1.Early Diagnosis of Placental Abruption
Journal of Medical Research 2006;0(06):-
Objective To evaluate the risk factors,manifestation and utrasonography examination in the diagnosis of placental abruption.Methods The clinical data of 48 patients with placental abruptiontreated in our hospital from Jan. 1999 to Oct. 2006 were analyzed retrospectively. Results Premature delivery rate was 31.25%,the perinatal death rate was 10.42%,choke of neonaty rate was 16.3%,postpartum haemorrhage rate was 14.6%,uterine upoplexy rate was 4.17%,cesarean section rate was 52.1%,ultrasonography diagnosis rate was 28.6%.Conclusions The earlier diagnosis of placental abruption depends on comprehensive analysis risk factors,clinical symptoms and accessory examination such as ultrasonography.
2.Analysis of Cases with Idiopathic Thrombocytopenic Purpura in Pregnancy
Journal of Medical Research 2006;0(04):-
Objective To study the relativity of pregnancy and idiopathic thrombocytopenic purpura(ITP).Method Thirty two pregnancies with ITP from 2000 to 2005 in our hospital were analyzed retrospectively(A group).Eighty feminine inpatients were selected at random and were compared(to include)forty nomal pregnancy delivery(B group)and forty ITP(C group).Results Compared with B group,the ratio of cesarean section,the occurrence of postpartum hemorrhage and time of hospitalization after postpartum of A group was higher.But the mortality of mother and baby and the ratio of choke of neonaty was not sigrificantly different.compared with C group,the number and width of platelet,functing of cruor,and the occurrence of hemorrhage was clearly differentce.Conclusion We think that ITP could effect the functon of cruor of pregnancy,and aggravate the occurrence of hemorrhage of pregnancy. pregnancy didn't affect the course of ITP.
3.Relationship between posttraumatic stress symptoms and post-traumatic growth in adolescents
Jinfeng ZHANG ; Zhanbiao SHI ; Zhuohong ZHU
Chinese Journal of Behavioral Medicine and Brain Science 2013;22(8):739-742
Objective To investigate the relationship between post-traumatic stress symptoms and posttraumatic growth among adolescents.Methods In total,1123 junior middle school students sampled from the Wenchuan earthquake area were assessed in june 2011.Questionnaires included the UCLA PTSD Reaction Index for DSM-Ⅳ (Revision 1),Depression Self-Rating Scale for Children (DSRS),the Screen for Child Anxiety Related Emotional Disorders (SCARED),and Post-traumatic Growth Inventory (PTGI).Results The girls reported significantly higher levels of depression (girls 14.72 ± 5.49,boys 13.08 ± 5.83) and anxiety (girls 31.54 ±15.43,boys 27.03 ± 17.09) than boys (P < 0.05).The minorities reported significantly higher levels of PTG (minorities 59.97 ± 14.06,Han 57.71 ± 15.06),PTSD (22.05 ± 12.12,19.42 ± 12.78) and anxiety (30.36 ±16.35,28.01 ± 16.39) than the Han students (P<0.05).The students whose father had higher degree of education reported lower level of depression and higher level of PTG (P < 0.05).Correlation analysis showed that the PTSD total score,avoidance,arousal,DSRS and school avoidance scores were negatively related to PTGI score (r=-0.074,-0.091,-0.075,-0.360,-0.088,P < 0.05).Linear regression analysis showed that the DSRS score was negatively related to PTGI total score and its four sub-scores (β =-0.365,-0.332,-0.332,-0.315,0.284,P < 0.05).Conclusion Depression symptoms is negatively correlated with PTG and may be an adverse factor for post-traumatic growth in adolescents.
