1.The kinds of oral rehydration salts solution and its application in treating acute diarrhea of children
International Journal of Pediatrics 2010;37(1):62-64
Since the oral rehydration salts solution(ORS) has been used to treat acute diarrhea of children, there are different kinds of ORS in order to satisfy the need of clinical work. They are the initial WHO-ORS, other substances-supplemented ORS and the reduced osmolarity ORS, each of which has their own efficiency and advantage.
2.Effect of operation time on the treatment of children with congenital internal strabismus
Fang MEI ; Jing QIAN ; Juan CHEN ; Zhijun CHEN
Journal of Chinese Physician 2016;18(3):355-357,361
Objective To investigate the surgery opportunity choice of congenital esotropia.Methods A retrospective research was taken using the clinical data and the results of the treatment of 146 inpatients with congenital esotropia in our department from Mar 2012 to Mar 2015.The correction rate,lackingcorrection rate,and over-correction rate were compared between early surgery group and late surgery group on time of 1 week after surgery and 6 months after surgery,respectively.Results In all the 146 patients,88 (60.3%) had an esotropia deviation greater than or equal to 40 pupil distance (PD),38 (26.0%) combined with amblyopia,12 (8.2%) combined with nystagmus,30 (20.5%) combined with inferior oblique muscle overaction,6 (4.1%) combined with dissociated vertical divergence (DVD).There was no significant difference between early surgery group and late surgery group on correction rate,lacking-correction rate,and over-correction rate on the time of 1 week after surgery and 6 months after surgery,respectively.Conclusions Congenital strabismus should take surgery at the early-stage,especially for those have large angles.It is better to be operated before 2-year old for a better formation and recovery of binocular visual function.
3.The values of Rockall, Blatchford and AIMS65 scoring systems in the diagnosis and treatment of patients with acute upper gastrointestinal bleeding
Huiling LIU ; Yan LUO ; Changping LI ; Mei MEI ; Jing CHEN ; Fang SU ; Yan ZHANG ; Yanli CHEN
Tianjin Medical Journal 2017;45(4):423-427
prognosis of patients with acute upper gastrointestinal bleeding (AUGIB). Methods A total of 130 patients with AUGIB in our hospital were enrolled in this study from August 2014 to August 2016 . Three kinds of scoring systems including Rockall, Blatchford and AIMS65 were used to evaluate the risk classification of the patients. Patients were followed up for 2 months. The incidence rates of re-bleeding and death within 2 months after admission were observed. Data of prognosis in patients with AUGIB were compared between the three scoring systems in the prognosis of patients with AUGIB, including the risk classification and the prediction accuracy of re-bleeding and death. Results There were no significant differences in the re-bleeding rate and fatality rate between the groups divided by Rockall and Blatchford scoring systems ( P>0.05). According to the grouping results of AIMS65 scoring system, the re-bleeding rate of low-risk group was lower than that in high risk group (1.45%vs. 13.11%, P=0.01), but there was no significant difference in fatality rate between the two groups (P>0.05). The values of area under the curve (AUC) of predicting re-bleeding rates by using Rockall, Blatchford and AIMS65 scoring systems were 0.6258, 0.6910, and 0.7241, and the values of AUC of predicting fatality rates were 0.7031, 0.7969, and 0.7031 by using receiver operating characteristic curve (ROC) analysis. There were no significant differences between them (P>0.05). The values of AUC of predicting re-bleeding rates by using the risk grading calculation by Rockall, Blatchford and AIMS65 scoring systems were 0.6189, 0.6139 and 0.7254 (P>0.05). But the values of AUC of predicting fatality rates were 0.6211, 0.6641 and 0.7695 (P<0.01). Conclusion The operation method of AIMS65 scoring system is simple and convenient, which is applicable to a wide range of patients with AUGIB. In the prediction of re-bleeding and mortality, AIMS65 scoring system has high accuracy and stability, which is worthy of promoting in clinical application.
4.Effect of Peitu Shengjin Recipe on Nutritional States and Immune Functions of Stable Phase COPD Patients.
Jing GONG ; Ning CHEN ; Xiao-mei HAO ; Hui LI
Chinese Journal of Integrated Traditional and Western Medicine 2015;35(5):534-536
OBJECTIVETo explore the effect of Peitu Shengjin Recipe (PSR) on nutritional states and immune functions of stable phase chronic obstructive pulmonary disease (COPD) patients.
METHODSTotally 62 stable phase COPD patients were randomly assigned to the treatment group (30 cases) and the control group (32 cases). All patients inhaled Seretide (50/500 µg), twice per day. Besides, patients in the treatment group additionally received PSR, one dose per day. After three months of treatment, the COPD assessment test (CAT) score, the index of nutritional states [including body mass index (BMI) , thickness of skin fold (TSF), mid-arm muscle circumference (MAMC), serum albumin, serum prealbumin], and immune functions (including IgA, IgM, and IgG) were compared between the two groups.
