1.Effect of Liujunzi soup on allergic cough in remission stage and total inflammation of children
Chinese Journal of Biochemical Pharmaceutics 2017;37(9):91-93
Objective To evaluate the effect of Liujunzi soup on the total course of disease and inflammatory mediators in patients with remission of allergic cough. Methods Eighty six patients with allergic cough were enrolled in our hospital from April 2011 to April 2012. The patients were randomly divided into observation group (n = 43) and control group (n = 43). The control group was given basic western medicine treatment, the observation group in the control group on the basis of another treatment of six gentleman soup. The levels of inflammatory cytokines, pulmonary function and adverse reactions were compared between the two groups in clinical efficacy, hospitalization time, total course of disease, IL-2, TNF-α and IL-6. Results The total effective rate was 90.70% in the observation group was significantly higher than that in the control group (72.09%)( P<0.05). The duration of hospitalization (13.35 ± 3.24) d and the total course of disease (17.68 ± 4.53) d were significantly shorter than those in the control group (16.23 ±3.10) d, (20.35 ± 4.67) d (P<0.05). The levels of inflammatory factors and pulmonary function in the observation group were statistically significant compared with the control group (P<0.05). No adverse reactions occurred in both groups. Conclusion Liujunzi Decoction combined with western medicine can improve the level of inflammatory cytokines and lung function, shorten the length of hospital stay, the total course of disease and high safety, and have good clinical value.
2.Primary abdominal aortic aneurysm-intestinal fistula(a case report and literature review)
Xinsheng LU ; Yixong LI ; Jingdong LI ;
Chinese Journal of General Surgery 1994;0(05):-
Objective To study the diagnosis and treatment of abdominal aortic anurysm-intestinal fistula(AAA-IF). Methods The diagnosis and treatment of one patient with AAA-IF was reported, while a literateres review of AAA-IF was made. Results A 50 years old femal patient abmitted due to upper abdominal pain for two month, and an AAA was found in the explore laparotomy. The patient suddenly occurred severe upper abdominal pain accompanied with shock and massive upper gastrointestinal bleeding 13 days after the operation. The preoperative suspected diagnosis was AAA-IF. An AAA-IF was ound during emergent operation. AAA-IF resection with artifial vessel replacement, resection of the forth portion of duodenal and upper portion of jejunal were performed together. The patient recovered eventurely except high body temperature. After vigovous antibiotics therapy, the patient recovered. Conclusions AAA-IF is a rare disordor, the mortality can be as high as over 30%. The key points of redecing mortality are that the diagnosis and treatment should be in time; postoperative vigorous antibiotics should be given, because the AAA-IF patient tends to occur septic complications due to the communication occurred between the AAA and intestinal tract.
3.Experimental study of autogenous vein graft connector repairing laryngeal nerve defect in dogs
Zhiming WANG ; Jingdong LI ; Xinsheng LU ; Ledu ZHOU ; Li ZHOU ;
Chinese Journal of General Surgery 1997;0(06):-
Objective To investigate the feasibility of autogenous vein graft as a connector to repair recurrent laryngeal nerve(RLN) defect. Methods 20 healthy dogs were randomly devided into 4 groups: group 1(n=6), 2(n=6), 3(n=5) and control group(n=3). Left RLN of dogs in group 1,2,3 were resected for 1,2,3 centimetres respectively and followed by repairment with autogenous vein graft, while RLNS of dogs in control group were resected but not conducted by autogenous vein graft. Six months after operation, the vocal fold movement, phonation and induced action potensial as well as morphologic observation of the aryngeal muslces were studied. Results In group 1, phonation of dogs was all restored to normal. The vocal fold of RLN resected side showed no atrophy symmetrical to the normal side and adducted apparently when phonating. Furthermore thyroarythenoid muscle and posterior cricoarytenoid muscle both could generate induced action potentially. Regenerated nerves in verin graft and distal nerve were observed by light microscope and electron microscope. In group 2,3 and control group hoarseness improved six months after op eration, the vocal fold of RLN resected side was atrophied apparently and fixed paramedianly. Fissure existed in glottis when vocal fold closed, and compensative movement of opposite vocal fold across over the median line was found. Thyoarthenoid muscle and posterior cricoarytenoid muscle unable to generate an action was found. Regenerated nerves were not observed in vein graft or distal nerve by light microscope and electron microscope. Conclusions It is feasible to repair RLN defect in certain length by autogenous vein graft.
