1.Progress of study on the KAI1 gene in gynecological tumor
Cancer Research and Clinic 2010;22(z1):64-66
KAI1 is a recently identified metastasis suppressor gene located at human chromosome 11 p11.2. KAI1 protein is a member of the structurally distinct family of cell surface glycoprotein and belongs to transmembrane 4 protein superfamily. KAI1 expression is down-regulated in many metastatic tumor cells. Down-regulation of KAI1 expression also plays an important role in the genesis and development of gynecological tumor.
2.Therapeutic Effect of Trimetazidine on Patients with Alcohol Cardiomyopathy
Chinese Journal of Primary Medicine and Pharmacy 2010;17(17):2322-2323
Objective To observe the therapeutic effect of Trimetazidine on patients with alcohol cardiomyopathy based on conventional medicine. Methods 46 cases with alcoholic cardiomyopathy were randomly divided into congroup (22 cases) and observation group(24 cases), they were given conventional therapy and additional Trimetazidine for 4 weeks respectively, we estimated therapeutic effect based on 6 min walking experiments, left entricular ejection fraction, and the content of C-reactive protein. Results The results of 6 min walking experiments (543.5 ±69.3) vs (492.7 ± 72.7),left ventricular ejection fraction (44.3 ± 8.6) vs (49.8 ± 9.5) and C-reactive protein content (5.2 ± 0.7) vs (8.9 ± 1.1) in observation group were better than control group. Conclusion Additional Trimetazidine could improve cardiac function by improving cardiacenergy metabolism and anti-inflammatory effect on alcohol cardiomyopathy patients ,Trimetazidine was of great value to generalization.
3.Analysis on maintenance data in No.1 Military Hospital Information System
Chinese Medical Equipment Journal 2003;0(10):-
By analyzing the covariance of maintenance data in Hospital Information System,this paper points out the wrong operations of Hospital Information System and puts forward a series of valid solutions including software improvement,timely communication with users,reinforcement of operator training.
4.Rehabilitation Training on Family Caregiver of Schizophrenic in Rural Areas
Chinese Journal of Rehabilitation Theory and Practice 2010;16(12):1192-1194
ObjectiveTo observe the effect of rehabilitation training on family caregiver of schizophrenic in rural areas.Methods60 schizophrenic patients in rural area were divided into rehabilitation group and control group. The rehabilitation group and their caregivers received training of family rehabilitation for 12 months. The caregivers in the control group only received interview. Brief Psychiatric Rating Scale (BPRS) and Social Disability Screening Schedule(SDSS) were used to assess the patients before, 6 months and 12 months after training. The self-made caregiver questionnaire was to assess mental knowledge and family harmony of the caregivers.ResultsPsychiatric knowledge and family harmony for caregivers significantly changed in the rehabilitation group after the family rehabilitation training. There were significant differences in the BPRS and SDSS score between the rehabilitation group and the control group.ConclusionThe family rehabilitation training can benefit the rural schizophrenic patients and their caregivers.
5.Gradual Community-based Rehabilitation for Schizophrenia in Changping Countryside: A Comparative Study
Chinese Journal of Rehabilitation Theory and Practice 2009;15(9):885-886
Objective To explore the effect of gradual community-based rehabilitation on schizophrenia in the countryside. Methods 60 rural patients with schizophrenias were randomly sampled and divided into two groups: the rehabilitation group and the control group. The patients in the rehabilitation group were intervened with comprehensive rehabilitation by specialist, while those in the control group were intervened with follow-up survey. They were assessed with the Brief Psychiatric Rating Scale (BPRS), Scale for Assessment of Negative Symptoms (SANS) and Social Disability Screening Schedule (SDSS) before and 3, 6, 9, 12, 15, 20 months after the rehabilitation. Results The differences in scores of BPRS, SDSS and SANS were more significant with the time of rehabilitation. Conclusion The outcome of the community-based rehabilitation for schizophrenias may associate with the persistence in the countryside.
6.Clinical applications of blood biomarkers in ischemic stroke
Chinese Journal of Laboratory Medicine 2014;37(7):497-500
Early diagnosis and timely treatment are two critical factors in reducing the cerebral damage and improving prognosis for ischemic stroke patients.The only proved effective way is to intravenously administer recombinant tissue plasminogen activator for thrombolytic therapy.However,the narrow time window restricts its application.One rapid and effective blood test,or auxiliary examinations such as computer tomography which may aid early diagnosis of ischemic stroke would contribute to treatment and intervention promptly,then take a pivotal role for the disease prognosis.Herein,the reported proteins and RNA markers are summarized and analysed in clinical application of acute ischemic stroke likewise.
