal floras were monitored by 16s rDNA high-throughput sequencing technology combined with bioinformation analysis technology.A total of 40 healthy children during the same period were enrolled as control group,and differences in different indexes within the same groups or between the two groups were compared by independent sample t test or paired t test.The correlation between abundances of intestinal floras and levels of serum IGF-1,IGFBP-3 and BAP was analyzed by Pearson correlation analysis.Results Compared with the control group.the height,weight,BAD,BAI,levels of serum IGF,IGFBP-3 and BAP,Chaol,Shannon and Pielou e of ISS patients decreased before treatment,and the differences were statistically significant(t=7.119～44.143,all P<0.05).After treatment,height,weight,BAD,BAI,levels of serum IGF,IGFBP-3 and BAP,Chaol,Shannon and Pielou e were increased in ISS children(t=3.145～39.188),the above indexes were still lower than those in control group(t=2.389～69.893),the differences were statistically significant(all P<0.05),respectively.In intestinal floras,dominant bacterial groups at phylum level were Firmicutes,Bacteroidetes,Actinobacteria and Proteobacteria,while dominant bacterial groups at genus level were Blautia,Bifidobacterium,Faecalibacterium and Bacteroides.Compared with the control group,before treatment,the abundances of Actinobacteria and Proteobacteria increased in the ISS group,while the abundances of Bacteroidetes,Bifidobacteria and Bacteroides decreased,and the differences were statistically significant(t=25.224～46.345,all P<0.05).After treatment,abundances of Bacteroidetes,Bifidobacterium and Bacteroides in the ISS group increased compared to before treatment,while abundance of Proteobacteria decreased,and the differences were statistically significant(t=10.055～39.245,all P<0.05).The abundances of Bacteroidetes,Bifidobacterium and Bacteroides in ISS group were lower than those in control group,while abundance of Proteobacteria was higher than that in control group,and the differences were statistically significant(t=6.290～20.540,all P<0.05).The abundances of Bacteroidetes,Bifidobacterium and Bacteroides were positively correlated with levels of serum IGF-1,IGFBP-3 and BAP(r=0.300～0.759,all P<0.05).Conclusion The abundances of intestinal floras are decreased,and the structure is abnormal in children with ISS.The abundances of beneficial bacteria in intestinal floras are related to levels of serum IGF-1,IGFBP-3 and BAP.In clinical treatment of ISS,combined treatment with intestinal flora disorders may be conducted.

Objective To review the application scope of risk communication based on eHealth technology in the primary prevention of cardiovascular diseases,so as to provide references for future research and application.Methods A systematic search was conducted in PubMed,Cochrane Library,Embase,Web of Science,CINAHL,PsycINFO,CNKI,Wanfang database,and SinoMed.The search time limit was from the establishment of databases to March 1,2024.The included literature was summarized and analyzed.Results A total of 24 articles were included.The forms of eHealth technology applied in risk communication for primary prevention of cardiovascular include online websites,computerized decision support systems,electronic health records,mobile applications,email,telephone,and text messages.The functions include risk assessment,risk notification,personalized advice,risk tracking and reminders.The outcome indicators include risk perception,physiological indicators,lifestyle and behavior,psychological indicators,feasibility evaluation,decision correlation,doctor-patient communication,intention,risk score,and physician drug prescription.Conclusion The use of eHealth technology in risk communication of cardiovascular diseases has potential value in improving patients'risk perception and promoting healthy behaviors.It is necessary to continuously improve the functions of eHealth technology and enhance its precision and intelligence,so as to better meet the needs of medical staff and patients and promote the efficient implementation of primary prevention of cardiovascular diseases.

