When seen from the practice and development of modern medicine,we are facing challenges from various ethical problems which arise from the progress of life support technique,industry and network technique and its application in medicine,life sciences and electronic sciences.Nowadays,the legislation of medical ethics and regulations have become a heated issue drawing the attention of doctors,pharmacists,laboratorians,nurses,medical information staff,religions personnel,philosophers,medical scientists,and lawyers.This thesis tries to analyses the main ethical problems in the use of medical information so as to justify potential eligible ethical norms in clinical practice,expecting to draw the attention of relevant staff and general public and the fulfillment of ethical norms in the medical practice.

Objective To investigate the application of xingnaojing injections ( XNJI) in inpatients and further provide a reference for the rational drug use. Methods The retrospective investigation was carried out by reviewing 186 hospitalization records with XNJI from a certain hospital from January 2014 to June 2015. The usage, dosage, and indication of XNJI were analyzed. Results Unlabeled use of XNJI was found in the neurology department inpatients. 59. 7% inpatients were treated with overdosed XNJI, and 13. 4% were treated with a single drug dose of 40 mL. The inappropriate solvent selection accounted for 49. 5%. Compatibility of XNJI and western medicine injection accounted for 54. 8%. It was also found that XNJI was used together with potassium chloride in clinic (47. 8%). Conclusion There exist some irrational uses of XNJI in clinic, thus the use and management of traditional Chinese medicine injections should be standarized.

Humans ; Percutaneous Coronary Intervention ; Propensity Score

Animals ; Antioxidants ; metabolism ; Diabetes Mellitus, Experimental ; metabolism ; Melatonin ; metabolism ; Physical Conditioning, Animal ; Rats

Humans ; Infant, Newborn ; Infant, Newborn, Diseases ; Lung Diseases ; Point-of-Care Systems ; Ultrasonography

Objective To design and establish a set of diffusion optical tomography(DOT) system.Methods Near-infrared(NIR) laser was employed as the light source and only one photomultiplier tube(PMT) as the detector.An optical multiplexer was used to alter the detector channels.The 32 channels of the system,which are consisted of 16 launch channels and 16 detector channels,worked under the continuous-wave(CW) model and were used to acquire 256 boundary data.Results Experiments were performed based on the proposed imaging system.The intralipid was used as the tissue-like medium and the India ink as the absorber.Two sets of data on the boundary were sampled,respectively,before and after the absorber was embedded inside the tissue-like medium.The two sets of data were normalized and then used to reconstruct the absorption coefficient distribution.The recovered image reflected the real location and size of the absorber.Conclusion The proposed imaging platform can image the tissue optical parameters effectively.However the resolution of the reconstructed image was not high because the inverse problem was gravely underdetermined and the noise was not considered in the reconstruction algorithm.The recovered result in the next generation system could be improved by making more use of prior information and enhancing the performance of the system.

OBJECTIVE: The aim of this study was to investigate the association of JAK1 polymorphisms with allergic rhinitis in China Han population. METHOD: A total of 450 patients with AR and 615 healthy subjects as control were genotyped for the presence of three single nucleotide polymorphisms using polymerase chain reaction restriction fragment length polymorphism (PGR-RFLP) analysis of DNA extracted from blood samples. RESULT: All control subjects were in Hardy-Weinberg equilibrium, but high frequencies of JAK1 the homozygous rs310241 CC genotype were observed in AR patients compared to controls (P < 0.05). The results also revealed that there was no association between the rest of two investigated SNPs and AR. CONCLUSION Our results suggested that JAK1 gene rs310241 CC genotype was associated with patients with AR.
Asian Continental Ancestry Group ; genetics ; China ; Genetic Predisposition to Disease ; Genotype ; Humans ; Janus Kinase 1 ; genetics ; Polymerase Chain Reaction ; Polymorphism, Restriction Fragment Length ; Polymorphism, Single Nucleotide ; Rhinitis, Allergic ; genetics

Objective To develop a new type of medical ultrasound debridement instrument and the amplitude bar. Methods According to the specific requirements of the debridement instrument, the electronic design techniques were adopted to determine the sound intensity threshold, oscillation amplitude and near-filed distance. Results The amplitude bar could meet all kinds of technical requirements, and the titanium alloy raw materials made it corrosion-resistant and anti-fatigue. Conclusion The amplitude bar adapts well to the debridement instrument, and other medal materials also can be adopted according to different requirements.

The many difficult problems in the course of actual operation are introduced in more than 5 years with governmental centralized procurement of medical equipment. By aiming at specificity of medical equipment that is a relative specialized material and applying existing laws and regulations system, the more scientific and operational solutions are found.

The detection and classification of extracellular action potentials(i.e.spike) of various single neurons from extracellular recordings are crucial for extracting neuronal spike sequences and thereby for investigating the mechanisms of neural information processing in the central nervous system.In order to increase the correctness of spike detecting and sorting,a new analysis algorithm for processing multi-channel spike signals recorded from rat hippocampi with silicon microelectrode arrays is presented.Four recording contacts on the electrode array are arranged close enough to simultaneously record spikes emitted from same neurons.Firstly,the algorithm extracts all spikes in the four channel recordings by using a multi-channel threshold detection method.Secondly,the algorithm classifies the spikes based on a principle component analysis for a specifically designed type of compound spike waveforms.The compound spike waveform is formed by linking four spike waveforms of a same neuronal firing in the four recording channels one by one in series.The test results with both synthetic datasets and experimental recordings reveal that compared with corresponding traditional single-channel algorithm,the multi-channel algorithm can significantly enhance both the number of extracted spikes and the correctness of spike classifications.The algorithm can also increase the number of isolated neurons from a single experimental preparation.These results indicate that the novel method is efficient for the automatic detection and classification of neuronal spikes.