Objective To observe the effect of intravenous administration of dexamethasone on airway complications after laparoscopic cholecystectomy (LC). Methods 66 patients who were treated with laparoscopic cholecystectomy in Wenling hospital of traditional Chinese medicine were divided into the control group and the observation group, 33 cases in each group. The control group were injected with saline 2 mL and the observation group were received dexamethasone 10mg by intravenous infusion. The incidence of complications and complications were observed in the two groups at different times after treatment. Results At 1 hours, 4 hours, 12 hours and 24 hours after extubation, the differencesof the incidence of sore throat and throat pain degree between the two groups was not statistically significant. Conclusion Dexamethasone intravenous administration has no obvious effect on reducing airway complications after laparoscopic cholecystectomy.

Objective To study and analyze the effect of small dose dexamethasone on the prevention of throat pain at perioperative period of thyroid tumor resection. Methods 112 cases with thyroid cancer treated by resection in Wenling hospital of traditional Chinese medicine from July 2014 to July 2016 were selected as the study subjects which were divided into the study and the control group. The control group were given saline by intravenous injection, The study group were given small dose of dexamethasone intravenous injection. The preventive effect of postoperative throat pain and postoperative blood glucose level were compared between the two groups. Results Statistical analysis showed that the postoperative VAS score in the study group was better than that in the control group. The blood glucose level in the study group was better than that in the control group, the difference was statistically significant (P<0.05). Conclusion Perioperative treatment with small doses of dexamethasone is excellent for patients with thyroid tumors treated with resection. It can help patients prevent postoperative sore throat and has excellent application value and is worthy of clinical promotion.

Objective T_O analyze the electrophysiological features of shoulder-hand syndrome(SHS)fol- lowing stroke and investigate the relationships between peripheral nerve damage and the factors causing SHS.Meth- ods Fifty-eight stroke patients were divided into an SHS group(39 patients with shoulder-hand syndrome)and a model group(19 patients without shoulder-hand syndrome).Standard sensory and motor nerve conduction studies were performed with 58 of the patients,including sensory nerve conduction velocity(SCV),amplitude of the sensory nerve action potential(SNAP),distal motor latency(DMI)and the amplitude of the compound muscle action poten- tial(CMAP)of the median nerve.A needle electromyogram(EMG)test was performed on the abductor pollicis of the affected side with both groups.Results The needle EMG showed abnormal insertion potential,fibrillation po- tential and positive sharp waves in all 39 cases of the SHS group,which was significantly higher than in the model group.The amplitude of the sensory nerve action potential(7.77?4.34 mV)and the amplitude of the compound muscle action potential(10.13?3.15 mV)were significantly lower than those of the model group.Abnormal ampli- tude was more severe in sensory nerves than in motor nerves.Conclusion Peripheral nerve damage was found in the shoulder-hand syndrome patients,and this damage was mainly the dystrophy of axonal neuropathy.The damage severity was more in sensory nerves than in motor nerves.The study could offer an useful clue of prevention and treat- ment of shoulder-hand syndrome.

Adult ; Arrhythmogenic Right Ventricular Dysplasia ; physiopathology ; Electrocardiography ; Humans ; Male ; Middle Aged

Objective To assess the diagnostic value of chronotropic index in identifying coronary artery disease (CAD). Methods One hundred and sixty two patients with suspected CAD were referred for a routine treadmill exercise electrocardiogram and subsequently underwent selective coronary angiography within 3 weeks. The magnitude of ST segment depression and chronotropic index were measured by a computerized ECG system. CAD was defined by coronary angiography. Results In detecting CAD, the sensitivity was 70. 1% versus 60.9% (P< 0.05) ,the specificity was 84.0% versus 73.3% (P<0.05), and the accuracy was 76.5% versus 66.7% (P< 0.05) by chronotropic index and standard electrocardiographic test criteria. The value of Kappa statistic for chrono-tropic index consistency in our experiment was 0.534(>0.4). The number of diseased vessels was correlated with the mean value of chronotropic index. The chronotropic index decreased from 0.88±0.09 in patients without coro-nary disease to 0.68±0.06 in those with 3 vessels involved (P<0.01). A more closed relationship was found be-tween chronotropic index and lesion in the fight coronary artery. Conclusions Chronotropic index is possibly a valu-able positive index for the diagnosis of CAD. The sensitivity,specificity and accuracy of chronotropic index are signif-icandy higher than those of standard electrocardiographic test criteria in identifying CAD.