4.Study on effects of Rhizoma coptidis decoction on myoelectric activity of uterine smooth muscle of unpregnancy rats and its action mechanism
Yan LU ; Xiaomin QIN ; Jingdong XU ; Dehong LI ;
Chinese Traditional Patent Medicine 1992;0(06):-
Objective:To observe the effects of Rhizoma coptidis decoction on the myoelectric activity of womb of virginal rats and to discuss its mechanism. Methods: The changes of uterine myoelectric activity of rats were recorded by Biolap 98 biological system with a pair of mini bipolar Ag AgCl electrodes implanted on the uterine serosal surface. Rhizoma coptidis decoction was injected to find their effects on uterine myoelectric activity of rats, then M, H 1,?,L calaium channel and prostaglandin synthetase were blocked or inhibited respectively to be observed their influence Rhizoma coptidis decoction. Results:Rhizoma coptidis decoction can significantly increase uterine myoelectric activity of rats. After M and H 1 receptors were blocked, the effects of Rhizoma coptidis decoction were partially decreased. The effects of Rhizoma coptidis decoction were disappeared with L calcium channels blocked. But, nothing happened if ? receptor was blocked or prostaglandin synthetase was inhibited. Conclusions: Rhizoma coptidis decoction can significantly increase uterine myoelectric activity of rats, which may be associated with M receptor, H receptor and L calcium channels, nothing with ? receptor and synthesis or releasing of prostaglandin.
5.Development and application of management software for hospital medical record flow
Li CHEN ; Ying ZOU ; Hongmei LU ; Jingdong XIE
Chinese Medical Equipment Journal 1993;0(06):-
Objective: To develop a bar code method for the medical record management under the voluntarily established software of medical record management and retrieval system.Method: The software of medical record management system and bar code as well as the necessary processing,management and application system were established.Results: With the development of information technology and the bar code technology mature application,the bar code automatic diagnosis technology was applied to the medical record management process including recycling,cataloging,reorganization,arrangement,storage,pigeonhole,the top carriage,the bottom carriage,circulation and return,which could enhance the data acquisition and information processing speed,guarantee the accurate rate in the movement link,raise the hospital management level,and provide detailed,accurate and timely data for the hospital superintendent.Conclusion: The research on the software system of medical record management and the bar code application can enhance the hospital medical record utility and reduce the medical record administrative personnel's working pressure.The software of medical record management system and bar code are practical and effective in medical record management.
6.Overview of Research and Application of Knowledge Expression and Semantic Reasoning of Ontology in the Diabetes Field
Xiaoxian WANG ; Chenxi XIA ; Fangfang ZHANG ; Naiji LU ; Jingdong MA
Journal of Medical Informatics 2017;38(7):56-61,67
Through the retrieval of literatures about the research and application of ontology in the diabetes field in PubMed,IEEE/ IET Electronic Library,ACM,WANFANG,CNKI,VIP and other Chinese and English databases,as well as the search engines Google Scholar and Baidu Scholar,the paper shows the current situations and summarizes the main study contents.The result shows that the study achievements of ontology in the field of diabetes increase rapidly and there are obvious advantages in semantic comprehension in recent decade.
7.Research Status and Implications of Foreign Medical Automatic Question Answering System
Fangfang ZHANG ; Jingdong MA ; Xiaoxian WANG ; Naiji LU ; Chenxi XIA
Journal of Medical Informatics 2017;38(3):2-6,25
The paper analyzes the documents related to the foreign medical automatic Question Answering (QA) system,and compares the differences between automatic QA and traditional network information retrieval,describes the automatic QA system in the aspects of application researches,common tools and relevant technologies.Combining foreign related researches,it also discusses the current key problems of medical automatic QA system and the implications for China in order to offer reference for further research.