4.In vitro purification of Schwann cells with double negative selection
Jinfeng SHI ; Li LEI ; Yin XIA
Chinese Journal of Tissue Engineering Research 2007;11(33):6697-6700
BACKGROUND: Although cultured technique and purified method of Schwann cells (SCs) are changed successively,purity is still limited. Whether double negative selections can culture high-purified SCs still needs a further study.OBJECTIVE: To investigate the effects of double negative selections on growth and purity of SCs.DESIGN: Controlled animal study.SETTING: Department of Otolaryngology Head and Neck Surgery, Beijing Tongren Hospital, Capital Medical University,and the Beijing Institution of Otolaryngology.MATERIALS: The experiment was carried out in the Department of Otolaryngology Head and Neck Surgery, Beijing Tongren Hospital, Capital Medical University and the Beijing Institution of Otolaryngology between May 2006 and July 2006. Twenty new-born Wistar rats of 3 days (without gender limitation) were provided by the Experimental Animal Center of the Chinese Medical Academy.METHODS: The sciatic nerves of rats were digested by 0.2% collagenase. ① Grouping: All the rats were divided into 4 groups with 5 each. The experimental group was depurated by differential adhesion and Ara-c for 30 minutes. SCs in the control group 1 and 2 were managed by differential adhesion and Ara-c for 30 minutes, respectively. Cells in the control group 3 were not purified. ② Evaluation: The cell growth was observed under invert microscope; growth curves were measured with MTT method in the experimental group and control group 3 to observe cell proliferation. In addition, the SCs were identified by immunocytochemistry; the culture purity was calculated (ratio of S100 positive cells in each sight).MAIN OUTCOME MEASURES: ① Growth of SCs; ② immunocytochemistry stain of SCs; ③ growth curve of SCs; ④ purity of SCs.RESULTS: ① Growth of SCs: At 5 days after incubation, the SCs proliferated well. SCs were spindle, bipolar and sometimes tripolar, with obvious nuclei and a little cytoplasm. There was more fibroblast cell in the group 3 than that in experimental group. ② Growth curve: The SCs in experimental group entered into the logarithm multiplication period at the third day. ③ Immunocytochemistry: The positive-stained SCs were brown in its body and process, and arranged like swirl. The FB with spread and anomaly shape was slight blue. ④ The ratio of anti-S100 positive cells was higher in experimental group than that in group 3 (P < 0.01).CONCLUSION: With the double negative selection, high-purified SCs are obtained effectively.
5.Atypical carcinoid of larynx: a case report.
Wenjing GU ; Xin WANG ; Jinfeng SHI
Journal of Clinical Otorhinolaryngology Head and Neck Surgery 2015;29(17):1565-1567
An 70-year-old male come for swallowing pain 5 years, turning worse 10 months. Laryngoscopy showed a tumor with rough surface at the laryngeal surface of epiglottic. Outpatient pathology: poorly differentiated carcinoma of the larynx. CT: the root of epiglottic is slightly thickened. He accepted the partial laryngectomy, tracheotomy, bilateral functional neck dissection. Pathology: atypical carcinoid of larynx.
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Carcinoid Tumor
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pathology
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Epiglottis
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pathology
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Humans
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Laryngeal Neoplasms
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pathology
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Laryngectomy
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Laryngoscopy
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Larynx
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Neck Dissection
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Tracheotomy
6.The teaching process of surgical nutrition therapy
Bei ZHOU ; Jinfeng ZHENG ; Zhixiu SONG ; Jianhui XUE ; Hongfei SHI
Parenteral & Enteral Nutrition 2017;24(1):52-54
Surgical nutrition therapy is a novel course for undergraduates who are major in food hygiene and nutrition.In this study,the purpose,content,model and specific teaching approaches of the course were discussed,and the essentials of clinical practice for surgical nutrition therapy were pointed out.We hope that our experience would be helpful for the development of the course.
7.Recent advances in basic research, clinical diagnosis and treatment of pancreatic cancer in 2015
Jinfeng XIANG ; Si SHI ; Dingkong LIANG ; Xiangjun YU
China Oncology 2016;26(4):281-289
With the increase of morbidity and mortality, pancreatic cancer will not only become one of the leading causes of death in China, but also a major public health problem in the world. New onset cases of pancreatic cancer all around the world are expected to increase year by year. The prognosis of patients with pancreatic cancer is poor. The 5-year survival rate is only about 6%. The major reason for the poor prognosis is the lack of typical clinical symptoms in the early stage of disease, which makes it difficult to detect and control its relevant recurrence and metastasis. Moreover, lack of effective chemotherapy drugs and resistance to existing chemotherapy drugs are also important reasons for its dismal status. Radical resection surgery is still the most effective treatment. However, even after radical resection surgery, early recurrence and distant metastasis are still the main problems that bother patients. This article reviews recent high quality studies on pancreatic cancer including epidemiological investigation, advances in basic research, and clinical treatment.
