1.Analyses of idea and method in syndrome differentiation and treatment for lung cancer by integrated traditional and western medicine
Jinfeng ZHU ; Yanfen TANG ; Jusong YOU
China Journal of Traditional Chinese Medicine and Pharmacy 2006;0(09):-
According to the causes and pathogenesis of lung cancer in traditional medicine,the principle of syndrome differentiation and treatment,the research achievements of modern medicine,we discuss the idea and method of syndrome differentiation and treatment of lung cancer by integrated traditional and western medicine.We believe the treatment of lung cancer can be taken from several aspects:strengthening body essence and eliminating pathogen;individualized treatment according to the principle of syndrome differentiation and treatment;combining differential symptoms and diagnosis of diseases according to achievements of lung cancer treatment in traditional medicine;choosing suitable treatment by integrated traditional and western medicine considering the different stage of lung cancer.
2.Electrochemical Properties of Sodium Selenite on a Bionic Membrane of Gold Electrode Modified by L-Cysteine Self-assembled Monolayer
Jinfeng WEN ; Aihua ZHU ; Shengyun CUI
Chinese Journal of Analytical Chemistry 2009;37(12):1771-1775
The cyclic voltammetric behaviors of sodium selenite on the gold electrode modified by L-cysteine self-assembled monolayer (L-Syc,Au/SAMs) has been investigated in 0.05 mol/L H_2SO_4 solutions with sodium selenite. Sensitive anodic stripping current of selenium (Se) with the peak potential at 0.99 V (vs. SCE) has been observed. In comparison with the electrochemical properties of sodium selenite on the modified electrode with those on the naked gold electrode, it was found that selenite was reduced to selenium by the redox interaction with sulfur on the monolayer and the monolayer catalytically oxidizes Se as the electrode was positively scanned. According to the electrochemical properties of sodium selenite both on the naked and modified gold electrode, the Se deposition mechanism and catalytic mechanism as well as bionic membrane model were proposed for the bio-utilization of selenite through nano scale selenium.
3.Clinical study on pulmicort respules inhalation in children with acute infectious
Jinfeng WANG ; Jun PENG ; Xueyan ZHU
Chinese Journal of Biochemical Pharmaceutics 2017;37(4):281-283
Objective To discuss the clinical effect of pulmicort respules inhalation in children with acute infectious laryngitis.Methods We selected acute infectious laryngitis in our hospital from November 2015 to November 2016,106 children were divided into two groups,the control group and the observation group of 53 cases,of which the control group of children with conventional treatment,the observation group to take Pulmicort respules inhalation treatment,the two comparison(P<0.05).The total effective rate of the observation group and the control group were 100%and 90.56%respectively(P<0.05).Results The treatment effect of the observation group and the control group were observed and compared(P<0.05),and the improvement of the observation group after treatment and the time of symptom extinction were significantly better than that of the control group(P<0.05); The clinical symptoms of both groups before and after treatment were improved(P<0.05).Conclusion The treatment of children with acute infectious laryngitis by atomizing inhalation of pulmicort respules can obtain obvious therapeutic effect and reduce the adverse reaction caused by improper use of drugs,(fever,cough,wheezing,etc.)have a good improvement in clinical application worthy of recognition.
4.Theoretical foundation and development of core stability training
Chuanfang ZHU ; Qiangmin HUANG ; Jinfeng PENG
Chinese Journal of Tissue Engineering Research 2014;(11):1787-1792
BACKGROUND:Core training has been gradual y accepted worldwide.“Core”is only a generalized perception, and how to define the muscles, the difference among the muscles and the mode of the muscle recruitment consist of the important part of research work on core training.
OBJECTIVE:From the aspects of theoretical basis, the development of training methods and measurement of training effectiveness, to elaborate the method issues and new insights on core stability training.
METHODS:PubMed, ScienceDirect and CNKI databases were searched by the keywords of“core training, core exercise, core strength”in the titles and abstract to retrieve relevant articles published from 1979 to 2013.
RESULTS AND CONCLUSION:The neural subsystem was first reported by Panjabi to monitor the various signals from the transducers and direct the active subsystem to provide the needed stability. Neutral zone is regarded as an important clinical indicator relevant to spinal stability. Spinal injury and muscle weakening can result in spinal instability and even low back pain and peripheral pain. Core trainings include Swiss bal , plank exercise, sling exercise and so on. Up to now, research on core training is focusing on its mechanism. Core stability training is not only defined as torso stability training, but also refined to the stability training of each joint.