8.VM_(26)+DDP regimen given concurrently with whole-brain radiotherapy for brain metastasis from lung cancinoma
Jiaming WANG ; Hailong BIAN ; Changxing LU ; Changlu WANG ; Jingdong GUO
China Oncology 2001;0(03):-
Background and Purpose:In recent years,along with marked rise in the incidence of lung cancer,the incidence of brain metastasis from lung cancer has increased year by year.The main treatment strategy of lung cancer with brain metastasis is irradiation,while so far there are only few researches concerning chemotherapy combined with radiotherapy for these patients.The aim of this study is to evaluate the therapeutic effect,survival rate and toxicity of chemotherapy with VM_(26)+DDP regimen given concurrently with whole-brain radiotherapy in lung cancer with brain metastasis.Methods:From Sep.2000 to Oct.2001,forty-one patients with lung cancer with brain metastasis were divided randomly into two groups: 20 patients(14 male,6 female) received concurrent chemoradiotherapy(chemoradiotherapy group),the other 21 patients(14 male,7 female) received only radiotherapy(radiotherapy group).In the chemoradiotherapy group,the average age was 50 years with range 40 to 70 years,16 patients were non-small-cell lung cancer,4 patients were small-cell lung cancer.In the radiotherapy group,the average age was 52 years with range 40 to 73 years and 19 patients were non-small-cell lung cancer,2 patients were small-cell lung cancer.For both groups,the same radiation technique was given with conventional fraction.Radiotherapy was delivered by 6MV.Fractionations of 3Gy/fraction/day was delivered 10Gy/5 factions/week.The total dose was 30Gy/10Fr/2W.For chemoradiotherapy group,the patients were also given concurrent chemotherapy(VM_(26) 60mg/m~(2)/ day iv on days 1-3,cisplatin 60 mg/m~(2) iv on the 1~(st)day).Results:The response rate and complete response in the chemoradiotherapy group was significantly higher than that in the radiotherapy group(75% ?? 38.10%,P
9.Classification of Diabetes Diet Problems Oriented by Deep Automatic Question Answering
Fangfang ZHANG ; Jingdong MA ; Xiaoxian WANG ; Naiji LU ; Chenxi XIA
Journal of Medical Informatics 2017;38(3):12-16
Taking the diet problem of diabetic patients as an example,the paper puts forward the problems classification system based on functions in the view of users,classifies the problems put forward by patients through the Support Vector Machine (SVM) algorithm,and provides important support for the construction of the deep automatic Question Answering (QA) system.
10.The selection of treatment modalities for primary liver cancer:a report of 265 cases
Zhiming WANG ; Ledu ZHOU ; Xinsheng LU ; Sen YOU ; Jingdong LI
Chinese Journal of General Surgery 2000;0(12):-
Objective To explore the methods and outcome of comprehensive therapeatic for primary liver cancer. Methods Various therapeutic methods and outcome of 265 patients with primary liver cancer admitted in the last five years, were analyzed retrospectively .The group consisted of 238 male, and 27 female patients. The average age 47.5 years. Operation was performed in 215 cases and non-operative treatment is 50 cases. Operative treatment included resection of hepatic cancer and/or adjuvant therapy. Non-operative therapy included transcatheter hepatic chemo-embolization(TACE),percutaneous ethanol injection (PEI)、drug delivery system(DDS)、cryosurgery、radiofrequency ablation(RFA). Results The resection rate, and mortality and morbidity rates were 57%(215/377), 74.9%(161/215), 0.5%(1/215), and 19% respectively. The overall 1-,2-,3-year survival rate were 78.9 %,59.3%,33.5%, respectively, in patients who received comprehensive treatment centered around surgical resection, and 62.3%,32.3%,22.8%, respectively, in 45 patients who received non-surgical resection treatment. Conclusions Liver resection combined with other nonoperative modalities are ideal ways to treat primary liver cancer at the present time, and for different stages of primary liver cancer different treatment modalities are used.