1.Correlation of incidence of dysentery in Shaanxi province and Yunqi theory
China Journal of Traditional Chinese Medicine and Pharmacy 2005;0(11):-
Dysentery is one of the digestive system diseases, which has a higher incidence rate. The aim of present study was to further explore the incidence of dysentery and get the better prevention of this disease. The data were collected and statistically analyzed from Shaanxi Province for the monthly incidence of dysentery in 22 years. In addition, according to the Yunqi theory and related incidence of diseases, the correlation between the incidences of dysentery and Suiyun, Sitian, Zaiquan and Six-qi were summarized systematically. This study provides a reference for the incidence of dysentery.
2.Comparative Study of the Efficacies of Warm Needling Versus Salt Moxibustion in Treating Knee Osteoarthritis
Jingming DENG ; Ying CHEN ; Shengxu WANG
Shanghai Journal of Acupuncture and Moxibustion 2015;(3):243-245
Objective To compare the clinical efficacies of warm needling versus salt moxibustion in treating knee osteoarthritis. Methods One hundred and twenty patients with knee osteoarthritis were randomly allocated to groupsⅠ andⅡ, and control group, 40 cases each. GroupⅠ received salt moxibustion; groupⅡ, warm needling; the control group, routine medication. After 4 weeks of treatment, the Lysholm Knee Scoring Scale scores, the VAS scores, the quality of life scores and the clinical therapeutic effects were compared between the three groups.Results There were statistically significant pre-/post-treatment differences in the Lysholm Knee Scoring Scale scores, the VAS scores and the quality of life scores in the three groups (P<0.05). There were statistically significant post-treatment differences in the Lysholm Knee Scoring Scale scores and the VAS scores between groupⅠ orⅡ and the control group (P<0.05). The total efficacy rate was 90.0% in groupⅠ, 87.5% in groupⅡ and 70.0% in the control group. There was a statistically significant difference in total efficacy rate between groupⅠ orⅡ and the control group (P<0.05).Conclusions Warm needling and salt moxibustion are both effective way to treat knee osteoarthritis and have equal therapeutic effects.
3.Development of electronic inpatient satisfaction questionnaires
Lijun ZHANG ; Pingyan CHEN ; Jingming WANG
Chinese Journal of Hospital Administration 1996;0(07):-
Objective To develop electronic touch-screen inpatient satisfaction questionnaires so as to improve the real-fimeness and accuracy of data processing in patient satisfaction surveys and evaluations. Methods 266 inpatients from 20 clinical departments of a certain hospital in Zhangjiakou were asked to make satisfaction evaluations via a touch screen and the reliability and validity of the questionnaires were assessed by statistical and psychological means. Results The item response rate was 98.72%, the effective rate was 98.1%, and the a reliability coefficient for internal consistency was 0.9474; the composition of the questionnaires, which matched the reality of management, supported contents validity; a factor analysis showed that the factor load and structure, which matched the structure of the questionnaires, supported structure validity; intra-factor correlations, which were stronger than interfactor correlations, supported aggregation and discrimination validity. Conclusion The questionnaires, reliable andvalid, interface friendly and easy to operate, facilitate their use by patients with different backgrounds. The real-time occurrence and antomatic pooling of survey data render possible the automation of data collection in patient satisfaction surveys and evaluations.
4.Treatment of sagittal maxillary fractures
Jingming LIU ; Weiqiao ZHU ; Zhiyuan CHEN
Journal of Practical Stomatology 2000;0(05):-
Objective:To evaluate the technique of reduction and rigid internal fixation of sagittal maxillary fracture. Methods:15 cases of sagittal maxillary fracture were reviewed. Occlusal guide plates were prepared preoperatively by model surgery analysis in 10 cases; Le Fort ? osteotomy and down-fracture were done in 8 cases; Pterygomaxillary junctions were also separated in the other cases. Internal fixation was applied along the anterior maxillary surface by using microplates in all 15 cases. Results:Anatomically reduction was achieved in all cases; Occlusion of 14 cases was corrected except one case of fracture re-displaced. Conclusion:Orthognathic technique is effective treatment of sagittal maxillary fracture; One microplate applied along anterior maxillary surface may be not enough to ensure the fixation of sagittal maxillary fracture.