5.Relationship between posttraumatic stress symptoms and post-traumatic growth in adolescents
Jinfeng ZHANG ; Zhanbiao SHI ; Zhuohong ZHU
Chinese Journal of Behavioral Medicine and Brain Science 2013;22(8):739-742
Objective To investigate the relationship between post-traumatic stress symptoms and posttraumatic growth among adolescents.Methods In total,1123 junior middle school students sampled from the Wenchuan earthquake area were assessed in june 2011.Questionnaires included the UCLA PTSD Reaction Index for DSM-Ⅳ (Revision 1),Depression Self-Rating Scale for Children (DSRS),the Screen for Child Anxiety Related Emotional Disorders (SCARED),and Post-traumatic Growth Inventory (PTGI).Results The girls reported significantly higher levels of depression (girls 14.72 ± 5.49,boys 13.08 ± 5.83) and anxiety (girls 31.54 ±15.43,boys 27.03 ± 17.09) than boys (P < 0.05).The minorities reported significantly higher levels of PTG (minorities 59.97 ± 14.06,Han 57.71 ± 15.06),PTSD (22.05 ± 12.12,19.42 ± 12.78) and anxiety (30.36 ±16.35,28.01 ± 16.39) than the Han students (P<0.05).The students whose father had higher degree of education reported lower level of depression and higher level of PTG (P < 0.05).Correlation analysis showed that the PTSD total score,avoidance,arousal,DSRS and school avoidance scores were negatively related to PTGI score (r=-0.074,-0.091,-0.075,-0.360,-0.088,P < 0.05).Linear regression analysis showed that the DSRS score was negatively related to PTGI total score and its four sub-scores (β =-0.365,-0.332,-0.332,-0.315,0.284,P < 0.05).Conclusion Depression symptoms is negatively correlated with PTG and may be an adverse factor for post-traumatic growth in adolescents.
6.Dosimetric study of intensity modulated direct aperture optimization radiation therapy for testicular seminoma
Jinfeng ZHU ; Jinghua JIANG ; Yanwen LIU
Chinese Medical Equipment Journal 2017;38(5):103-106
Objective To compare the field-matching techniques and dosimetric characteristics in the target area of testicular seminoma including the abdominal and pelvic cavities between direct aperture optimization intensity modulated radiation therapy (DAO-IMRT) and 3D conformal radiation therapy (3D-CRT),and to analyse the advantages and disadvantages of DAO-IMRT.Methods DAO-IMRT and 3D-CRT plans were designed with Pinnacle treatment planning system for 7 testicular seminoma patients,and the characteristics of both the irradiation methods were analyzed and evaluated by means of the parameters like dose homogeneity indexes,dose volume histograms and etc.Results DAO-IMRT had the hot and cold volumes in the target areas both significantly smaller than those by 3D-CRT,while the conformity index and homogeneity index superior to those by 3D-CRT.The mean doses (Dmean) by DAO-IMRT of the organs at risk (OAR) except the left femur head were all lower than those by 3D-CRT,aud the V15 values of liver,double kidney,small intestine and rectum by DAO-IMRT were statistically lower than those by 3D-CRT (P<0.01).3D-CRT had the V5 values of OAR all lower than those by DAO-IMRT,in which the differences of double kidney,small intestine,bladder,left femur head and normal tissues were significant statistically (P<0.05).The monitor units by DAO-IMRT roughly doubled when compared with those by 3D-CRT,and the difference was also significant (P<0.01).Conclusion DAO-IMRT with easy operation and high reliability can avoid the connection of fields in the target area of testicular seminoma,and is superior to 3D-CRT in dosimetry.
7.Discussion on Errors of Conformal Plumbic Blocks Made with Manual Cutter and Automatic Cutter
Jie CHEN ; Jinfeng ZHU ; Mingdong CHEN
Chinese Medical Equipment Journal 2004;0(09):-
Objective To discuss errors of conformal plumbic blocks made with manual cutter and automatic cutter.Methods According to beam files of Treatment Planning System,the conformal plumbic blocks were made with manual cutter and automatic cutter respectively.Then their errors were measured.Results With manual cutter,the errors of conformal plumbic blocks were 2.355 mm.With automatic cutter,the errors of conformal plumbic blocks were 1.425 mm.Conclusion The errors of conformal plumbic blocks made with automatic cutter are less than the errors of conformal plumbic blocks made with manual cutter,so automatic cutter should be a necessary tool in making conformal plumbic blocks.