8.Therapeutic effect analysis of small bone flap craniotomy decompression of posterior cranial fossa and duraplasty for 45 patients with Chiari malformation type Ⅰ
Guoyuan LING ; Shi YU ; Jinfeng HUANG ; Wendou CHEN
Chinese Journal of Postgraduates of Medicine 2014;37(23):28-30
Objective To evaluate the therapeutic effect of small bone flap craniotomy decompression of posterior cranial fossa and duraplasty in the treatment of Chiari malformation type Ⅰ.Methods The clinical data of 45 Chiari malformation type Ⅰ patients who were treated with small bone flap craniotomy decompression of posterior cranial fossa and duraplasty were retrospectively analyzed,31 cases among them with syringomyelia.Results According to Tator etc.standard,1 month after surgery,the excellent in 30 cases,good in 15 cases.Follow up from 6 months to 6 years,the excellent in 37 cases,good in 8 cases.Among 31 patients with syringomyelia,26 cases were syringomyelia subsided,5 cases were not obvious change.Conclusion The small bone flap craniotomy decompression of posterior cranial fossa and duraplasty can make the craniocervical decompression,and has obvious effect of treating syringomyelia,is safe and effective in treatment of Chiari malformation type Ⅰ.
9.Correlation between spontaneous otoacoustic emissions and transient evoked otoacoustic emissions in neonate
Baoyu SHI ; Jinfeng LIU ; Ningyu WANG ; Fei XIA ; Hui WANG ; Xun WANG ; Jingjing YUAN ; Xin FU
Chinese Archives of Otolaryngology-Head and Neck Surgery 2006;0(01):-
OBJECTIVE The aim of this study is to investigate the correlation between the spontaneous otoacoustic emission(SOAE)and transient evoked otoacoustic emission(TEOAE)in neonate. METHODS The subjects were 224 ears of 112 newborns(59 females, 53 males). The age of subjects ranged from 2 to 4 days (mean?SD: 2.68?0.74 day years). SOAE and TEOAE were measured with ILO96. RESULTS The correlation between SOAE number and TEOAE level were found (r=0.43, P
10.Characteristics of newly reported HIV/AIDS cases aged 15 years and older in Shangcheng District from 2006 to 2022
CHEN Mengqing ; LI Na ; YAO Ying ; HU Jinfeng ; PAN Zhonglian ; SHI Mingming
Journal of Preventive Medicine 2024;36(5):437-439
Objective:
To investigate the characteristics of newly reported HIV/AIDS cases aged 15 years and older in Shangcheng District, Hangzhou City from 2006 to 2022, so as to provide the basis for improving AIDS prevention and control strategies.
Methods:
Data of newly reported HIV/AIDS cases aged 15 years and older in Shangcheng District from 2006 to 2022 were collected through HIV/AIDS Comprehensive Control System of Chinese Disease Prevention and Control Information System. Population distribution and transmission routes were analyzed, and changing trends in case number were analyzed using average annual percent change (AAPC) and annual percent change (APC).
Results:
A total of 4 409 HIV/AIDS cases aged 15 years and older were newly reported in Shangcheng District from 2006 to 2022, including 3 932 males (89.18%). There were 3 447 cases (78.18%) under 50 years old and 962 cases (21.82%) being 50 years and older. Sexual contact was a predominant transmission route, with 4 326 cases accounting for 98.12%, including 2 626 cases (59.56%) with homosexual contact and 1 700 cases (38.56%) with heterosexual contact. The number of HIV/AIDS cases showed an overall upward trend from 2006 to 2022 (AAPC=13.038%, P<0.05), with an upward trend from 2006 to 2015 (APC=42.578%, P<0.05) and a downward trend from 2015 to 2022 (APC=-19.713%, P<0.05). The increase in the number of cases aged 50 years and older group was faster than that of cases aged under 50 years (AAPC=22.641% vs. 11.162%, both P<0.05). The increase in the number of cases with homosexual contact transmission was faster than that of cases with heterosexual contact transmission (AAPC=20.417% vs. 7.455%, both P<0.05).
Conclusions
The number of newly reported HIV/AIDS cases aged 15 years and older in Shangcheng District performed an overall upward trend from 2006 to 2022. The cases aged 50 years and older and transmitted through homosexual contact increased rapidly, which should be taken seriously.