1.Development and application of a machine to weigh and move trauma patients
Tengjiong LI ; Qiuzi ZHANG ; Jingbin CHEN
China Medical Equipment 2016;13(4):6-8
Objective:To design a machine for trauma patients to be weighed and translocation, increase the accuracy of clinical drug using, reducing secondary damage and improve the life quality.Methods: The machine which consists of mechanical system, driving system, weighing system, power supply system, control system. It has the advantages of high efficiency and safety, simple operation, easy translation motion.Results:It resolved the problems in weighing and translocation.Conclusion: The machine reduces the labor intensity of medical staff, and avoids the secondary damage in the transportation process at the same time. With its good effect, the machine obtains very high value in clinical application.
2.Clinical significance of patterns of intrathoracic lymph node metastasis in non-small cell lung cancer:an analysis of 314 patients
Haichen ZHANG ; Jingbin SHI ; Jiandong ZHA
Chinese Journal of Radiation Oncology 2014;23(4):294-296
Objective To investigate the patterns of intrathoracic lymph node metastasis in nonsmall cell lung cancer (NSCLC) and to provide a theoretical basis for the delineation of radiotherapy target volume.Methods A retrospective analysis was performed on the clinical data of 314 NSCLC patients after operation.Our focus was to investigate the distribution characteristics and metastatic extent of intrathoracic lymph nodes and their relationship with tumor size,pathological type,and primary site.Comparisons between groups were made by one-way analysis of variance.Results The frequencies of metastases to lymph nodes at stations 4,5,7,10,and 11 were all above 12%,while those at stations 1,2,3,6,8,and 9 were all below 12%.The lymph node metastasis rate was similar on the primary tumor site (P =0.102).The patients with T3 and T4 NSCLC had a significantly higher frequency of N2 lymph node metastasis than those with T1 and T2 NSCLC (17.0% vs.11.6%,P =0.002) ;the patients with adenocarcinoma had a significantly higher frequency of N2 lymph node metastasis than those with squamous cell carcinoma (34.5 % vs.23.2%,P =0.008).Conclusions For patients with T3 and T4 NSCLC of adenocarcinoma subtype,we should highlight the lymph nodes at stations 4,5,7,10,and 11 when delineating the radiotherapy target volume after operation.
3.The comparative analysis on effects of two methods for blood screening before blood donation
Jingbin ZHENG ; Li ZHANG ; Congxi BI
International Journal of Laboratory Medicine 2016;37(5):611-612,615
Objective To investigate the practical application values of copper sulfate method and hemocyte analyzer in blood do‐nation screening .Methods A total of 1 500 blood samples of donors were randomly collected and determined by using both copper sulfate method and hemocyte analyzer .Taking hemocyte analyzer as the reference method ,the sensitivity and specificity of copper sulfate method for detecting hemoglobin(Hb) were calculated .The overall detection rates of abnormal blood samples determinded by the two methods were calculated ,as well .Statistical comparisons were performed on the test data from both methods .Results A total of 29 donors(accounted for 1 .9% ) with unacceptable Hb value were found by using copper sulfate method .For all blood do‐nors ,the sensitivity and specificity of copper sulfate method for Hb screening before blood donation was 99 .7% and 82 .8% ,respec‐tively .And there were no statistically significant differences in sensitivity and specificity between the two methods for Hb estima‐tion(P>0 .05) .There were 336 donors with abnormal blood samples detected by using hemocyte analyzer .Taking hemocyte analy‐zer as the reference method ,only 8 .6% of donors with abnormal blood samples were screened out by using copper sulfate method . Conclusion The copper sulfate method could be used for Hb screening before blood donation .While because of its limitations ,such as relatively low specificity and inadequate screening items ,the hemocyte analyzer shoud be utilized before blood donation if the con‐ditions permit .
