1.Effects of ?-1bIFN on Hepatitis Gravis Reconvalescent
China Pharmacy 1991;0(01):-
OBJECTIVE:To probe into the effects of ?-1bIFN on the development process from the hepatitis gravis to postnecrotic cirrhosis.METHODS:The change of serum liver fibrosis markers and hepatic function were observed in treatment group and control group before and after treatment.RESULTS:(1)In treatment group,all the serum liver fibrosis markers were decreased after treatment and were significantly different from those in control group(P0.05).(2)After treatment,the levels of serum albumin,globulin and count of platelet reverted to normal in treatment group and the levels were significantly different from those in control group(P
2.Drug Consultation Records in Our Hospital:Retrospective Analysis of 1663 Cases
China Pharmacy 2007;0(35):-
OBJECTIVE:To improve the quality of drug consultation.METHODS:The drug consultation records of a total of 1 663 cases in our hospital from July 2004 to July 2007 were analyzed statistically by a retrospective method.RESULTS:Of the drug consultation records of a total of 1 663 cases,the chief questions consulted were adverse drug reactions and long-term medication safety(25.2%),dosage and administration(21.1%),medication for special populations(9.7%),drug interactions(8.1%),pharmacological action and indications(7.1%),and generic name and composition of drugs(5.2%).CONCLUSION:The drug consultation service in our hospital achieved a remarkable efficacy in guiding physicians and pharmacists on rational drug use;however,it has its problems and remains to be improved further.
3.Systematic Review of Diammonium Glycyrrhizinate in the Treatment of Drug-induced Liver Injury
China Pharmacy 2001;0(12):-
OBJECTIVE: To evaluate the efficacy and safety of diammonium glycyrrhizinate in the treatment of drug-induced liver injury according to present clinical studies. METHODS: Retrieved from CBM and the CNKI from 1994 to 2009, literatures about the randomized controlled trials that the effective rate of diammonium glycyrrhizinate was compared with that of other hepatoprotective with drug-induced liver injury and drug-induced liver disease as study subjects. RESULTS: 18 RCTs including 1,644 patients with drug-induced liver injury were enrolled. The effective rate of diammonium glycyrrhizinate group was higher than that of control group, statistical significance was noted in two groups (P
4.Effects of Functional Electrical Stimulation on Spastic Diplegia:Surface Electromyography Study
Chinese Journal of Rehabilitation Theory and Practice 2008;14(3):247-248
Objective To value the application of surface electromyography(sEMG)in assessing the functional electrical stimulation(FES)used in children with spastic diplegia.Methods 20 children with spastic diplegia were treated with FES.They were assessed with the sEMG and the clinical assessment before and after treatment.Results After treatment,the iEMG of the biceps brachii and quadriceps decreased significantly on the functional position,but increased significantly when the muscles contracted.Conclusion FES can reduce the spasticity and increase the strength of the limbs in children with spastic diplegia.The sEMG can be used as an objective assessment tool.
5.The Preliminary Study on the Construction of Medical Device Naming System in China.
Wanjuan YANG ; Jun LI ; Jingli LI
Chinese Journal of Medical Instrumentation 2015;39(6):442-444
The article has summarized the situation related to medical device naming, analyzed the problems of medical device naming in our country, put forward some new thinking in building the naming system of medical device in our country provided some reference on technical study of medical device naming.
China
;
Durable Medical Equipment
;
classification
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Terminology as Topic
6.The Analysis on Application of Global Medical Device Nomenclature(GMDN).
Wanjuan YANG ; Jun LI ; Jingli LI
Chinese Journal of Medical Instrumentation 2015;39(4):275-278
The article has reviewed the administration technical structure and global application of the global medical device nomenclature(GMDN), analyzed the coordination between GMDN and the industry status of medical device in our country, put forward some suggestions on the applicaition of GMDN, provided some reference on raising the management level of medical device in our country.
