Objective To study the immune state and correlated strategy of patients with hepatic cirrhosis and primary hepatic carcinoma.Methods 17 patients with hepatic cirrhosis and 8 patients with primary hepatic carcinoma(PHC) in our hospital were collected since 2002.The indexcs of immune function were detected in all patients and some were re-examined.Results It was found that although the immune index varied in patients suffering from severe liver diseases,some regularities were shown as follows:(1)CD4 and CD4/CD8 in T lymphocyte subset declined markedly(P

Objective: To summarize our experience on perioperative anesthesia management of patients with crush syndrome caused by earthquake under field condition. Methods: The clinical anesthesia data of 10 patients with crush syndrome caused by China Wenchuan earthquake, who were treated under field condition, were retrospectively analyzed, and our experience on perioperative anesthesia management was summarized. Results: After volume therapy, urine alkalization, and stabilization of internal environment, the 10 patients underwent debridement, decompression by fasciotomy or amputation under epidural anesthesia or brachial plexus block plus psychological therapy and moderate tranquillizer. During the operation, the patients showed smooth respiratory and cardiovascular characteristics without pain. Conclusion: Under field condition, regional anesthesia can provide adequate analgesic effect during and after the surgery. Early fluid resuscitation and life support are vital to the safety and life of patients.

OBJECTIVE To investigate the distribution and drug resistance of nosocomial infection pathogens. METHODS Statistical methods were used to analyz the data of pathogens origin and drug resistance from 2005 to 2007. RESULTS A total of 326 strains were isolated from 604 nosocomial infection cases (54.0%),from which the Gram-negative bacilli were predominate (44.1%). The isolation rate ot fungi and Gram-positie bacteria was 41.6% and 14.3%,respectiviely. The top three pathogens were the fungi (41.6%),Pseudomonas aeruginosa14.3%,and enterobacter (10.6%). The rate of ampicillin-resistant Escherichia coli was 100%.The isolation rate of MRSA and MRCNS was up to 100.0% and 80.0%. CONCLUSIONS Fungi is common high among pathogens.The emergence of drug-resistant pathogens will continue to be a serious problem,we must take it intimately.

Objective:To explore the effect between Xuezhikang and rosuvastatin on carotid intima-media thickness (IMT) .Methods :A total of 90 patients with carotid atherosclerosis were randomly and equally divided into control group ,Xuezhikang group and rosuvastatin group according to number table .After six-month treatment ,changes of blood lipid levels and IMT were compared among three groups .Results:Compared with before treatment ,there were significant improvements in blood lipid levels (except high density lipoprotein cholesterol ) and IMT after six months in Xuezhikang group and rosuvastatin group , P<0.05~ <0.01 ;compared with control group after treat-ment ,there were significant reductions in levels of triglyceride [ (2.12 ± 0.97) mmol/L vs .(1.17 ± 0.47) mmol/L , (1.87 ± 0.97) mmol/L] ,total cholesterol [ (5.95 ± 0.65) mmol/L vs . (5.14 ± 0.71) mmol/L ,(4.75 ± 0.64) mmol/L] and low density lipoprotein cholesterol [LDL-C , (3.64 ± 0.45 ) mmol/L vs . (3.01 ± 0.51 ) mmol/L , (2.15 ± 0.55) mmol/L] ,IMT [ (1.15 ± 0.15) mm vs .(1.01 ± 0.08) mm , (0.98 ± 0.02) mm] and total plaque score [ (6.10 ± 2.12) scores vs .(4.61 ± 2.08) scores , (4.59 ± 2.34) scores] in Xuezhikang group and rosuvastatin group , P<0.05~ <0.01 .After treatment ,there were no significant difference in above indexes between Xuezhi-kang group and rosuvastatin group ( P> 0.05 all) except that LDL-C level of rosuvastatin group was significantly lower than that of Xuezhikang group ( P< 0.05 ) .Conclusion:Both Xuezhikang and rosuvastatin can significantly improve carotid atherosclerosis ,and their therapeutic effects are equal .