Objective:To evaluate the effect of sex factors on rewarming in patients with mild hypothermia undergoing lithotripsy for urolithiasis.Methods:In this prospective study, 100 American Society of Anesthesiologists Physical Status classification Ⅰ or Ⅱ patients, aged 18-60 yr, with a body mass index of 18-30 kg/m 2, scheduled for elective lithotripsy for urolithiasis, were divided into 2 groups ( n=50 each) based on sex: male group (group M) and female group (group F). The rewarming measures were as follows: the room was preheated, maintaining a constant temperature of 22-24 ℃, all the patients were covered with medical heating blanket under their bodies, and the inflatable heating apparatus was placed on the surface quilt, and the air supply was placed near the lower limbs of the patients. The parameters were set as follows: temperature 40 ℃, strong wind. If the patients complained of heat, the temperature parameter settings were changed, and the quilt was removed when necessary. If the patients complained of cold, blood transfusion and infusion heating instrument were added, medical heating blanket was turned on, or an anther quilt was used. Body temperature and the number of patients with successful rewarming were recorded on admission to post-anesthesia care unit (T 0) and at 10, 30, 45 and 60 min after rewarming (T 1-4), and at 1, 3 and 5 h after returning to the ward (T 5-7). The comfort scores were assessed while measuring body temperature at T 0 and T 4, and the occurrence of shivering, hypertension, hypotension and arrhythmias was observed. Results:Compared with group F, the body temperature was significantly increased at T 3 and T 4, the success rate of rewarming and incidence of shivering were increased at T 3 ( P<0.05), and no significant change was found in the incidence of hypertension, hypotension and arrhythmias in group M ( P<0.05). Conclusions:Sex factors affect rewarming outcomes in patients with mild hypothermia undergoing lithotripsy for urolithiasis. Females exhibit a slower rewarming rate and less shivering than males.

Objective To explore the correlation between serum insulin-like growth factor1(IGF-1),insulin-like growth factor binding protein3(IGFBP-3),bone-specific alkaline phosphatase(BAP)and abundance of intestinal flora in children with idiopathic short stature(ISS).Methods A total of 86 children with ISS who were treated with short-acting recombinant growth hormone for the first time in Department of Endocrinology of Baoding Hospital,Beijing Children's Hospital,Capital Medical University,were enrolled from July 2021 to June 2023.Before treatment and at 6 months after treatment,physical indexes(height,weight)and bone age indexes[bone age index(BAI),bone age difference(BAD)]were detected with the same instrument at the same place.The fasting venous blood was collected to detect levels of serum IGF-1,IGFBP-3 and BAP by enzyme-linked immunosorbent assay.The abundances of intestinal floras were monitored by 16s rDNA high-throughput sequencing technology combined with bioinformation analysis technology.A total of 40 healthy children during the same period were enrolled as control group,and differences in different indexes within the same groups or between the two groups were compared by independent sample t test or paired t test.The correlation between abundances of intestinal floras and levels of serum IGF-1,IGFBP-3 and BAP was analyzed by Pearson correlation analysis.Results Compared with the control group.the height,weight,BAD,BAI,levels of serum IGF,IGFBP-3 and BAP,Chaol,Shannon and Pielou e of ISS patients decreased before treatment,and the differences were statistically significant(t=7.119～44.143,all P<0.05).After treatment,height,weight,BAD,BAI,levels of serum IGF,IGFBP-3 and BAP,Chaol,Shannon and Pielou e were increased in ISS children(t=3.145～39.188),the above indexes were still lower than those in control group(t=2.389～69.893),the differences were statistically significant(all P<0.05),respectively.In intestinal floras,dominant bacterial groups at phylum level were Firmicutes,Bacteroidetes,Actinobacteria and Proteobacteria,while dominant bacterial groups at genus level were Blautia,Bifidobacterium,Faecalibacterium and Bacteroides.Compared with the control group,before treatment,the abundances of Actinobacteria and Proteobacteria increased in the ISS group,while the abundances of Bacteroidetes,Bifidobacteria and Bacteroides decreased,and the differences were statistically significant(t=25.224～46.345,all P<0.05).After treatment,abundances of Bacteroidetes,Bifidobacterium and Bacteroides in the ISS group increased compared to before treatment,while abundance of Proteobacteria decreased,and the differences were statistically significant(t=10.055～39.245,all P<0.05).The abundances of Bacteroidetes,Bifidobacterium and Bacteroides in ISS group were lower than those in control group,while abundance of Proteobacteria was higher than that in control group,and the differences were statistically significant(t=6.290～20.540,all P<0.05).The abundances of Bacteroidetes,Bifidobacterium and Bacteroides were positively correlated with levels of serum IGF-1,IGFBP-3 and BAP(r=0.300～0.759,all P<0.05).Conclusion The abundances of intestinal floras are decreased,and the structure is abnormal in children with ISS.The abundances of beneficial bacteria in intestinal floras are related to levels of serum IGF-1,IGFBP-3 and BAP.In clinical treatment of ISS,combined treatment with intestinal flora disorders may be conducted.

