1.Application of PBL Method in the Clinical Teaching of Orthopedic Surgery
Jing TIAN ; Bo YU ; Jinxue YUAN
Chinese Journal of Medical Education Research 2006;0(11):-
Debates over PBL have never stopped since its introduction to medical education in 1969 and are even becoming more heated.This paper expounds on the origin and definition of PBL,and then describes and analyzes the application of the clinical teaching in orthopedic surgery.
2.Clinical analysis of the CD_(117)-weak and CD_(117)-negative gastrointestinal stromal tumors:a report of 13 cases
Yuan-Ming JING ; Jing-Qi TIAN ; Xi-Bo LIU ;
Cancer Research and Clinic 2000;0(06):-
Objective To explore the CT features in CD_(117)-weak and CD_(117)-negative gastrointestinal stromal tumors(GIST).Methods The CD_(117)-weak and CD_(117)-negative Gist proved by pathologically and sur- gically in 13 cases were retrospectively analyzed.Results The tumor was located in the stomach in 6 cases, small intestine in 4 cases,colorectum in 2 cases,greater omentum in one case.The most common clinical manifestations were abdominal pain or discomfort in 6 cases,hematemesis or melena in 3 cases.Malignant tu- mors occurred in 8 cases.Benign tumors occurred in 5 cases.A soft tissue was identified in all 13 cases in CT examination.The CT examinations revealed cystic regions and bleeding in 5 cases.Calcification was not noted within the masses in all cases.The mean diameter of benign tumors was 3.4 cm?2.8 cm while that of malig- nant tumor was 7.5 cm?6.2 cm.All the cases underwent operation,the resection rate was 100%.After follow up from 6 months to 4 years in 10 cases,1 case died of tumor recurrence and metastasis,the others survived. Conclusion CD_(117)-weak and CD_(117)-negative Gist occurred more common in the stomach.CT is useful in lo- cation and differentiation of CD_(117)-weak and CD_(117)-negative gastric stromal tumors with regard to benign or malignant.Surgery is the main method for final diagnosis and treatment.
3.Short-term curative effect observation on treatment of tumor by Shengling liquid combined with intervene therapy.
Jing-bo YUAN ; Zhao-xun LIU ; Chong LIU
Chinese Journal of Integrated Traditional and Western Medicine 2005;25(3):263-264
Antineoplastic Combined Chemotherapy Protocols
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therapeutic use
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Cisplatin
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administration & dosage
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Cyclophosphamide
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administration & dosage
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Drug Therapy, Combination
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Drugs, Chinese Herbal
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therapeutic use
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Female
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Fluorouracil
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administration & dosage
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Humans
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Injections, Intra-Arterial
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Lung Neoplasms
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drug therapy
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Male
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Middle Aged
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Mitomycin
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administration & dosage
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Phytotherapy
5.Pituitary carcinoma: report of a case.
Jing ZHOU ; Nan-yun LI ; Zhi-qiang ZHANG ; Chi-yuan MA ; Bo YU ; Hang-bo ZHOU
Chinese Journal of Pathology 2013;42(2):123-125
Adenoma
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pathology
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Brain Neoplasms
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secondary
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Chromogranin A
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metabolism
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Diagnosis, Differential
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Follow-Up Studies
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Humans
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Magnetic Resonance Imaging
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Male
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Middle Aged
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Neoplasm Recurrence, Local
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Pituitary Neoplasms
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diagnosis
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metabolism
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pathology
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surgery
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Reoperation
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Synaptophysin
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metabolism
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Temporal Lobe
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pathology
6.Primary squamous cell carcinoma of breast: report of 2 cases.
Jing-ping YUAN ; Xiu-xue YUAN ; Yue-hong YANG ; Yan ZENG ; Bo LUO
Chinese Journal of Pathology 2010;39(7):488-489
Adult
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Breast Neoplasms
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metabolism
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pathology
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surgery
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Carcinoma, Squamous Cell
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metabolism
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pathology
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surgery
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Female
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Humans
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Keratin-5
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metabolism
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Lymph Node Excision
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Lymphatic Metastasis
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Mastectomy, Radical
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methods
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Middle Aged
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Transcription Factors
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metabolism
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Tumor Suppressor Proteins
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metabolism
7.Software and hardware design for the temperature control system of quantitative polymerase chain reaction.
Xian-bo QIU ; Jing-qi YUAN ; Qi LI
Chinese Journal of Medical Instrumentation 2005;29(4):252-254
A temperature control system for quantitive polymerase chain reaction (PCR) is presented in the paper with both software and hardware configuration. The performance of the control system has been improved by optimizing the software and hardware design according to the system's properties. The control system has been proven to have a good repeatability and reliability as well as high control precision.
