Totrain the evidence-based medicine thought style ofmedical students duringpro-bation teaching,we can enormously elevate the clinical teaching effect and prehension ability of medi-cal students.

Objective To observe the effect nourishing yin, clearing away heat and detoxicating therapy on post-operational patients of uterine cervix cancer. Methods 160 post-operational patients of uterine cervix cancer were randomly recruited into a control group and a treatment group, with 80 cases in each group. The control group was treated with conventional anti-infective and nutrition-supportive therapy. The treatment group received TCM therapy of nourishing yin, clearing heat and detoxicating. Observe complications and prognosis in both groups. Results In the treatment group, there were 21 patients bearing with complications (26.25%), but no case with tumor metastasis and relapse. While in the control group, there were 43 cases bearing with complications (53.8%), 3 cases relapsed but no tumor metastasis. The differences between the two groups were statistically significant (P=0.0064, P<0.01) .Conclusion The therapy of nourishing yin, clearing heat and detoxicating can effectively prevent postoperative complications and improve quality of life.

Objective To investigate the nursing of elderly patients with atrial fibrillation treated by atrioventrieular junction ablation combined with permanent pacemaker implantation. Methods The nurs-ing care process in 60 elderly patients with atrial fibrillation treated by atrioventricular junction ablation combined with permanent pacemaker implantation was reviewed and analyzed. Results All 60 patients had successful outcomes without any complication. Conclusions Preoperative psychological nursing and preparation, rigorous observation and nursing during and post operation guarantee a successful operation.

Objective To establish mice modle of allergic rhinitis(AR) and to study the role of Staphylococcal enterotoxin B(SEB) and ovalbumin(OVA) in the modle.Methods Forty Balb/c mice were evenly randomized into OVA group,SEB group,OVA+SEB group and normal sodium group and AR modle was established.The symptom scores,total serum IgE concentration,IL-4 concentration were analyzed by factorial design.Meanwhile,the morphology change of nasal mucosa was observed.Results The symptom scores in OVA group,SEB group,OVA+SEB group and normal sodium group were 6.80?1.03,0.90?0.99,0.70?0.82,0.60?0.70 respectirely.The interaction of OVA and SEB had statistical significance(P

With an increasing prevalence all over the world,diabetes mellitus is considered as a potential cause of liver cancer in patients with non-viral hepatitis.Whether diabetes mellitus is the cause of liver cancer and related pathogenesis remain unknown.The article reviews recent large-sample cohort studies and confirms that diabetes mellitus increases the incidence rate of liver cancer and affects its prognosis.This article also investigates the association of hepatitis C,obesity,and nonalcoholic fatty liver disease with diabetes mellitus and liver cancer and finds that insulin resistance and activation of chronic inflammatory factors may be involved in the generation and proliferation of cancer cells.This article elaborates on the influence of anti-insulin resistance drugs on the development and progression of liver cancer and points out that diabetes mellitus may be the cause of liver cancer.Effective control of insulin resistance can help to reduce the development and progression of diabetes-associated liver cancer.

Objective To study the value of multi-slice spiral CT (MSCT)urography in diagnosis of urinary obstructive disease.Methods 48 cases with urinary system obstructive disease confirmed by operotion underwent MSCT scan,including plain and multi-phase contrast-enhanced scans.The images of CTA and CT urography were obtanined by the different three dimensional reconstruction.Results Of 48 cases,there were renal and uretal congenital malformation in 15 cases,uretal negative stone in 4,urinary inflammation in 5 ,renal,uretal and bladder tuberculosis in 6,hydronephrosis and hydroureterosis caused by exterior compression in 8 and neoplasm of urinary system in 10.Conclusion Multi-slice spiral CT urography is of significant applied value in diagnosis of urinary obstructive diseases.