[Objective]To assess the intercultural communication competence of college students majoring in traditional Chinese medicine(TCM)and analyze the influencing factors.[Methods]Using the stratified convenience sampling method,a number of students majoring in TCM from three medical colleges were selected and asked to fill in the Chinese College Students' Intercultural Competence Assessment Scale.Also gathered was the demographic information of the respondents,including gender,grade,specialty,parents' education level,family residence,English proficiency and international exchange experience,etc.Next,these data were subjected to exploratory factor analysis,confirmatory factor analysis,t-tests,one-way ANOVA and correlation analysis to measure the impact of these factors on the intercultural communication competence of the students.[Results]A total of 464 valid questionnaires were collected.The questionnaire demonstrated good reliability and validity,with the six dimensions explaining a cumulative variance of 78.901％,the Cronbach's alpha values for all dimensions were greater than 0.8,and significant correlations were found between each pair of dimensions(P＜0.05).The study showed that the intercultural communication competence of students majoring in TCM was insufficiently comprehensive.Based on the descending order of means,the dimensions ranked as follows:knowledge A(4.791±0.936),attitude(4.593±1.074),awareness(4.182±1.028),skill A(3.931±0.992),skill B(3.843±1.035)and knowledge B(3.252±0.989).Significant differences were found in the related dimensions of intercultural communication competence based on various demographic factors(P＜0.05).[Conclusion]There's a structural imbalance between knowledge acquisition and skill application in the intercultural communication competence of TCM undergraduates,and the core influencing factors lie in international exchange experience,English proficiency,etc.Constructing a three-dimensional training system of"knowledge-skills-practice"may help improve the intercultural communication competence of college students and promote the internationalization of higher education in TCM.

[Objective]To assess the intercultural communication competence of college students majoring in traditional Chinese medicine(TCM)and analyze the influencing factors.[Methods]Using the stratified convenience sampling method,a number of students majoring in TCM from three medical colleges were selected and asked to fill in the Chinese College Students' Intercultural Competence Assessment Scale.Also gathered was the demographic information of the respondents,including gender,grade,specialty,parents' education level,family residence,English proficiency and international exchange experience,etc.Next,these data were subjected to exploratory factor analysis,confirmatory factor analysis,t-tests,one-way ANOVA and correlation analysis to measure the impact of these factors on the intercultural communication competence of the students.[Results]A total of 464 valid questionnaires were collected.The questionnaire demonstrated good reliability and validity,with the six dimensions explaining a cumulative variance of 78.901％,the Cronbach's alpha values for all dimensions were greater than 0.8,and significant correlations were found between each pair of dimensions(P＜0.05).The study showed that the intercultural communication competence of students majoring in TCM was insufficiently comprehensive.Based on the descending order of means,the dimensions ranked as follows:knowledge A(4.791±0.936),attitude(4.593±1.074),awareness(4.182±1.028),skill A(3.931±0.992),skill B(3.843±1.035)and knowledge B(3.252±0.989).Significant differences were found in the related dimensions of intercultural communication competence based on various demographic factors(P＜0.05).[Conclusion]There's a structural imbalance between knowledge acquisition and skill application in the intercultural communication competence of TCM undergraduates,and the core influencing factors lie in international exchange experience,English proficiency,etc.Constructing a three-dimensional training system of"knowledge-skills-practice"may help improve the intercultural communication competence of college students and promote the internationalization of higher education in TCM.