Equipment Design
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Microcomputers
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Polymerase Chain Reaction
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instrumentation
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Software
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Software Design
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Temperature
8.The association between C-reactive protein-757T/C gene polymorphism and carotid artery artherosclerosis in patients with ischemic cerebrovascular disease
Haicheng YUAN ; Bo XU ; Jing CHEN ; Ling WANG ; Junfang LI ; Dong WANG ; Congzhen LI
Chinese Journal of Neurology 2013;(4):224-228
Objective To explore the relationship of a polymorphism c.757T > C in C-reactive protein gene (CRP) and carotid artery atherosclerosis in patients with ischemic cerebrovascular disease (ICVD).Methods A case-control study investigated 276 ICVD patients and 125 controls matched for age and sex.Genotypes of-757T/C in CRP were analyzed in patients with ICVD using polymerase chain reaction-restriction fragment length polymorphism.The level of serum C-reactive protein was detected by using immune scatter turbidimetry and the intima-media thickness of common carotid artery and internal carotid artery were measured by color Doppler ultrasonography.The relationship between the polymorphism -757T/C in CRP and carotid atherosclerosis was assessed.Results The genotypes of the polymorphism -757T/Cin CRP in the ICVD group (207/276(75.0%),65/276(23.6%),4/276(1.4%)) was significantly different from the control group (75/125 (60.0%),46/125 (36.8%),4/125 (3.2%) ; x2 =9.531,P =0.008),the frequence of T allele in patients with ICVD (479/552(86.8%)) was increased significantly compared to the control group (196/250 (78.4%)),the frequence of C allele in the ICVD group (73/552(13.2%)) was decreased significantly in contrast to the control group (54/250 (21.6%) ;x2 =9.056,P =0.004).Among the patients with ICVD,the level of serum C-reactive protein in patients with-757TC/CC genotype was elevated significantly than that with-757TC/CC ((4.2± 1.6) mg/L vs (2.7 ± 1.9) mg/L; t =5.900,P < 0.01).Logistic regression analysis demonstrated that the-757C allele in CRP was related to the carotid artery atherosclerosis (OR =1.379,95% CI 0.852-0.864,P =0.023).Conclusions The polymorphism-757T/C in CRP maybe related to the risk of developing ICVD.The frequency of the-757C allele can increase the level of serum C-reactive protein.And this polymorphism may be associated with carotid artery atheroselerosis in patients with ICVD.
9.Application effect of contact team in international cooperation of Chinese registered nurse-helping smokers quit project (CRN-HSQ)
Yuan YU ; Cheng CHEN ; Tinghui CHEN ; Yi YANG ; Jing XU ; Xin HE ; Yang ZHAO ; Bo XU
Chinese Journal of Practical Nursing 2013;(5):73-75
Objective To complete the large international cooperation nursing research project Adapting a Smoking Cessation Intervention Distance Learning Program to Educate Nurses in China(CRN-HSQ) cooperating with International Society of Nurses in Cancer Care (ISNCC).Methods The contact team was formed,convenience sampling method was used to choose 350 clinical nurses in our hospital.They were trained and investigated by web-based education mode.Results The contact team finished the project tasks smoothly.The satisfaction degree of research object with the contact team was high.Conclusions Establishment of contact team is good for shortening the information flow path,reducing the information transmission error,increasing the research objects' confidence and reducing the research objects turnover.It is very helpful for project with long period and large number of research objects.
10.Primary and metastatic hepatic neuroendocrine carcinoma: a clinicopathological study
Wenshu ZHANG ; Jing ZHAO ; Yuan JI ; Bo YANG ; Lingli CHEN ; Yunshan TAN ; Akesu SUJIE ; Xiongzeng ZHU
Chinese Journal of Hepatobiliary Surgery 2012;18(3):161-165
Objective To study the clinicopathological features of primary and metastatic hepatic neuroendocrine carcinoma.Methods The records of 35 patients with primary hepatic neuroendocrine carcinoma and 35 patients with metastatic hepatic neuroendocrine carcinoma were retrospectively reviewed.These patients served as the primary group(priNET,n=35)and the metastasis group (metNET,n=35),respectively.Results There were significant differences between the two groups of patients in gender,site,size and number of tumor(P<0.05).Although there was no significant difference between the two groups in the distribution of the tumors in the two lobes of liver (P>0.05),priNET had more tumors localized to one lobe of liver while metNET had more tumors involving both lobes of liver(P<0.05).Conclusions Gender,size,site and number of tumor may play an important role in the differentiation of primary or metastatic hepatic neuroendocrine tumor.