1.Clinical-application developments of electrical impedance tomography
International Journal of Biomedical Engineering 2008;31(5):279-283
Electrical impedance tomography(EIT) is a novel medical imaging technique, which was developed in recent 20 years following morphology imaging and structure imaging. With the outstanding advantages of noninvasiveness, functional imaging, and medical image monitoring, EIT has a bright and fascinating future in medical application. This paper reviews the htest development of its clinical appLication both in our country and abroad, including measurement of lung density and air volume, strategy to enhance protective ventilation, breast cancer detection, virtual bladder biopsy, acute stroke imaging,and monitoring of intraperitoneal bleeding, etc.
2.Analysis of Study of Senile Dementia in China
Jun LV ; Yun ZHANG ; Huijiong YU ; Yuan YAN ; Yin LIU ; Min JI ; Heng LI ; Jinghua WU
Chinese Journal of Rehabilitation Theory and Practice 2010;16(6):501-504
ObjectiveTo analyze past study on senile dementia in China, and shape the foundation for constructing social support system for elderly with dementia.MethodsA combination of qualitative and quantitative method was used to analyze 406 literatures related to the elderly with dementia published in China since 2000.ResultsDiagnosis method for the senile dementia has matured; but the causes of the disease is still not clear and there is no thorough remedy; study on early intervention, nursing care and social support are inadequate.ConclusionDiagnostic criteria should be standardized, community screening assessment should be done on a regular basis; etiology based on risk factors should be strengthened; systematic study on intervention should be carried out; training on home care techniques should be enhanced. Resolving the care of the elderly with dementia depends on the social support system construction eventually.
3.Screening Scales for Senile Dementia
Chuanwei FU ; Jun LV ; Yun ZHANG ; Huijiong YU ; Jinghua WU ; Heng LI ; Min JI ; Yin LIU
Chinese Journal of Rehabilitation Theory and Practice 2010;16(6):505-508
ObjectiveTo analyze application of screening and assessment scales for senile dementia in China.MethodsVarieties of screening and assessment scales were found in the studies on screening and assessment of senile dementia in China, as well as their common features and epidemiological results. A combination of qualitative and quantitative methods was used in the analysis.ResultsMini Mental State Examination (MMSE) is preferred tool in screening and Activity of Daily Living Scale (ADL) is the secondary.ConclusionThe future research direction should include: studying the appropriate boundary value in MMSE for China; optimizing the combination of screening scale and developing more appropriate screening tool.
4.Human Resource Status for Rehabilitation Coordinator and Street Administrator of Disability Community Rehabilitation in Shanghai
Wan-chun CHEN ; Min JI ; Heng LI ; Jie XU ; Jianping YANG ; Jinghua WU ; Jun LV
Chinese Journal of Rehabilitation Theory and Practice 2012;18(12):1184-1186
Objective To understand the human resource status of the community rehabilitation management in Shanghai and provide evidence for the construction of this human resource. Methods Census institutions of community rehabilitation management in Shanghai were investigated with self-questionnaire. Results Shanghai has initially established personnel of community rehabilitation management,which contains rehabilitation coordinators and street community administrator. However, the structure and number of the personnel has yet to be improved. Conclusion Personnel building must focused on optimizing the personnel structure of rehabilitation coordinator, moderately expanding the street community administrators, filling the community rehabilitation service gap between city and urban in next stage.
5.Evaluation of Objective Structured Clinical Examination for Clinical Skills in Rehabilitation Therapeutics
Zhihai LV ; Zhimei JIANG ; Wei ZHANG ; Liping WANG ; Yanping FAN ; Lanmin GUO ; Ying SUN ; Jinghua TANG ; Yanan WANG
Chinese Journal of Rehabilitation Theory and Practice 2012;18(3):296-298
Objective To investigate the effect of Objective Structured Clinical Examination (OSCE) on practice examination of RehabilitationTherapeutics. Methods OSCE was applied in graduation practice skills testing of the 2007 classes of Rehabilitation Therapeutics.The design, implement, quality and efficiency were investigated with questionaire and interview. Results The teachers and students think theOSCE well in different views. Conclusion The OSCE is applicable to the graduation practice skills testing of Rehabilitation Therapeutics.