7.The effect of breast-feeding on newborns' pain caused by heel prick
Chinese Journal of Nursing 2010;45(5):429-431
Objective To evaluate the effect of breast-feeding on newborns' pain caused by heel prick. Methods A convenient sample of sixty newborns from a hospital in Beijing undergoing heel prick for the Newborn Screening Program Blood Test were enrolled. They were randomly divided into breast-feeding group and control group. The newborns in the breast-feeding group began to receive breast-feeding at two minutes before the heel prick until 8 minutes after the heel prick finished. The newborns' grimace,cry,heart rate (HR) and oxygen saturation (SaO_2) were recorded and compared between the two groups. Results There were significant differences on the starting time and lasting time of grimace and cry caused by pain,numbers of crying neonates,SaO_2 during and 1 to 4 minutes after heel stick,as well as the recovery time of SaO_2 after heel stick between the two groups (P<0.05 or P<0.01). Conclusion Breast-feeding can relieve newborns' pain caused by heel prick.
8.Pregnancy outcome in women with lupus nephritis
Chinese Journal of Primary Medicine and Pharmacy 2009;16(4):623-624
Objective To study the outcome of pregnancy with lupus nephritis. Methods The clinical data of 9 pregnancies with lupus nephritis were retrospectively malyzed. Results Hypertension,proteinuria,injured renal function and abnormal serological marker were complicated with nine patients with lupus nephritis in pregnancy. The outcome of pregnancy was as following:abortion 2 cases,stillbirth 1 case,premature delivery 4 cases,term delivery 2 cases. All neonate survived without malformation. There was no postpartum hemorrhage or death. Patients with active SLE had very high fetal mortality( 100% ). And SLE got worsen in 50% of them. However,fetal mortality rate in pa-tients with controlled or quiescent SLE was 11.1% ,which was much lower than it in other patients(P<0.05). Con-clusion Lupus nephritis should be controlled before pregnancy. Pregnancy outcome could be improved by careful multidisciplinary monitoring and proper usage of adrenal cortical hormone.
9.A Structural Equation Modeling of Perceived Academic Self-efficacy, Learning Stress, and Learning Burnout of High School Students
Chinese Journal of Clinical Psychology 2006;0(05):-
Objective: To build a relationship model of perceived academic self-efficacy, learning stress, and learning burnout of high school students. Methods: 674 high school students were surveyed with Learning Stress Scale of High School Students, The Perceived Academic Self -efficacy Scale, Scale of Learning Burnout of High School Students. Results: Learning stress had a direct effect on a low level of learning efficacy, perceived alienation to teacher and physical exhaustion (The direct effect value were -0.22,0.12,0.27). At the same time, perceived basic ability and perceived control partially mediated the impact of learning stress on the low level of learning efficacy, perceived alienation to teacher and physical exhaustion (the mediated effect value were -0.155 and-0.264, 0.066 and 0.299, 0.089 and 0.233). Perceived basic ability and perceived control fully mediated the relationship between learning stress and emotional exhaustion (the mediated effect value were 0.033 and 0.387). Conclusion: The students with a higher level of stress reported suffering more learning burnout than those with a lower level of stress, and vice versa.
10.Drug Consultation Records in Our Hospital:Retrospective Analysis of 1663 Cases
China Pharmacy 2007;0(35):-
OBJECTIVE:To improve the quality of drug consultation.METHODS:The drug consultation records of a total of 1 663 cases in our hospital from July 2004 to July 2007 were analyzed statistically by a retrospective method.RESULTS:Of the drug consultation records of a total of 1 663 cases,the chief questions consulted were adverse drug reactions and long-term medication safety(25.2%),dosage and administration(21.1%),medication for special populations(9.7%),drug interactions(8.1%),pharmacological action and indications(7.1%),and generic name and composition of drugs(5.2%).CONCLUSION:The drug consultation service in our hospital achieved a remarkable efficacy in guiding physicians and pharmacists on rational drug use;however,it has its problems and remains to be improved further.