Objective:To summarize the clinical features of primary segmental volvulus (PSV) in neonates.Methods:A retrospective analysis was conducted on the clinical data of neonates with PSV who were admitted to the Department of Neonatal Surgery, Children's Hospital Affiliated to Capital Institute of Pediatrics from May 2014 to May 2023. The clinical manifestations, auxiliary examinations, treatment and prognosis of the neonates were summarized, and descriptive statistical analysis was performed on the collected data.Results:A total of 10 neonates with PSV were included, with a mean gestational age of (34.1±3.0) weeks and birth weight of (2 291±646) g. Eight cases had an onset age of 3 d or less, and 2 cases had an onset age of more than 3 d. Abdominal distension was observed as the main manifestation in all cases, while bilious vomiting occurred in seven cases and hematochezia in five cases. Imaging examinations mainly revealed low intestinal obstruction without specific manifestations. Laboratory tests showed metabolic acidosis and varing degrees of anaemia. Nine cases underwent diagnostic abdominal puncture, of which five had bloody ascites, two had clear ascites, one had bloody mixed with fecal-like ascites, and one had chylous ascites. All the cases underwent emergency exploratory laparotomy and segmental small bowel resections with either primary intestinal anastomosis or enterostomy. All cases were successfully cured and had been followed up to the age of 4 months to 9 years with good growth and development as normal children of the same age.Conclusions:Neonatal PSV is an independent abdominal emergency characterized by non-specific clinical manifestations and difficult preoperative diagnosis, but the overall prognosis is favorable after active surgical treatment.

Objective·To investigate the intervention effect of oral motor training combined with pediatric tui-na on feeding intolerance in preterm infants to provide new treatment options and improve the quality of care.Methods·By using a non-simultaneous controlled clinical trial method,75 eligible preterm infants from the neonatal unit of a tertiary care hospital in Jinan were selected as the experimental group to implement oral training combined with pediatric massage therapy.Another 60 preterm infants admitted in 2020 were selected as the control group,who had already received oral motor training but had not received pediatric massage.The experimental group was treated for 7 d and the efficacy of the two groups was compared.Comparisons between the two groups included signs of feeding intolerance such as vomiting,gastric remnants and other outcome indicators such as first oral feeding time,gastric tube retention time,increased milk volume at day 3 and increased milk volume at day 7,feeding initiation time,increased weight at day 3 and increased weight at day 7,recovery time of birth weight,and days of hospitalization in both groups.Results·The differences in gender,age,birth weight,and Apgar score between the two groups before treatment were not statistically significant(P>0.05)indicating comparability.After treatment,preterm infants in the experimental group showed significant improvement in feeding performance,first oral feeding time,gastric tube retention time,increased milk volume at day 3 and increased milk volume at day 7,increased weight at day 3 and increased weight at day 7,hospitalization days and other observed indexes compared with the control group,and the differences were statistically significant(P<0.05).There was no significant difference in the feeding initiation time and recovery time of birth weight between the two groups(P>0.05).Conclusion·The combined application of oral motor training and pediatric tui-na is significantly more effective than single oral motor training in the short-term treatment of feeding intolerance in preterm infants.This combination therapy helps preterm infants to increase milk intake and accelerate weight gain,helps the children to recover intestinal function,establishes early nutritional support,promotes growth and development,and reduces the risk of long-term complications.This treatment is simple,safe and efficient,and has the value of popularization.