6.Effect of mobile network platform in out-of-hospital rehabilitation of patients with total knee arthroplasty: a Meta-analysis
Jinghua XIA ; Ou CHEN ; Xiaoyan LV ; Yingjuan CAO
Chinese Journal of Practical Nursing 2020;36(13):1036-1041
Objective:To evaluate the effect of mobile network platform in out-of-hospital rehabilitation of patients with total knee arthroplasty.Methods:CNKI, Wanfang, VIP, Chinese biomedical literature database, PubMed, Cochrane Library, EMbase and Web of Science database were searched by computer. To collect randomized controlled trials of out-of-hospital rehabilitation management for knee arthroplasty patients using mobile network platform. Two researchers independently screened literature, extracted data and evaluated quality according to inclusion exclusion criteria,and Stata 12.0 software was used for meta-analysis of the required documents.Results:A total of 10 articles were included for meta-analysis. A total of 933 patients were included, 471 in the intervention group and 462 in the control group. Meta-analysis showed that the knee function of patients with total knee arthroplasty managed by mobile network platform were better than those of the control group, and the difference was statistically significant(standardized mean difference( SMD) value was 1.25, 95% confidence interval( CI) 0.84-1.66, P<0.01), but the effect on improving range of motion ( SMD value was 0.29, 95% CI -0.30-0.87, P>0.1) and quality of life( SMD value was 0.90, 95% CI -0.25-2.05, P>0.1) was no difference. Conclusions:There is no obvious effect on the range of motion of the knees and quality of life, while to some extent, the application of mobile network platform in out-hospital rehabilitation management of total knee replacement patients can effectively improve the function of knees. It potentially speed up patients′rehabilitation process.
7.Abnormal Brain Structure and Function in First-Episode Childhood- and Adolescence-Onset Schizophrenia: Association with Clinical Symptoms.
Yanhong XIA ; Dan LV ; Yinghui LIANG ; Haisan ZHANG ; Keyang PEI ; Rongrong SHAO ; Yali LI ; Yan ZHANG ; Yuling LI ; Jinghua GUO ; Luxian LV ; Suqin GUO
Neuroscience Bulletin 2019;35(3):522-526
8.Advance in Contents and Standard of Disability-related Data
Longjun HU ; Fengshui CHANG ; Dan LI ; Jinghua WU ; Lianding XUE ; Xiaohong LI ; Chunli YIN ; Jiatong ZOU ; Qiaoyan LIU ; Xiaojing HUANG ; Zhuoying QIU ; Jun lv
Chinese Journal of Rehabilitation Theory and Practice 2018;24(10):1140-1145
This paper reviewed international documents of disability statistics. The results showed that all disability measurements had been adopted International Classification of Functioning, Disability and Health (ICF) terminology and approach. Disability statistics in US tailored to ICF framework and classification. Disability statistics in China had partially adopted ICF approach.
9.Effects of hypoxic preconditioning on energy metabolism of mitochondria in mouse hippocampal HT22 cells
Ruifang Qi ; Na Li ; Lijun Wang ; Jun Lv ; Ruili Shi ; Baohui Ma ; Jinghua Shi ; Xiaoqiong Hao ; Guo Shao
Acta Universitatis Medicinalis Anhui 2022;57(10):1585-1588,1594
Objective :
To investigate the effect of hypoxic preconditioning (HPC) on mitochondrial energy metabolism in mouse hippocampal HT22 cells and its possible mechanism.
Methods :
In this paper, mouse hippocampal nerve cells HT22 were divided into control group, hypoxia group, HPC group, and the levels of adenosine triphosphate (ATP) and reactive oxygen species (ROS) in each group were measured for observing the effect of HPC on cell mitochondrial metabolism. Western blot was used to detect the expression of target of rapamycin ( mTOR), phosphorylated mTOR protein and autophagy substrate P62 protein; cellular immunofluorescence was used to detect phosphorylated mTOR, and LysoTrackerTM probe was used to detect lysosomes.
Results :
Compared with the control group, the ATP level was significantly decreased and the ROS level was increased in the hypoxia group. Exposed to HPC, the ATP level was increased and the ROS level was decreased. Compared with the control group, the expression of phosphorylated mTOR was down⁃regulated and the expression of autophagy substrate P62 was down⁃regulated in the HPC group.
Conclusion
HPC may affect the energy metabolism of HT22 cells through the mTOR/autophagy signaling pathway, thereby exerting a protective effect on the HT22 cells.