4.Effect of Rosuvastatin on the function of vascular endothelial and inflammatory response in patients with acute myocardial infarction after intervention
Jingbin WANG ; Feng TONG ; Ying ZHANG ; Qin YANG
Clinical Medicine of China 2010;26(8):815-817
Objective To observe the effect of Rosuvastatin on the function of vascular endothelial and inflammatory response in patients with acute myocardial infarction ( AMI) after intervention. Methods Seventy-eight patients with AMI patients underwent coronary angiography and PCI treatment The patients were divided into the control group (38 patients) and the Rosuvastatin group (40 patients) after PCI treatment All patients were routinely used nitrates, low molecular weight heparin,aspirin,clopidogrel,the Rosuvastatin group were treated on the basis of conventional medication plus service Rosuvastatin 10 mg/time, once a day. Both groups were continuous medicated for 6 months. Cardiovascular events of all patients, the serum lipids, inflammation-related biomarkers and indicators of vascular endothelial function were followed up for 6 months after discharge. Results The cardiovascular events in the Rosuvastatin group (5. 0% ) was significantly lower than that of the control group (18.4%) after discharge within 6 months (χ2 = 4. 52, P < 0. 05). After 6 months of discharge, the serum lipids, the serum IL-6, hs-CRP,plasma ET-1 and ox-LDL of Rosuvastatin group ((2. 16 ±0. 54)mmol/L,(4. 16 ±0. 28)mmol/L,(6. 80 ± 2. 65) ng/L, (4. 02 ± 1. 58) mg/L, ( 62. 45 ± 9. 38) ng/L and 381. 65 ± 39. 73, respectively) was significantly lower than those of the control group ((2.47 ±0. 59) mmol/L, (5. 29 ±0. 31 )mmol/L, (9. 39 ±4. 17) ng/L, (5. 76 ± 1. 52)ng/L, (81. 75 ± 10. 23) ng/L and 485. 91 ±42. 68,respectively) (t =2. 423,16. 910,3. 291,4. 952,8. 691 and 11. 173 , respectively , P <0. 01 ). The serum NO of Rosuvastatin group ( ( 62. 17 ± 17. 69 ) μmol/L) was significantly higher than than that of the control group ( (48. 27 ±18. 35 ) μmol/L) (t = 3.406, P < 0.01 ) . The serious adverse events were not observed in the Rosuvastatin group. Conclusions Rosuvastatin reduces inflammatory reaction after PCI in patients with AMI, improves endothelial function, and reduces adverse reactions.
5.STUDY ON THE PROTECTIVE EFFECTS OF POLYPEPTIDE-Fe ON ACUTE HEPATIC INJURY IN MICE
Lixia WANG ; Jingbin LIU ; Guorong ZHANG ; Anjun LIU
Acta Nutrimenta Sinica 1956;0(04):-
Objective: To study the protective effects of polypeptide-Fe on acute hepatic injury induced by CCl4 in mice. Method:Mice model of acute hepatic injury was set up by CCl4 ig (50mg/kg?d ). and fed with polypeptide-Fe 67.5 mg/kg?d, 675 mg/kg?d and 2 025 mg/kg?d for 30 d respectively. The effects on serum ALT, AST, and ALP and liver TG, TC, GSH, MDA, and SOD avtivities were observed. Results: Polypeptide-Fe decreased the activities of ALT, AST, and ALP in serum and the levels of TG, TC, and MDA in liver, and increased the level of GSH in liver. Middle dosage group of polypeptide-Fe was the most effective one. Conclusion:Polypeptide-Fe showed significant antioxidant ability in protecting acute hepatic injury induced by CCl4 in mice.
6.The Contrast Analyses of the Signs of CT and Hepatic Arteriography of theLiver Cancer Combined the Arteriovenous Fistulae
Jingbin WANG ; Caixia LI ; Chunzhi ZHANG ; Fuliang LI
Journal of Practical Radiology 2001;0(05):-
Objective To study the signs and the value of CT enhanced scanning in diagnosing the liver cancer combined arteriovenous fistulae(AVF).Methods 50 cases of the liver cancer combined AVF had plain and enhanced scanning by spiral CT,then proved by hepatic arteriography.The signs of CT and hepatic arteriography were contrast analyzed.Results CT scan showed 17 cases of artery-portal vein fistulae (centre),10 cases of artery-the small branch of portal vein fistulae(periphery),3 cases of artery-liver vein fistulae,5 cases combined the signs aforementioned,2 cases combined the artery-portal vein fistulae and the artery-liver vein fistulae,and the 13 cases no the characteristic signs of CT,37 cases of the signs of AVF were found by CT,sensitivity 74%.26 cases were diagnosed as AVF,postitive rate 52%.Conclusion The development of portal vein and/or the inferior caval vein ahead in artery phase,especially the parenchyma of the lobes,segments and subsegments of liver,may be a foundation of the diagnosis of AVF.And we discussed the limitation of the CT examination in diagnosing this complication.