Firstly, this paper analyzed the significance of strengthening medical students’ ecological moral ed-ucation under the view of Beautiful China. Secondly, it discussed the present situation of ecological moral and the reasons of lacking of ecological moral in medical students. At last, the authors pointed out the countermeasures to strengthen the moral cultivation of medical students’ ecological countermeasures under the view of Beautiful China. Therefore, we must strengthen the top-level design to ensure the ecological moral education enter into the national education system, enhance to maintain power to build the full-area coverage ecological moral teaching system, and strengthen institutional construction to establish long-term mechanism of ecologic moral education.

Microcirculation is closely related to occurrence and development of disease, so it is of significance in noninvasive imaging of microcirculatory structure and function in vivo.Photoacoustic imaging is one of the main techniques in microcirculation imaging, which has the characteristics of high contrast, high detection depth and high sensitivity to tissue function.A review of the literature showed that photoacoustic technique can noninvasively image and quantitatively measure microcirculatory structure, vasoconstriction and vasodilation, concentration of hemoglobin, oxygen saturation, blood velocity and direction, oxygen metabolism level in a certain depth of living tissue in real time.Research progress in photoacoustic imaging of microcirculation in subcutis, cerebral cortex, tumor, eye and other tissues is reviewed in this paper.

The incidence rate of hepatocellular carcinoma (HCC) is increasing around the world and tends to decrease in East Asia and several regions in China;however, China still has higher incidence rate and mortality rate of HCC than most countries.Studies have shown that long-term antiviral therapy can inhibit HBV replication to a very low level or help patients with HCV infection achieve sustained virologic response, which can further reduce the incidence rate of virus-related HCC.New evidence suggests that compared with nucleos(t)ide analogues, PEG-IFNα has a better effect of secondary prevention.Studies also indicate that interferons play an important role in tertiary prevention of virus-related HCC.This article reviews the epidemiological studies on virus-related HCC in recent years and the role of antiviral therapy in second and tertiary prevention and points out that adequate and effective antiviral therapy is the basis for preventing the development and recurrence of HCC.

Objective: To evaluate the clinical effect of individualized enteral nutritional (EN) support in severe stroke patients.Methods: Totally 120 severe stroke patients with nutritional risk were divided into two groups according to single or double admission number.The 60 patients in the intervention group received an individualized EN with different formula and concentrations according to the clinical status,and supplemented trace elements as occasion required.In the routine group, the patients received EN with standard formula.The energy supply was 83-125 kJ· kg-1·d-1 in both groups.Blood albumin(Alb), pre-albumin(PA), hemoglobin(Hb) and vitamin C(VC) were examined before and after the 21-day nutritional support.The lung infection and gastrointestinal (GI) complications were observed, and the hospital stay and cost were recorded as well.Results: After 21 day''s nutrition support, the serum levels of Alb, PA and VC in the intervention group were not statisticly significant than before (P＞0.05), and the serum levels of Alb, PA and VC were significantly higher than those in the routine group(P＜0.05).The incidence of complications in the in the intervention group was lower than that in the routine group (P＜0.05), and the length of hospital stay and hospitalization was shorter than that in the routine group (P＜0.05).Conclusion: Individualized enteral nutritional support can significantly improve nutritional status, reduce inflammation reactions and GI complications in severe stroke patients, which is worthy of clinical use.

Acupuncture Therapy ; Adult ; Female ; Humans ; Psoriasis ; therapy

Alzheimer's disease (AD) is the most common form of dementia, which affects more than 35 million people worldwide with increasing tendency. AD brings stupendous economic burden for both the society and family. It has become a major global public health issue. Electro-acupuncture (EA) therapy has been widely used in AD treatment with satisfactory results. Based on the basic research, this paper explored the therapeutic effect of EA in AD treatment from the learning ability and morphological changes in AD animal models. From the cholinergic neuronal apoptosis theory, inflammatory response theory, oxidative stress theory and other aspects, the action mechanism of EA in the treatment of AD animal models were reviewed. At last, limitations of EA in AD treatment were analyzed. It proposed the outlook of a new type of EA-music EA in AD treatment. It provided a new idea and method for AD clinical treatment.