1.Surgical Treatment of Obstructive Jaundice Caused by Bile Duct Strictures after Hepatic Transcatheter Arterial Chemoembolization
Zhenyu JIANG ; Jinghui ZHU ; Liping CAO
Acta Medicinae Universitatis Scientiae et Technologiae Huazhong 2014;(4):441-443,448
Objective To examine the surgical treatments for obstructive jaundice caused by bile duct strictures after hepat-ic transcatheter arterial chemoembolization(TACE).Methods Clinical data were retrospectively analyzed of 9 patients who de-veloped bile duct strictures among 229 patients after TACE between June 1994 and March 2011 in People’s Hospital of Zhe-jiang Provincial and the Second Affiliated Hospital of Zhejiang University.There were 6 cases of primary liver cancer,and 3 ca-ses of metastatic liver cancer.Obstructive jaundice occurred 5 to 16 months after TACE treatment.The median time was 8 months.Results All the nine patients with bile duct strictures suffered different degrees of obstructive j aundice,which was cured after surgical operations or PTC + stenting in 7 patients and significantly relieved by percutaneous transhepatic cholangic drainage(PTCD)in 2 ones.Two patients with obstructive j aundice after TACE for primary liver cancer were followed up for 3 years,and no recurrence of hepatic carcinoma and bile duct obstruction was found.The other 7 patients were followed up for 3 to 13 months,and they all died of deterioration of primary disease.Conclusion Patients with obstructive jaundice caused by bile duct strictures after TACE benefit from surgical operations or intervention treatment.Different surgical strategies are selected based on the characteristics of primary disease,the site and extent of bile duct stricture.
2.Clinical effect of aluminum phosphate gel combined with omeprazole in the treatment of peptic ulcer
Qunhong SHEN ; Jinghui ZHU ; Mengli LUO
Chinese Journal of Biochemical Pharmaceutics 2017;37(3):210-212
Objective To study curative efficacy of aluminum phosphate gel combined with omeprazole in treatment of peptic ulcer and its effects on Gas, TGF-αlevels.Methods 80 patients of peptic ulcer who received therapy from April 2015 to April 2016 in our hospital were selected as research objects.According to random number table, those patients were divided into the observation group and the control group, 49 patients in each group.the control group was treated with omeprazole, while the observation group was treated with aluminum phosphate gel combined on the basis of control group.Then Transforming growth factor, adverse reaction and curative effect were compared.Results After treatment, the serum levels of Gas and TGF-αin both groups were improved (P<0.05); Two weeks after treatment,the level of GAS in the observation group were lower than those in the control group(P<0.05), TGF-αlevel was higher than that in control group(P<0.05); The total incidence of adverse reactions in the observation group was lower than that in the control group(P<0.05); The total effective rate in the observation group was higher than that in the control group(P<0.05). Conclusion Combined use of aluminum phosphate gel and omeprazole in the treatment of peptic ulcer can effectively improve the patient-related serum markers, improve the quality of ulcer healing, significant efficacy, high safety and low incidence of adverse reactions.
3.Mechanism of adverse drug reaction monitoring and reporting at primary level in Yueqing
Jinghui ZHU ; Guilin LIU ; Xianke ZHU ; Qiaoyan ZHU
Chinese Journal of Hospital Administration 2013;29(10):775-779
Compared to the mature monitoring and reporting system of ADRs in developed countries such as the USA and EU,medical institutions in China have played too much a role.Instead,local primary monitoring and reporting system of ADRs should expand their scope of monitoring and reporting,as drug makers,chain drugstores and retailers should develop an effective ADR monitor/report system as well.At present,such a primary system is plagued by insufficient budget and staff,imbalanced urban/rural layout and defective statements.Recommended measures include enhanced surveillance for drug makers,chain drugstores and retailers,for higher reporting ratio of ADRs at primary level; greater publicity and better monitoring and penalty mechanism; better platform for various organizations.
4.Clinical Study on Treatment of Frozen Shoulder by Penetrating Needling with Manipulation
Yaochi WU ; Weimin ZHU ; Congmiao WANG ; Junfeng ZHANG ; Jinghui ZHOU
Journal of Acupuncture and Tuina Science 2008;6(3):173-175
Objective: To observe the clinical effects of frozen shoulder treated by penetrating needling and manipulation Methods: 336 cases of frozen shoulder were randomly divided into treatment group, treated with needling Jianyu (LI 15) toward Jianqian (Ex) and Manipulation, and control group, treated with needling Jianyu (LI 15) toward Jianqian (Ex). The scores of shoulder movement and the changes of infrared image were observed before and after treatment. Results: The therapeutic effects were better in the treatment group than that in the control group (P<0.05). Conclusion: Penetrating needling combining with manipulation is effective in treating frozen shoulder.
5.Development,reliability and validity of the dissociative trait scale
Chengzhi ZHAO ; Xianghua ZHU ; Yaxue WU ; Zhiqiang WU ; Jinghui DUAN ; Zhanjiang LI
Chinese Journal of Behavioral Medicine and Brain Science 2011;20(1):79-81
Objective To develop the Dissociative Trait Scale(DTS),and examine its reliability and validity. Methods Based on literature and research work,a preliminary questionnaire was designed to measure dissociative trait. 1306 college students completed the DTS and Symptom Checklist 90(SCL-90). Results Exploratory factor analysis extracted eight factors. The percentage of variance explained was 57.69%. The Cronbach α-coefficient of the total scale and the eight subscales ranged from 0. 830 ~ 0. 969, the test-retest reliability ranged from 0.575 ~ 763 (P < 0.01 ). The scores of DTS significantly positively correlated with the scores of SCL-90 (P <0.01 ). Conclusion The DTS has acceptable psychometric quality,and can be applied to assess dissociative traits in Chinese college students.
