Objective To explore the clinical efficacy of continuous intravenous pump of Shengmai injection for treatment of patients with acute coronary syndrome(ACS)combined with cardiogenic shock. Methods In the period from January 2005 to March 2011,33 hospitalized patients with ACS complicated by cardiogenic shock were selected in the treatment group,and in the same period,32 in-patients with ACS were enrolled in the control group, According to traditional Chinese medicine(TCM)syndrome type,the treatment group was subdivided into Yin xutype(Yin deficiency,15 cases),Qi xu type(Qi deficiency,11 cases),Xue yu type(blood stasis,7 cases). Conventional western medicine treatment was given to the two groups,besides,Shengmai injection in 30-60 mL intravenous drip,once a day was applied in the control group,while in the treatment group,Shengmai injection in 10-100 mL/h trace pump continuous intravenous infusion was given,after the blood pressure returned to normal,the infusion was changed to 5 mL/h trace pump continuous intravenous injection for consecutive 5-7 days. After treatment, the changes of clinical efficacy,blood pressure,heart rate ,improvement of clinical symptoms were observed in two groups,and the changes of mean arterial pressure(MAP)in cases with different syndromes in treatment group were also investigated. Results The rates of the significant therapeutic effect and total effect in the treatment group were obviously higher than those in the control group〔significant effect:69.7%(23 cases)vs. 46.9%(15 cases);the total efficacy:90.9%(30 cases)vs. 62.5%(20 cases),both P<0.05〕. The comparisons of blood pressure and heart rate before and after treatment in the two groups were not significant(all P>0.05). After 48 hours of treatment in the two groups,the clinical symptoms were all improved〔chest pain:2 cases(6.1%)vs. 10 cases(31.3%),sweating:3 cases(9.1%)vs. 13 cases(40.6%),shortness of breath:4 cases(12.1%)vs. 12 cases(37.5%),all P<0.05;heart palpitations:5 cases(15.2%)vs. 9 cases(28.1%),nausea:3 cases(9.1%)vs. 4 cases(12.5%),both P>0.05〕. In treatment group,the increase of MAP in patients withYin xutype(mm Hg,1 mm Hg=0.133 kPa)was higher than that in patients with Qi xu type and Xue xu type(105.00±8.53 vs. 91.00±9.53,89.00±3.53,both P<0.05). Conclusion Continuous intravenous injection of Shengmai injection has significant therapeutic effect for treatment of patients with ACS combined with cardiogenic shock.

Objective To observe the distribution rules of syndrome factors and common syndromes of patients with idiopathic fatigue(IF).Methods 268 cases with IF were collected in outpatient,and the distribution and combination of syndrome factors were analyzed.Results Altogether eight syndrome fac-tors were found,and the frequency from high to low was listed as qi stagnation,qi deficiency,fire heat, yin deficiency,blood deficiency,yang deficiency,phlegm and blood stasis.The top three combination syndromes were syndrome of qi depression transforming into fire with qi deficiency (n =162),syndrome of qi stagnation with qi deficiency (n =84)and syndrome of qi-yin deficiency with qi depression transfor-ming into fire (n =83).The rest combination types were listed as syndrome of qi depression transforming into fire with qi deficiency-caused phlegm,syndrome of phlegm-heat stasis with qi deficiency,syndrome of phlegm stasis and qi stagnation of qi transforming into fire ,syndrome of qi stagnation with qi /yang deficiency,syndrome of qi depression transforming into fire with qi deficiency and blood stasis.Conclu-sion In patients with IF,qi stagnation,qi deficiency and fire were the common syndrome factors,and the common syndromes were syndrome of qi depression transforming into fire heat with qi deficiency and syndrome of qi stagnation with qi deficiency.