8.Analysis of diagnosis and treatment of 750 patients with cervical intraepithelial neoplasia
Shujun CAO ; Ling ZHU ; Jinfeng QIAN ; Daohua YANG ; Xiaoping WAN
Clinical Medicine of China 2011;27(6):563-567
Objective To investigate the diagnosis and treatment of cervical intraepithelial neoplasia and their clinical effect Methods The cases who were diagnosed as CIN through cytology, colposcopy biopsy and histopathological diagnosis were collected from January 2004 to June 2009 in Songjiang Hospital Affiliated to Shanghai Jiaotong University School. Drug therapy, physical therapy, cervical conization and hysterectomy were performed according to the lesion degree of CIN and patients' willingness. Some cases were further treated with surgery, radiotherapy or chemotherapy according to the pathological findings of the initial excision specimens. With long-term follow-up at 6,24 months after the treatment,we performed a comparative analysis on pathological diagnosis and therapeutic effects. Results Seven hundred and fifty cases of CIN were diagnosed after cervical cancer screening,among which,460 cases of CIN Ⅰ ,180 cases of CINⅢⅡ and 110 cases of CIN Ⅲ. Five hundred and Senventy-eight cases received treatment, among which, 46 cases received drug treatment After 6 months, focus disappeared in 32 cases, sustained in 10 cases, upgraded in 2 cases and canceration occurred in 2 cases. 13 cases received physical therapy,no recurrence occured. Four hundred and thirty-five cases received conization treatment, 34 cases with focus upgraded and 4 case recurred after the operation. 84 cases received hysterectomy, of which, 11 cases focus upgraded after the operation and no recurrence. The cases with focus upgraded or recurred all received additional treatment. The effective rate of physical therapy,conization treatment and hysterectomy on all grades of CIN was more than 98% at 2 years, and 69. 7% of drug treatment. The omission diagnostic rate of colposcopy guided biopsy on invasive carcinoma was 2. 2% , and the residual rate of focus of hysterectomy specimens after conization was 16. 2% . Conclusion Colposcopy including multi-point biopsy has high accuracy and specificity in early diagnosis of CIN . Cervical conization is the main method of the treatment of CIN. Patients with CIN Ⅲ and without desire of fertility should consider the removal of the uterus after cervical conization. Drug conservative therapy of CIN should be chosen carefully.
9.Epidemiological survey of high risk factors for cervical intraepithelial neoplasia in women
Shujun CAO ; Jinfeng QIAN ; Ling ZHU ; Xiaoping WAN
Chinese Journal of General Practitioners 2008;7(11):786-787
One hundred and twenty-two patients with confirmed cervical intraepithelial neoplasia (CIN), as a result of occasional screening for uterine cervix cancer in our out-patient clinic between July 2006 and August 2007, and 122 control patients with cervicitis who received colposcopy during the same period were enrolled in this study. Our results showed that 72% participants didn't receive uterine cervix cancer screening during the past 2 years; 55% women had premarital sexual behavior. CIN was most commonly seen in 30 to 34 year old women. Occasional screening could identify 75% CIN. In comparison with the control group, the incidence of earlier first sexual behavior, marriage, and delivery, multiple pregnancy, and frequent abortion was significantly increased in the study group (P < 0.05). We suggest that increased access to uterine cervix cancer screening might be more important than technical improvement.
10.The polymorphism of G+2044A and A-1512C on IL-13 peptide chain among 153 children with asth-ma in Guiyang
Jinfeng ZHANG ; Jun YANG ; Bo LI ; Linghuan ZHANG ; Xiaoping ZHU
Chinese Journal of Microbiology and Immunology 2016;36(2):144-148
Objective To investigate the single nucleotide polymorphisms ( SNP) of IL-13G+2044A and IL-13A-1512C and to analyze their relationships with the occurrence of bronchial asthma in chil-dren in Guiyang city. Methods Sequenom MassArray platform, a newly developed genotyping assay, was used to detect the G+2044A locus and the A-1512C locus in 153 subjects with asthma and 103 healthy sub-jects. Then the results were statistically analyzed with chi-square test and t-test. Results Three genotypes of IL-13G+2044A locus including GG, GA and AA were detected in the subjects with or without asthma. There were significant differences in the genotype distribution between the subjects with or without asthma (χ2 =7. 691, P<0. 05). The subjects carrying the variant allele A at IL-13G+2044A locus were more likely to have asthma than those not harboring the variant allele A. There were significant differences in allele fre-quency between the subjects with or without asthma (χ2 = 7. 458, P<0. 01). Three genotypes of IL-13A-1512C locus including AA, AC and CC were detected in the subjects from both of the two groups. There were significant differences in the genotype distribution between the two groups (χ2 = 12. 906, P<0. 01). The variant allele C at IL-13A-1512C locus was associated with lower risk for asthma. Significant differences in allele frequency were observed the two groups (χ2 =10. 407, P<0. 01). Conclusion Both of the alleles at IL-13G+2044A and IL-13A-1512C loci were associated with asthma. The variant allele A at IL-13G+2044A locus might be the gene predisposing children to asthma in Guiyang city. Children carrying the variant allele C at IL-13A-1512C locus showed a lower risk for asthma in Guiyang city.