6.Endoscope with subsidiary incision access for orbital blowout fracture.
Xu ZHU ; Ming LI ; Jian-xin YAO ; Hongcheng HAN ; Shubei REN ; Qiuying CAI ; Jinghui XIE
Chinese Journal of Otorhinolaryngology Head and Neck Surgery 2005;40(8):626-627
Adolescent
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Adult
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Endoscopy
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Ethmoid Sinus
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surgery
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Eyelids
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surgery
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Female
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Humans
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Male
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Middle Aged
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Orbital Fractures
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surgery
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Otorhinolaryngologic Surgical Procedures
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methods
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Young Adult
7.Traditional Chinese medicine constitution types in 127 elderly patients with insomnia: an investigation in communities of Yangpu District, Shanghai.
Chen XIA ; Qunbang ZHU ; Feng HUANG ; Jinghui HUANG ; Hongda CHEN ; Mingjun CHEN ; Wei GU ; Bai LI ; Fanfu FANG ; Liangneng WU
Journal of Integrative Medicine 2012;10(8):866-73
To analyze the distribution of traditional Chinese medicine constitution types in elderly patients with insomnia.
8.Analysis on Plasma Metabolicomics Pathway in Rats with Heart Blood Stasis Syndrome
Jinghui ZHENG ; Yunqiu MO ; Weixiong JIAN ; Guilan NING ; Yaping ZHANG ; Zhihua ZHU ; Zhuo WEI ; Jing HE ; Tiehua WANG
World Science and Technology-Modernization of Traditional Chinese Medicine 2014;(7):1614-1618
This study was aimed to analyze the plasma metabolicomics pathway in rats with heart blood stasis syn-drome. KEGG database was used in the signal pathway analysis. HMDB was used in the analysis of molecular metabolite annotation, enzyme or transporter associated and its related properties. The metPA network software was used in the visualization of metabolite path. The results showed that 9 metabolites involved in 15 metabolic pathways. Among them, the P-value of metabolic pathway of pantothenate and CoA biosynthesis, propanoate metabolism, biosynthesis of unsaturated fatty acids was less than 0.05. It was concluded that the metabolic pathways of pan-tothenate and CoA biosynthesis, propanoate metabolism, biosynthesis of unsaturated fatty acids were involved with the pathological process of rats with heart blood stasis syndrome.
9.Effects of clinical nursing pathways on colorectal cancer patients with colostomy in perioperative period:a Meta-analysis
Chinese Journal of Modern Nursing 2016;22(26):3769-3774
Objective To systematically review the effects of clinical nursing pathways on colorectal cancer patients with colostomy.Methods Studies on the randomized controlled trials (RCT) of clinical nursing pathways on colorectal cancer patients with colostomy were systematically searched in electronic databases including CNKI, VIP, CBM and WANFANG Data. Meta-analysis was performed using RevMan 5. 3 software. Results A total of 16 studies enrolling 1 159 patients (582 in observation group and 577 in control group) were included. The results of the Meta-analysis indicated that patients′satisfaction [RR=1.24, 95 CI%=(1.17,1.32), P<0.01] and self-care ability of patients [RR=1.58, 95 CI%=(1.38,1.82), P<0.01] were significantly higher in observation group than in control group. Average hospitalization time [ SMD=-1. 65, 95 CI%=(-2. 66,-0.65) , P<0.01] , the medical expenses [ SMD=-3.89, 95 CI%=(-6.90,-0.87) , P<0.01] and postoperative complications [RR=0.39, 95 CI%=(0.27,0.55), P<0.01] in observation group were significantly decreased while comparing to control group. The descriptive analysis showed that the mastering of health knowledge in the clinical nursing pathway group were better than those in control group.Conclusions Application effects of clinical nursing pathways are superior to the traditional nursing methods in colorectal cancer patients with colostomy.
10.Application effect of ostomy bag on drainage tube seepage after abdominal operation:a Meta analysis
Jinghui FAN ; Kaimei ZHU ; Liangkun XIONG
Chinese Journal of Modern Nursing 2018;24(1):80-85
Objective To systematically evaluate the effect of ostomy bag on drainage tube orifice seepage after abdominal operation.Methods The databases such as the Cochrane Library,PubMed,Embase, CNKI,VIP database,SinoMed (CBM) and WANFANG database were searched for randomized control trials on the application of ostomy bag on drainage tube seepage after abdominal operation,and the retrieval time was limited from database establishment to 31st November,2016. The meta-analysis was performed by the RevMan 5.3 software.Results Finally 12 articles with a total 627 patients met the inclusion criteria,including 316 patients in the observation group and 311 patients in the control group. The Meta-analysis results showed that using ostomy bag to deal with tube seepage could significantly reduce the average cost [SMD=-5.42,95%CI (-6.32,-4.53),P<0.01] and times of daily dressing change[SMD=-2.78,95%CI (-3.22,-2.34),P<0.01], shorten the healing time of sinus [SMD=-1.63,95%CI (-1.86,-1.40),P<0.01],reduce the incidence of irritant dermatitis [RR=0.13,95%CI (0.06,0.26),P<0.01]. The differences were statistically significant. Conclusions Application of ostomy bag to deal with drainage tube seepageis significantly superior to the traditional nursing method.