1.Document Analysis of89Cases Adverse Reaction Caused by Levofloxacin
China Pharmacy 2001;0(07):-
OBJECTIVE:To discuss the general regularity and the characteristics of the adverse reaction resulted from Levofloxacin so as to provide references for the rational use of drugs in the clinic.METHODS:89cases of adverse reaction resulted from Levofloxacin covered by the medical and pharmaceutical periodical of recent10years were statistically classified and analyzed.RESULTS:The adverse reaction were mainly manifested as allergic reactions and symptoms in neural system,digestive system and respiratory system,and the adverse reaction were more likely to occur in the senile patients.CONCLU-SION:Great attention should be paid to the anti-bacteria effect of Levofloxacin and the danger posed by its adverse reaction in the clinic.
3.The relevance of anti-lymphocyte antibody with primary Sj(o)gren syndrome
Rulin JIA ; Jing LI ; Jing HE ; Chun LI ; Zhanguo LI
Chinese Journal of Rheumatology 2014;18(4):232-235,后插1
Objective To investigate the relationship between anti-lymphocyte antibody (ALA) and clinical and immunological parameters in primary Sj(o)gren syndrome (pSS).The significance of ALA and lymphopenia in pSS was explored.Methods Serum samples were obtained from 143 patients with pSS.Clinical and laboratory data were collected.Sera from 45 healthy individuals were collected as the controls.Serum ALA IgG was detected by indirect immunofluorescence test (IIFT).x2 test and t test were used for statistical analysis.The reasons of lymphopenia in pSS patients were analyzed.The correlation between ALA,lymphopenia and clinical manifestations as well as laboratory parameters was analyzed.Results ① Of the 143 pSS patients,25.2%(36/143) were serological positive for ALA,which was significantly higher than the normal group (6.5%,5/77) (x2=27.496,P<O.01).② The prevalence of leukopenia (55.6%,20/36),lymphopenia (77.8%,28/36),anti-nuclear antibody(80.5%,29/36) and C3 decrease(50.0%,18/36) was higher in pSS patients with ALA than those without (x2=8.296,25.348,3.929,3.866,P<0.05).③ 46.2%(66/143) patients had lymphopenia.Comparing with patients with normal lymphocyte count,the incidence of ALA positive,leukopenia,PLT decrease and anti-SSB antibodies positivity was significantly higher in patients with lymphopenia (x2=27.496,51.344,5.320,8.950,7.782; P<0.05).Conclusion The ALA is likely to be a meaningful sera marker for pSS patients with lymphopenia,and this suggests that it has an important role in the clinical progress of SS.
5.Advances in Sertoli-Leydig cell tumour of the ovary.
Jing-li SHI ; Li-na GUO ; Jing-he LANG
Chinese Journal of Pathology 2008;37(9):631-633
Female
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Genes, p53
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immunology
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Humans
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Ovarian Neoplasms
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genetics
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pathology
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Ovary
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pathology
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Proto-Oncogene Proteins
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immunology
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metabolism
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Proto-Oncogene Proteins p21(ras)
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Proto-Oncogenes
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immunology
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Sertoli-Leydig Cell Tumor
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genetics
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pathology
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ras Proteins
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immunology
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metabolism
6.Significance of antibody against ?-fodrin-derived polypeptide in diagnosis of Sjgren′s syndrome
Jing HE ; Jing LI ; Zhanguo LI ; Qiaolin CHEN ;
Chinese Journal of Rheumatology 2003;0(10):-
Objective To investigate the sensitivity and specificity of anti ? fodrin polypeptide antibody in Sjgren′s syndrome (SS) patients.Methods Synthesized ? fodrin polypeptide was used as substrate in enzyme linked immunosorbent assay (ELISA) to detect the specific antibody in sera of SS and other rheumatic diseases.Results Antibody against ? fodrin polypeptide were detected in 73% of patients with primary SS,40% of patients with secondary SS,19 5% of patients with SLE,29 5% of patients with RA,and 3 8% of normal blood donors.The positive rates of ? fodrin polypeptide antibody in primary and secondary SS (73% and 40%,respectively) were significantly higer than those in SLE,RA and normal controls ( P
8.Case of craniocerebral trauma-induced optic nerve injury.
Ling-Xin LI ; Lin YIN ; Jing HE
Chinese Acupuncture & Moxibustion 2014;34(5):454-454
9.Summary of the national symposium on prevention of misdiagnosis and mistreatment in otorhinolaryngology head and neck surgery.
Ying-yuan HE ; Xin JIN ; Jing LI
Chinese Journal of Otorhinolaryngology Head and Neck Surgery 2010;45(2):97-99
Congresses as Topic
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Diagnostic Errors
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Head
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surgery
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Humans
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Neck
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surgery
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Otolaryngology