Objective To investigate the neurosurgery nurses turnover intention and the psychological contract status to analyze the relationship between them. Methods The Departure Will Scale and Questionnaire of Psychological Contract were used to survey 128 neurosurgery nurses from seven general hospitals in Lishui city. Results Of neurosurgery nurses turnover intention scale was (2.24±0.71) points, whose leaving intend was stronger;Psychological contract items was (4.17±0.67) points, which organization responsibility score wasbelow employees responsibility; Hierarchical regression analysis showed that the psychological contract in the organization responsibility (organization specification responsibility, organization, personal responsibility and organizational development responsibility) could predict neurosurgery nurses′ willingness to leave, which could be able to explain their willingness to leave 13.5%of the variation. Conclusions Neurosurgery nurses′willingness to leave is strong, and psychological contract is an important factors affecting the will of their departure.

Objective To investigate the effect of UCP2 on cell proliferation, apoptosis, metastasis in cervical squamous carcinoma. Methods Plasmid?mediated downregulation of UCP2 was obtained in cervical cancer cell lines. MTT, flow cytometry and transwell chamber assay were conducted to detect the ability of proliferation, apoptosis and metastasis. Characteristics of UCP2 protein was analyzed by bioinformatics methods. Results (1)UCP2 was verified to be downregulated by qRT?PCR and Western blotting assay.(2)MTT, apoptosis assay and transwell chamber assay showed that the proliferation of SiHa cell was significantly inhibited, and the apoptosis rate was significantly increased, and metastasis was markedly deduced (P < 0.05). (3) Bioinformatic analysis showed that UCP2 was located in mitochondria with several phosphorylation sites, and UCP2 interacted with other proteins to produce biological effects. Conclusion UCP2 may play an important role in the occurrence and development of cervical cancer, and it is expected to be a new target for the early diagnosis and treatment of cervical cancer.

Objective To evaluate the quality of life (QOL) in adults with epilepsy.Methods The QOLIE-31 and the SDS were administered to 33 adults with epilepsy who met the entry criteria, and 17 healthy volunteers who had the similar personal characters. Results Patients' scores of SDS were adversely associated with seven of the eight QOL domains (except for medication effect) independent of other factors. Duration of the disease was the independent risk factor to overall health and medication effect. The GTC group (17 subjects) and the CPS group (16 subjects) were both obviously compared with the control group in medication effect (GTC group 61.0?23.8,CPS group 56.6?19.4,control 100.0?0.0) and seizure worry domains ( P

Objective To develop real-time quantitative PCR method for measuring the amount of fetal DNA in maternal plasma and the changing patterns of fetal and maternal DNA with the pregnant progress. Methods Fifty-eight women were recruited at 7～42 weeks of gestation with singleton pregnancy determined by ultrasound scan. QIAGEN DNA kits was used to extract fetal DNA from maternal plasma. Fluorescent quantitative PCR(FQ-PCR) were applied to determine the concentration of ?-actin and SRY gene in extracted DNA. Results Thirty-seven male fetus were all identified among the 58 pregnant women (100%) and no Y signal was detected in the other 21 pregnancies with female foetus. The median level of fetal DNA in those pregnancies with male foetus was 9.08 copies/ml (3.5～12.8) in early pregnancy,45.41 copies/ml (14.38～76.5) in mid-pregnancy and 300.95 copies/ml (84～840) in late pregnancy. Conclusions The concentration of fetal DNA increases with the progress of pregnancy. Maternal plasma may be valuable in noninvasive prenatal diagnosis.

Objective To assess the intensity of the pain and its negative impact on patients with protrusion of lumbar intervertebral disc (PLID) through using a case-control study. Methods 94 patients with PLID and 398 control individuals were enrolled in this study. The pains were assessed using McGill questionnaire. Results The sensory pain score(5.22?2.22), affective pain score (2.68?0.81)and VAS score (7.79?1.42)in the patient group were significantly higher than those in the control group (P