Electric fields have special biological effects for its heating and non-heating effects. Heating effects are about the technology of radio frequency and microwave thermotherapy while non-heating effects are alternating electric field and pulsed electric field. These electric fields have significant effects for tumor treating.

Girdin protein is a kind of actin binding protein,which has the complex molecular structure and takes part in a variety of signaling pathways related with causing cancer.The biological characteristics of Gir-din protein have close association with the proliferation and invasion of malignant tumor.Recent studies have shown that Girdin protein is closely related with occurrence and progress of breast cancer.Girdin protein expres-sion in breast cancer cells can not only promote the progress of breast cancer,but also affect the lymph node me-tastasis and prognosis.Therefore Girdin protein is expected as an independent biomarker to provide a new direc-tion for breast cancer treatment.

Objective:This research is to observe the immunity state of lung cancer by radiotherapy in sync with chemotherapy combined with pingxiao capsule,and to evaluate the effect on the immune function and the existence qualitative of pingxiao capsule in lung cancer.Method:Sixty lung cancer patients were parted into two groups at random,one is simple radiotherapy in sync with chemotherapy,the other is radiotherapy in sync with chemotherapy combined with pingxiao capsule.All the two groups were carried out T-cell subgroup experiment at the beginning and three weeks after the therapy.Results:After therapy CD3,CD4 and CD4/CD8 all indicates significant lower level(P

Objective To explore the relationship between age-related cerebral white matter changes (ARWMC) and cognitive function, observe the features of cognitive impairment in ARWMC patients, and provide evidences for preventing and treating cognitive impairment in elderly people.Methods Fifty patients with ARWMC were divided into mild-to-moderate group (n= 26, ARWMC score 1-10) and severe group (n= 24, ARWMC score＞ 10) based on the ARWMC scale of CT/MRI scans. Twenty healthy elderly people, who underwent physical examination in hospital, were selected as control group. The cognitive function was evaluated using Montreal Cognitive Assessment (MoCA,Beijing version). Cognitive functions were compared between patients with ARWMC at different extents and the controls. The correlation between severity of ARWMC and cognitive function, the characteristics of cognitive impairment in patients with ARWMC were analyzed. Results The cognitive function in patients with ARWMC was impaired significantly (the MoCA scores were 26.60±1.23 in control group, 23. 19±2. 62 in mild-to-moderate group and 19.83±3. 09 in sever group, F =39. 930, P = 0. 000). The severity of ARWMC was negatively related with MoCA score (r =-0. 476, P=0. 000). The patients showed cognitive impairment especially in the visuoconstructional and executive functions (F= 13. 189, P＜0.05), delayed recall (F=32.340, P＜0.05) and orientation (F= 15.813, P＜0. 05). Conclusions ARWMC is related with cognitive impairment.The severity of white matter changes is correlated with worse cognitive function.

The all-in-one femtosecond laser corneal refractive surgery,especially small incision lenticule extraction (SMILE),has gained more and more attention in clinic,because of its small incision,“no flap” and corneal biomechanical stability advantages.However,like any other kind of corneal refractive surgery,the all-in-one femtosecond laser refractive surgery not only exists its clinical advantages,but also has its limitations.It is very important to put into perspective clinical advantages and limitations of all-in-one femtosecond laser corneal refractive surgery.

Objective To observe the effects of Conductive Education (CE) on the comprehensive ability of children with cerebral palsy. Methods 100 cerebral palsy children within 3～8 years old were divided into two groups: control group with routine rehabilitation therapy, observing group were applied CE in addition. They were assessed with Gross Motor Function Assessment Scale (GMFM), activities of daily living (ADL) and practical skills for children with cerebral palsy assessment record sheet before and after treatment.Results The scores of GMFM, ADL and practical skills improved after treatment in both groups (P<0.01), but those in the observing group improved more than in the control group (P<0.01). Conclusion CE can improve the motor, self care, communication, sociality, cognize and learning ability in children with cerebral palsy.

ObjectiveTo observe the effect of compound Aescin gel on the massage of the commonly encountered diseases in orthopedic traumatology.MethodsAll 219 patients (acute sprain of waist, radiohumeial epicondylitis, frozen shoulder) were divided into the treatment group (n=112) and control group (n=107). The treatment group was treated with compound Aescin gel in massage treatment, and the control group treated only with massage.ResultsThe recovery rate of the treatment group was higher than that of the control group (P<0.05).ConclusionCompound Aescin gel used in massage can improve effect of commonly encountered diseases in orthopedic traumatology.

Objective To observe the effect of early intervention with conductive education (CE) on high risk infants with cerebral injuries.Methods 98 high risk infants within 3～12 months were divided into control group (n=50) and observation group (n=48). Both groupsreceived routine rehabilitation intervention, and the observation group received CE in addition. The children's mental development cooperationdiagnosis scale (0～6 years old) which edited by Capital Institute of Pediatrics and Institute of Psychology, Chinese Academy of Scienceswas used to test the development quotient (DQ) before and 6 months after treatment. Results The DQ improved more in the observationgroup than in the control group (P<0.001) after 6 months of CE intervention. Conclusion CE can promote the development of high risk infantsin sports, cognitive, speech and social adaptation effectively.

With the body senescing,the endocrine function decreased.In the recent more than ten years,a relationship between pituitary-thyroid axis dysfunction and senile psychosis has attracted increasing attention.Thyroxin is thought to be closely related with the cognitive dysfunction and senile dementia.

Brain Diseases ; etiology ; Brain Neoplasms ; surgery ; Glioma ; surgery ; Humans ; Infection ; etiology ; Postoperative Complications ; etiology ; Recurrence ; Risk Factors