Objective　To study the effects of Fuyuansan(Chinese herbal medicine) on microcirculation of steroid-induced necrosis of femoral head.Methods　40 male adult New Zealand rabbits were randomly divided into three groups:model group(n=15),Fuyuansan group(n=15) and control group(n=10).Hydroprednisone acetate was injected into the rabbits of the model group using intragluteal injection to produce necrosis models of bone cells of femoral head.The rabbits of Fuyuansan group were injected the same agent using the same methods as model group.Meanwhile,the animals of Fuyuansan group were given Fuyuansan daily.The whole-blood viscosity,triglyceride,serum total cholesterol and intraosseous pressure of each group were determined every two weeks.Results　The whole-blood viscosity,triglyceride,serum total cholesterol and intraosseous pressure of model group remarkably increased,but those of Fuyuansan group increased lightly(P<0.01).Conclusion　Fuyuansan can improve microcirculation of femoral head,change ischemia conditions and prevent the development of necrosis of femoral head.