Equipment and Supplies
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standards
;
Terminology as Topic
7.Progress in FDA UDI System for Medical Devices and its Revelation for Coding of our Country
Wanjuan YANG ; Jun LI ; Jingli LI
China Pharmacist 2015;(1):142-144,145
USA is the first country implementing the UDI program at national level,and the UDI rules and GUDID guidance have been issued by FDA recently to officially launch the implementation of UDI. The paper reviewed the advancement of UDI program,dis-cussed the framework of UDI system,analyzed the approaches of UDI implementation such as accredited issuing agencies and GUDID et al, and made some suggestions on the development of medical device coding system in our country.
8.Aescine in treatment of lumbar intervertebral disc prolapse
Jingli ZHAO ; Cai LI ; Xueying BAI
Chinese Journal of New Drugs and Clinical Remedies 2001;20(3):163-164
AIM:To observe the therapeutic effect of aescine in the treatment of lumbar intervertebral disc prolapse(LIDP).METHODS:One hundred and seventy-six patients with LIDP were divided into 2 groups:aescine group of 80 patients[M56,F24;age(43±s17)a,course of disease(7.4±2.3) mo] received conventional therapy plus aescine 10-15 mg in 5 % glucose or 0.9 % sodium chloride injection 250 mL,iv,drip,bid,for 7-10 d.Control group of 96 patients[M57,F39;age(42±16)a,course of disease(7±3)mo]only received conventional therapy,including towing,massage,acupuncture,anodyne.Therapeutic effects of both groups were compared after 4 wk.RESULTS:The total effective rate of aescine and control group was 95 % and 81 %,respectively(P<0.05),while in those course of disease less than 0.5 a the effective rate was 97 % and 85 %,respectively(P<0.05).No obvious adverse reactions occoured. CONCLUSION:Aescine is safe and effective for the treatment of LIDP.The shorter the disease course is,the better the therapeutic effects are.
9.Effect of WenyangHuoxueFang on expression of MMP-3 and TIMP-1 in kidney of rats with unilateral ureteral obstruction(UUO)
Wei CAO ; Jun LI ; Jingli SHI
China Journal of Traditional Chinese Medicine and Pharmacy 2005;0(03):-
Objective: To observe the protective effect of WenyangHuoxueFang on renal interstitial fibrosis in rats and try to explore the mechanism.Methods: The renal obstruction model of rats was established by unilateral ureteral obstruction(UUO) ,and then they were divided into four groups randomly,including UUOW group(treated with WenyangHuoxueFang),UUOF group(treated with Fosinopril),UUO group and the sham-operation group.The morphological changes of kidney tissue were observed,the level of RBP was detected by ELISA,the expression of MMP-3 and TIMP-1 was detected by immuno-histochemistry.Results: Compared with the sham-operation group,there were different degrees of kidney lesions in UUO group and the treatment groups.The level of RBP in UUO group was significantly higher than that in sham-operation group.Compared with UUO group,the RBP expression in UUOF group and UUOW group was significantly lower(P0.05).The expressions of MMP-3 and TIMP-1 in UUO group were increased,and the amplitude of increasing expression of TIMP-1 was higher than that of MMP-3.The treatment groups had higher expression of MMP-3(P
10.Construction of c-myc RNA Antisense Expression Plasmid and Its Effects on the Malignant Phenotype of HL60 Cell Line
Yinxiong LI ; Muzhen FAN ; Jingli ZHANG
Chinese Journal of Cancer Biotherapy 1994;0(01):-
The inducible c-myc antisense RNA expression plasmid PGXC expressed in mammalian cells was constructed. PGXC was cotransferred with plasmid pSV2neo which confers resistance to Geneticin (G418) to human promyclocytic leukemia cell line HL60. Following the promotion of c-myc antisense RNA expression with Cd~(2+) the growth rate of transfectant HL_(60)~R-9 was significantly slower than that of the parent cells HL60. Flow cytometric analysis indicated a marked increase in Gl fraction and decrease in S-phase population in the cell cycle of transfectants. The differentiation of cellular morphology and function of HL_(60)~R-9 was induced. HL_(60)~R-9 did not form colonies on soft agar and had reduced or lost the tumorigenicity in nude mice.