5.Analysis of 114 cases of orbital fractures
Weiqiao ZHU ; Jingming LIU ; Zhiyuan CHEN
Journal of Practical Stomatology 2000;0(05):-
Objective: To investigate the principle of diagnosis and treatment of orbital fracture. Methods:114 cases of orbital fractures were reviewed. The incidence of major clinical feature was estimated and the surgical procedures were analyzed. Results:Incidence rate of restricted ocular motility, diplopia and enophthalmos were 63.2%, 62.3% and 59.6% respectively; The incidence of optic nerve injury, lacrimal injury and rupture of the globe was 15.8%,15.8% and 12.3% respectively. 95.6% of the cases were undergone orbital wall reconstruction (artificial bone graft) and 72.8% were received fracture reduction and internal fixation. Conclusion:Restricted ocular motility, diplopia and enophthalmos are major symptoms of orbital fracture and optic nerve injury, lacrimal injury and rupture of the globe are important complications of orbital fracture; Orbital reconstruction is the most popular surgical procedure for orbital fracture and bone reduction and internal fixation is also need for impure orbital fracture.
6.Surgical repair of medial orbital wall combined with orbital floor fracture via lower lid subciliary approach
Zhiyuan CHEN ; Jingming LIU ; Weixian SONG ; Jun ZHOU
Ophthalmology in China 2006;0(06):-
Objective To assess the effect of surgical repair of medial orbital wall combined with orbital floor fracture via lower lid subciliary approach. Design Retrospective case series. Participants 18 cases of medial orbital wall combined with orbital floor fracture. Methods All patients underwent the reconstruction of orbital wall via lower lid subciliary approach. The composite hydroxyapatite was implanted into the surface of medial orbital wall and orbital floor after lacriminal cyst was completely dissected and protected during the operation. Orbital axial and coronal CT, three-dimension CT scan have been used in all the cases preoperalively and postoperatively. Preoperative CT was compared with postoperative CT. Main Outcome Measures Clinical symptoms and complications. Results All patients were followed up for 3 to 18 months. The postoperative scar of infracillary skin was not obvious. The composite hydroxyapatite was not rejected and dislocated in all cases postoperatively. No postoperative epiphora was found in either case. Preoperative diplopia and enophthalmos were corrected. Conclusion The treatment of medial orbital wall combined with orbital floor fracture via an isolated lower lid subciliary approach was feasible. But the incision was only used in the treatment of inferior medial orbital wall combined with orbital floor fracture, especially the transition area fracture between the orbital floor and medial orbital wall.
7.Fc receptor like 3 in Han nationality of Anhui patients with rheumatoid arthritis
Daoqian SANG ; Zhijun LI ; Linjie CHEN ; Jingming DUAN
Chinese Journal of Rheumatology 2010;14(2):123-127
Objective To investigate the association between a few single nucleotide polymorphisms (SNPs)in Fc receptor like 3(FcRL3)and rheumatoid arthritis(RA)in Han nationality of Anhui patients.Methods One hundred and forty RA patients along with one hundred and eighty-seven healthy controls were included in the study.SNPs of FcRL3-1(rs0158440),FcRL3-2(rs2225828),FcRL3-3(rs7528684).FcRL34(rs11284799),FcRL3-5(rs945635),FcRL3-6(rs3761959),FcRL3-7(rs2210913),FcRL3-8(rs2282284)and FcRL3-9(rs2282283)in the FcRL3 gene were genotyped by MALDI-TOF technology.Haplotypes were estimated using PHASE v 2.1 software.Results The frequency of FcRL3-3-1 69C alleles in RA patients was significantly increased compared with healthy controls(X~2=7.348,P=0.007,OR=1.558,CI:1.130~2.150).The decreased compared with healthy controls.ConclusionFcRL3 may be associated with RA susceptibility in Anhui Han population.