OBJECTIVE To establish mice model of allergic rhinitis(AR) and study the role of Staphylococcal enterotoxin B(SEB)and ovalbumin(OVA)in the model,and investigate the change of regulatory T cell(Treg)in the nasal mucosa of mice.METHODS Forty Balb/c mice were randomized into OVA group(A),SEB group(B),OVA+SEB group(C)and normal solution group(D).AR model was established.The symptom scores and count of Foxp3 positive cells in nasal mucosa were analyzed by factorial design.RESULTS The symptom scores in Group A,B,C,D were 0.90?0.99,0.70?0.82,6.80?1.03,0.60?0.70 respectively.Group C was successfully established as AR model.OVA and SEB had interaction(P

Objective To compare the clinical efficacy and onset time between Tiao Ren An Shen (regulating Conception Vessel and soothing mind) needling method and conventional acupoint selection for peri-menopausal depression, for providing theoretical evidence for the application of Tiao Ren An Shen needling method. Method Sixty patients with peri-menopausal depression aged 45~55 years were randomized into two groups after admission to hospital. In addition to oral administration of Fluoxetine, one group was intervened by Tiao Ren An Shen needling method (treatment group, n=30), and the other group was by conventional acuppoint selection (control group, n=30). Before treatment, and at 2nd, 4th, and 6th week after treatment, Hamilton Depression Scale (HAMD) was investigated, Kupperman index and traditional Chinese medicine (TCM) syndrome score were evaluated before and after intervention. The therapeutic efficacy was estimated at the end of the 6th week. Result After intervention, the HAMD and TCM syndrome score were significantly improved in both groups (P<0.05); Kupperman score was markedly improved in the treatment group (P<0.05), while the score was not significantly changed in the control group (P>0.05). Compared to the control group, the improvements of depression degree and peri-menopausal symptoms were more significant in the treatment group (P<0.05). The total effective rate was 93.3% in the treatment group versus 70.0% in the control group, and the difference was statistically significant (P<0.05). Conclusion Compared to conventional acupoint selection, Tiao Ren An Shen method can produce a more efficient effect and a higher long-term efficacy, not only improving the emotional state and easing depression, but also releasing vegetative nerve functional disturbance. As it can improve the TCM symptoms, treating both causes and manifestations, promoting the quality of life of peri-menopausal patients, this method is an effective approach.

Objective To evaluate the applied value of multislice spiral CT multiplanar reconstruction in diagnosing the trauma oforbit. Methods 40 patients with trauma of orbit underwent multislice spiral CT scan, the thickness of slices was 2 mm and collimator was 0.75 mm. Multiplanar reconstruction (MPR) and free angle parallel ranges reconstruction (PRR) were performed. CT findings of orbital trauma were analysed. The result passes through the surgery and the clinical confirmation.Results 14 cases with radiopaque foreign in orbit comfirmed by operation were accurately localized by MPR and PRR, but 6 cases were misdiagnosed by conventional CT. There were 21 cases with fracture of orbital wall, of them, 9 cases were not detected or partially misdiagnosed by plain CT. The damage of eye musculus rectus was in 16 cases, 6 cases were diagnosed by MPR+PRR. There were 16 cases with eyeball damage, of them , 4 cases detected by conventional CT difficultly, but they identified by MPR and PRR. The damage of optic nerve was in 5 cases, 4 cases were not discovered by conventional CT. Conclusion MPR and PRR are of important value in evaluating the orbital trauma.

?AlM: To observe the changes of corneal topography and astigmatism et al with various duration of closing eyes and sleep;and study the impact of closing eye and sleep causing physiological hypoxia on corneal topography.
? METHODS: Sixteen volunteers were selected ( 32 eyes), 22-33 (26. 19 ± 3. 95) years old, without refractive errors and other eye diseases, as well as never wearing corneal contact lens, including 10 male eyes and 22 female eyes. The main parameters received corneal simulation K value, corneal astigmatism, corneal irregular measure ( ClM ) and the shape factor ( SF ) by Zeiss corneal topographer. They were measured before and after closed eyes 10, 20, 30, 60, 120min; before sleep and after over 6h sleep, they were detected immediately as soon as they opened eyes after 10, 20, 60, 120min.
? RESULTS: During closing eyes, there were no statistical significance on the changes of corneal topography, corneal astigmatism, and SF. After opening eyes and over 6h sleep, there were no statistical significance on the changes of corneal topography, corneal astigmatism, ClM, and SF.
?CONCLUSlON:Closing eyes and sleep don’t injure the cornea substantially, so corneal topography and corneal astigmatism don’t mainly change.