7.Related factors of ST-segment resolution in patients with acute ST-segment elevation myocardial infarction after revascularization operation
Guoju LYU ; Qijun ZHANG ; Dan LI ; Li YU ; Jingbin WANG
Chinese Journal of Postgraduates of Medicine 2015;(11):823-827
Objective To observe the factors affecting inadequate ST-segment resolution in patients with acute ST-segment elevation myocardial infarction after emergency percutaneous coronary intervention (PCI). Methods The patients with acute ST-segment elevation myocardial infarction undergoing emergency PCI were enrolled for study. According to the ratio of ST-segment resolution, 186 cases were divided into inadequate ST-segment resolution group (54 cases) and relatively adequate ST-segment resolution (132 cases). Clinical data of two groups were compared. The single factor and multiple Logistic regression analysis were performed to determine the factors influencing inadequate ST-segment resolution. Results Pre-infarction angina was protective factor of inadequate ST-segment resolution after emergency PCI (OR=0.361, 95%CI 0.131-0.994, P<0.05). Anterior myocardial infarction, attack-to-balloon time, Killip classification and white blood cell counts were risk factors of inadequate ST-segment resolution (OR=2.389, 95%CI 1.194-4.781;OR=1.655, 95% CI 1.082-2.532; OR=1.319, 95% CI 1.026-1.695; OR=1.184, 95% CI 1.004-1.396, P<0.05). Conclusions Patients with pre-infarction angina could reduce the risk of inadequate ST-segment resolution after PCI. Patients with anterior myocardial infarction,long attack-to-balloon time, Killip classification≥2 and high blood cell counts could increase the risk of inadequate ST-segment resolution, and earlier and more active clinical intervention should be taken.
8.Gait Analysis after Posterior Cruciate Ligament and Posterolateral Corner Reconstruction
Jin ZHANG ; Hua FENG ; Jingbin ZHOU ; Zengyu TAO ; Lei HONG ; Xuesong WANG ; Hui ZHANG
Chinese Journal of Sports Medicine 2010;(3):260-263
Purpose To analyze the gait of patients following reconstruction of posterior cruciate ligament(PCL) and posterolateral corner(PLC).Methods Between March 2007 and April 2008,16 patients with combined PCL and PLC injuries-deficient knee underwent the reconstruction with allograft.Dial test were performed before surgery,and gait analysis and dial test were assessed 1 year after reconstruction.Sixteen healthy volunteers were used as controls.Results There are no differences in the time-distance factors and kinematics between patients and controls(P>0.05).The torque of knee extension revealed significant difference between patients and controls(P<0.01).Mean abtorsion angle of the patients increased 16.5°±6.2° before surgery;whereas the angle increased-4.4°±7.8° 1 year after surgery(P<0.01).The maximal mean abtorsion angnlation from gait analysis was 14.1°±15.7° and from dial test was 29.7°±1 5.2°,respectively.There was a strong linear correlation(r=0.9671,P<0.05)between the outcomes from dial test and gait analysis.Conclusion After reconstruction of the PCL and PLC,the gait of patients became almost normal 1 year after operation,except the torque of knee extension.
9.Application of Medpor in restoration of craniofacial contour deformities
Qiming ZHAO ; Xudong ZHANG ; Xin LU ; Dongsheng XIA ; Dongsheng MAO ; Dongmei HE ; Jingbin GAN ; Chengju ZHANG
Chinese Journal of Medical Aesthetics and Cosmetology 2008;14(4):243-245
Objective To explore the effects of Medpor in surgical treatment of craniofacial de-pressed deformities. Methods Combining with other surgical methods, 37 patients with craniofacial de-pressed deformities were treated with Medpor. Of them, 29 cases of craniofacial depression and defects subjected to trauma, 6 cases were progressive facial hemiatrophy and 2 case were angle of mandible de-formity. All were followed up from three months to four year. Results Facial configurations and func-tions of all the 37 cases were greatly improved after the treatment, without any complication of infection or rejection;patients were all very satisfactory or relatively satisfied with the results. Conclusion Med-por is an ideal implant material to correct the deformity of earaniofacial, and combining with others methods, the treatment of earaniofacial deformity can obtain good results.
10.Simultaneous Determination of the Content of Ethinylestradiol and Norelgestromin in Hormonal Patches by RP-HPLC
Linjie ZHANG ; Jingbin LIU ; Qi ZHANG ; Lin WANG ; Yongliang ZHAO ; Yinzhi XIE
China Pharmacy 2015;(24):3429-3430,3431
OBJECTIVE:To establish a method for simultaneous determination of ethinylestradiol and norelgestromin in hor-monal patches. METHODS:RP-HPLC method was performed on column of WondaCract ODS-2 with mobile phase of metha-nol-0.5% phosphoric acid(68∶32,V/V)at a flow rate of 1.0 ml/min,the detection wavelength was 220 nm,the detection tempera-ture was 25 ℃,and sample volume was 20 μl. RESULTS:The linear relationship was 0.872-130.8 μg/ml for ethinylestradiol(r=0.999 6) and 0.880-132.0 μg/ml for norelgestromin (r=0.999 7);RSDs of precision,reproducibility and stability tests were no more than 1.03%,average recoveries were resectively 101.50%(RSD=0.99%,n=9) and 101.68%(RSD=0.95%,n=9). CON-CLUSIONS:The established method is simple and accurate,and can be used for the content determination of ethinylestradiol and norelgestromin in hormonal patches.