8.Intervention of Zhuanggu granule on IL-1β and TNF-α level of the patients with osteoarthritis
Jixiao LANG ; Dexi CHEN ; Peilin YU ; Jingming ZHAO ; Zhijun XING
International Journal of Traditional Chinese Medicine 2010;32(5):400-401
Objective To investigate the influence of Zhuanggu granule on the concentration of IL-1β and TN-F-α in knee cavity of patients with knee degenerated osteoarthritis. Methods A total of eighty patients with knee degenerated osteoarthritis were recruited into a Zhuanggu granule group (30 cases), a Sulphuric acid Glucosamine group (15 cases) and a Sodium Hyaluronate group (15 cases) according to Doll grouping method. After all groups were treated for 4 weeks, the changes of concentration of IL-1β and TNF-α was detected before and after the therapy Results After the treatment, the concentration of IL-1β and TNF-α in Zhuangu granule group was significantly lower than the other two groups (Sodium Hyaluronate and sulphuric Glucosamine group). Conclusion Zhuangu Granule could influence the concentration of IL-1β and TNF-α in patients of knee degenerated osteoarthritis.
9.Lignan constituents and activities of Linum usitatissimum L. above ground
Xiang CHEN ; Jingming JIA ; Yu YANG ; Nengjiang YU
Journal of International Pharmaceutical Research 2017;44(6):590-594
Objective To investigate the chemical constituents and activities of Linum usitatissimum L.aboveground. Meth-ods The chemical constituents were separated through silica gel,ODS,Sephadex LH-20,and semi-preparative RP-HPLC chroma-tography and identified by optical rotation and spectroscopic analysis. All of the isolates were evaluated for their inhibitory activities by the luciferase assay. Results Eight dibenzylbutyrolactone lignans were separated from L. usitatissimum and identified as(-)-hinoki-nin(1),(-)-bursehernin(2),(-)-dimethylmatairesinol(3),(-)-yatein(4),(-)-thujaplicatin trimethyl ether(5),nemerosin (6),(+)-E-7,8-dehydromatairesinol dimethyl ether(7),and E-7,8-dehydrothujaplicatin trimethyl ether(8),respectively. Conclu-sion Compounds 7 and 8 were isolated from L. usitatissimum for the first time,and NMR spectral data of compound 8 were reported for the first time. Compounds 1 and 3 showed moderate inhibitory activities on IL-6/STAT3 signaling pathway with IC50 values of 42.12 and 43.43μmol/L,respectively.
10.Relative tolerance of lung in murine model of acute graft-versus-host disease
Xiaoli XU ; Zhuowen CHEN ; Jingming LI ; Ping ZOU
Chinese Journal of Organ Transplantation 2016;37(7):427-432
Objective To analyze the immune privilege of lung in acute graft-versus-host disease (aGVHD).Methods The models of aGVHD were established,and C57BL/6J→C57BL/6J model was used as control.The clinical scores and survival were observe& The pathological injuries were compared between the lung and traditional target organs (liver,small intestines and skin).The expression of IFN-γ in different organs after transplantation was detected by ELISA.Results Allogeneic hematopoietic stem cell transplantation (HSCT) mice had high 42-day survival rate (20 %) post-transplantation,and recipients of allogeneic grafts showed classical symptoms and histological injury,and pathological changes of lung were not as serious as the liver,small intestine,skin at day 28 after transplantation.Syngeneic mice all survived at day 42 after transplantation,without GVHD symptoms and pathological changes.The mice in MHC-disparate mice (2 ∶ 1 and 4 ∶ 1 groups) died significantly faster at a median of 12 days after transplantation,with severe changes of clinical symptoms and pathology of classical organs,and MHC-disparate mice (4∶1 groups) had developed severe interstitial pneumonitis.The mean IFN-γ concentration in the lung of allogeneic HSCT mice was obviously increased in the first and second week after transplantation,the IFN-γ concentrations of target organs (liver,small intestines,skin) were slightly increased in the first and second week after transplantation,and there were statistically significant difference from lung (P<0.05).Condmion There wasrelativeimmune privilege of lung in a murine model of aGVHD induced by HSCT,which was associated with the expression of MHCin the mice and IFN-gamma of lungs after transplantation.