Objective To discuss the occurrence of adverse drug reactions (ADR) induced byDanhong Injection; To provide references for rational clinical medication.Methods Literature related to ADR induced byDanhong Injection was retrieved from CNKI, Wanfang database and CBM database during Jan. 2004 to Dec. 2015. Literature was selected based on inclusion and exclusion criteria. Data were collected and analyzed by metrology.Results 116 cases of ADR induced byDanhong Injection were included. The analysis showed that there was no significant correlation between ADR and gender. Most of ADR cases occurred over the age of 50 and within 30 min after medication. Multiple organs and systems were involved in ADR. Damages in skin tissue, the whole body, and respiratory system were common. Relevant clinical symptoms were mainly itching, skin rash, fever, shiver and shortness of breath. However, anaphylactic shock was needed to be aware of.Conclusion The incidence of ADR induced byDanhong Injection requires great attention in order to standardize medication and improve safety.