RESULTSBy the end of the treatment, the CAT score decreased more obviously in the treatment group than in the control group (P < 0.05). The improvement of BMI, TSF, MAMC, serum albumin, and serum prealbumin was better in the treatment group than in the control group (P < 0.05). IgM and IgG also increased more in the treatment group (P < 0.05). There was no statistical difference in IgA between the two groups (P > 0.05).
CONCLUSIONSAdditionally use of PSR could improve nutritional states and immune functions of stable phase COPD patients to some extent. Meanwhile, it also could improve their health related quality of life.
Body Mass Index ; Drugs, Chinese Herbal ; therapeutic use ; Humans ; Nutritional Status ; Pulmonary Disease, Chronic Obstructive ; drug therapy ; immunology ; Quality of Life ; Serum Albumin
6.Promote multidisciplinary study on anthracycline-induced cardiotoxicity in children.
Shu-bao CHEN ; Mei-rong HUANG ; Jing-yan TANG
Chinese Journal of Pediatrics 2013;51(8):565-568
Anthracyclines
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administration & dosage
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adverse effects
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Antineoplastic Agents
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administration & dosage
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adverse effects
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Biomarkers
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blood
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Cardiomyopathies
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chemically induced
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diagnosis
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prevention & control
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Cardiotonic Agents
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therapeutic use
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Child
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Child, Preschool
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Echocardiography
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Heart
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drug effects
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Heart Diseases
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chemically induced
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diagnosis
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prevention & control
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Humans
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Risk Factors
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Survival Analysis
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Troponin I
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analysis
7.Treatment of orbital wall fracture in the anophthalmic patient.
Zhi-yuan CHEN ; Jing-ming LIU ; Dong-mei LI
Chinese Journal of Stomatology 2008;43(11):693-694
Adult
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Eye Injuries
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surgery
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Female
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Humans
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Orbital Fractures
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surgery
8.A comparative analysis of EEG and cognitive function in children with benign epilepsy associated with central temporal spikes
Jing ZHANG ; Fang CHEN ; Mei JIN ; Yakun DU ; Suzhen SUN
International Journal of Pediatrics 2016;43(4):329-332
Objective To study the EEG discharge index, intelligence test and event-related potential P300 in BECT, and to analyze the change of EEG discharge index and cognitive function before and after the treatment.Methods Sixty patients with BECT were enrolled in this study, they were treated with EEG, intelligence tests and P300 before and after the treatment.Results (1) The EEG discharge index were reduced remarkly after treatment in BECT with levetiracetam and lamotrigine, the difference was statistically significant (P < 0.05).(2) Comparing before and after 3 or 6 months treatment, the latency of P300 had reduced with significant difference (P < 0.05).(3) After 3 months treatment, VIQ and FIQ has no obvious improvement, but PIQ has improved.After 6 months treatment, VIQ、 PIQ and FIQ were improved.The difference was statistically significant (P < 0.05).(4) There was a negative correlation of EEG P300 latency (r =0.175), as well as there was a negative correlation between EEG discharge index and intelligence test (r =0.044).Conclusion There is impaired cognitive function in BECT, especially the more frequently the EEG discharge, the more extended of P300 latency, as well as the more serious damage of intelligence and cognition after treatment.The intelligence were improved after treatment with Levetiracetam and lamotrigine, the longer the treatment time, the more obvious of intelligence levels improve.
9.Application of self-made pelvic bag in treatment for patients with unstable pelvic fracture
Mei LIU ; Chunjing YANG ; Jiahu FANG ; Xi CHEN ; Jing YANG
Modern Clinical Nursing 2017;16(1):63-65
Objective To explore the effect of the self-made pelvic bag on patients with unstable pelvic fracture.Methods Toally 24 patients with unstable pelvic fracture from January 2013 to June 2014 were set as control group and used conventional nursing.Toally 30 patients from July 2014 to December 2015 were set as observation group.The self-made pelvic bag was used in the observation group for pelvic fixation and suspension traction.The degree of pain was compared between the pre-and post-use of the bag.Result The pains after using pelvic bag in the observation group were significantly lower than that of the control group (P<0.001).Conclusions The self-made pelvic bag can be effective for the pelvic fixation and suspension for the patients with pelvic traction.At the same time it can relieve the pain.
10.HPLC analysis of the constituents of Radix Puerariae absorbed into blood
Mei ZHANG ; Feng QIU ; Xuejun XIE ; Jing LIU ; Xiao CHEN
China Journal of Traditional Chinese Medicine and Pharmacy 2005;0(03):-
Objective: To sieve the bioactive constituents of Radix Puerariae,serum pharmacochemistry research was performed.Method: Based on the establishment of HPLC fingerprints of Radix Puerariae,the constituents absorbed into blood were determined by comparing the HPLC fingerprints of the methanol extracts,tested serum samples and blank serum sample.Results: Four compounds absorbed into blood were detected,among which two were original constituents of Radix Puerariae(including puerarin),the other might be metabolites of the original constituents.Conclusion: These four constituents absorbed into blood were possible bioactive components of Radix Puerariae.Further studies on them will help clarify the bioactive constituents and mechanisms of Radix Puerariae.