Electric fields have special biological effects for its heating and non-heating effects. Heating effects are about the technology of radio frequency and microwave thermotherapy while non-heating effects are alternating electric field and pulsed electric field. These electric fields have significant effects for tumor treating.

Objective:This research is to observe the immunity state of lung cancer by radiotherapy in sync with chemotherapy combined with pingxiao capsule,and to evaluate the effect on the immune function and the existence qualitative of pingxiao capsule in lung cancer.Method:Sixty lung cancer patients were parted into two groups at random,one is simple radiotherapy in sync with chemotherapy,the other is radiotherapy in sync with chemotherapy combined with pingxiao capsule.All the two groups were carried out T-cell subgroup experiment at the beginning and three weeks after the therapy.Results:After therapy CD3,CD4 and CD4/CD8 all indicates significant lower level(P

Girdin protein is a kind of actin binding protein,which has the complex molecular structure and takes part in a variety of signaling pathways related with causing cancer.The biological characteristics of Gir-din protein have close association with the proliferation and invasion of malignant tumor.Recent studies have shown that Girdin protein is closely related with occurrence and progress of breast cancer.Girdin protein expres-sion in breast cancer cells can not only promote the progress of breast cancer,but also affect the lymph node me-tastasis and prognosis.Therefore Girdin protein is expected as an independent biomarker to provide a new direc-tion for breast cancer treatment.

Brain Diseases ; etiology ; Brain Neoplasms ; surgery ; Glioma ; surgery ; Humans ; Infection ; etiology ; Postoperative Complications ; etiology ; Recurrence ; Risk Factors

Objective To understand the comprehensive quality status of community nurses in Chongqing and seek the development strategy of community nursing education. Methods Related infor-marion was collected through questionnaire investigation in 104 community nurses from 9 community health service center and 18 community health station. Results The mastering degree of various community nursing knowledge was different among nurses with different education background and different profession-al titles (P ＜ 0.05).More than 80% nurses considered it necessary to cultivate comprehensive technique of special courses ,the ability to cope with community emergencies and self-development in their work.78.9% nurses thought they should reinforce the ability in predicting potential problems in community and solving problems by theirselves, Conclusions We need to strengthen the work belief of community nurses,perfect training conditions,optimize course contents and cultivate nurses' comprehensive ability purposely.

BACKGROUND:Previous studies have found that the expression level of miR-486 in glioma stem cels (CD133+) is significantly down-regulated compared with that in glioma non-stem cels (CD133-), but the effect of down-regulation of miR-486 on CD133+ cels remains unclear . OBJECTIVE: To explore the effect of miR-486 on CD133+ cels. METHODS:CD133+ glioma stem cels and CD133- glioma cels were separated from U87 cels by flow cytometer. miR-486 overexpression glioma stem cels were constructed by lipofection transfection. RESULTS AND CONCLUSION:After sorting and purification, the content of the CD133+ fraction was enriched up to 83.5%. The expression level of miR-468 in CD133+ glioma stem cels was obviously down-regulated compared with that in CD133- glioma cels. CD133+ glioma stem cels overexpressing miR-486 were fabricated successfuly. Results from in vitro experiments showed that miR-486 overexpression could dramaticaly decrease the proliferation of glioma stem cels, induce a cel cycle arrest in G1/S phase for CD133+ glioma stem cels and promote cel apoptosis. These findings suggest that miR-486 can be a suppressor of glioma stem cels, which offers a novel potential therapeutic target for glioma stem cels and human glioma.

With the increment of the workload,high stability is required by hospital information system.When the amount of client exceeds the limit,we must reconstruct the Oracle server in order to meet the needs of workload increment.This article describes the principle of shared server and the reconstructed method from dedicated server to multithreaded server.

OBJECTIVE:To investigate the stability of reduced glutathione sodium after mixing with glucose injection (5% or 10%),glucose and sodium chloride injection or 0.9% sodium chloride injection. METHODS:After mixing of reduced glutathione sodium with glucose injection (5% and 10%),glucose and sodium chloride injection,and 0.9% sodium chloride injection,respectively,the 4 mixtures at 0,0.5,1.0,1.5,2.5,3 h after mixing which were stored respectively in 25℃ or 37℃ thermostatic bath were observed in respect of the changes in appearance,pH values,absorbability,contents and the insoluble particles. RESULTS:After mixing of reduced glutathione sodium with glucose injection (5% and 10%),glucose and sodium chloride injection,and 0.9% sodium chloride injection,respectively,the appearance and pH values of the 4 mixtures showed no obvious change,but the contents and the insoluble particles of the 4 mixtures experienced changes of different degree. CONCLUSION:Reduced glutathione sodium is stable in glucose injection (5% or 10%),glucose and sodium chloride injection or 0.9% sodium chloride injection within 2h after mixing.

Objective To observe the effect of transperineal injection of botulin A toxin on patients with detrusor-external sphincter dyssynergia caused by spinal cord injury. Methods Transperineal injection of botulin A toxin were performed in 6 patients with spinal cord injury (3 with cervical spinal cord injury and 3 with thoraco-lumbar spinal cord injury) complicated by detrusor-external sphincter dyssynergia.55 U of botulin A toxin was injected twice separately. The interval between 2 injections was 3 days.Before treatment, the residual volume of urine after voiding was determined and the maximum urethral pressure was measured by urodynamic testing.One month after treatment the examination mentioned above was repeated. Results The decrease in residual volume of urine was (133.3?70.9)ml.The decrease in maximum urethral pressure was (35.4?25.8)cmH 2O(both P

Objective To observe the evaluation of multi‐tumor marker protein chip in breast cancer with neoadjuvant chemo‐therapy ,and to find high saitivity tumor makers ,then evaluate the clinical significance .Methods Forty health examination persons (control group) and sixty‐four breast cancer patients(experimental group) were accepted with multi‐tumor marker protein chip in‐spection ,then we evaluated the markers of diagnosis .The experimental group patients were accepted four cycles preoperative chem‐otherapy with TAC plan ,and tested multi‐tumor marker protein chip three weeks after therapy .Then we evaluated the clinical sig‐nificance of the markers above‐mentioned .Results The positive rate of CA153 ,CA125 ,CEA and FT was 32% ,27% ,21% and 19% in the experimental group ,it indicated significant change compared with the control group (P<0 .05) .And it indicated signifi‐cant reducing change of CA153 ,CA125 and CEA in the experimental group (P<0 .05) after therapy .The sensitivity would be in‐creased when the four markers were tested combined .Conclusion CA153 ,CA125 ,CEA and FT could be used as assistance diagno‐sis index ;CA153 ,CA125and CEA could keep consistence to the curative effect of neoadjuvant chemotherapy and have clinical value .