Objective To analysis the effect of high filtration rate continuous renal replacement therapy in severe acute pancreatitis pa-tients. Methods According to the admission time,56 severe acute pancreatitis patients were divided into the observation group ( from Jan. 2012 to Mar. 2013,26 cases) and the control group (from Apr. 2010 to Dec. 2011,30 cases). The control group was given CRRT for hemopu-rification while the observation group was given high filtration rate CRRT. The vital signs of rescue period,treatment effect,inflammatory medi-um level,fatality rate and prognosis of the two groups were compared. Results There was no significant change in terms of temperature after operation in the two groups. Pulse and breathing in the observation group were lower than that of the control group with a significant difference (P<0. 05). APACHEⅡ and ALT of the observation group were lower than that of the control group 24 h after the operation,and the differ-ence is of statistical significance(P<0. 05). Conclusion It would get a satisfactory effect to use high filtration rate CRRT in severe acute pancreatitis patients since it can obtain better treatment effect with more stable vital signs, lower inflammatory medium level and lower fatality rate.

Objective To evaluate the teaching effects of micro-lecture based on the wechat platform in new nurses'training in operating rooms.Methods Fifteen new nurses in the operating room in July 2014 were selected as observation group,and thirteen new nurses in July 2013 were selected as control group.The multimedia-aided teaching mode was applied in the two groups,while micro-lecture based on the we-chat platform was implemented in the observation group.The theory and operating skills between two groups were evaluated by examination, and a random inquiry about satisfaction with new nurses was directed on surgeon and seniors nurses.Resulsts 100% of the nurses in obser-vation group accepted and preferred wechat in continuing education.The new nurses’performance in theory and skill test in the observation group was significantly higher than that of the control group (t =2.901,P =0.011;t =2.225,P =0.029).In addition,the surgeon’s and seniors nurses’satisfaction with new nurses in the observation group was significantly higher than that of the control group (Z =6.425,P =0.011).Conclusion Micro-lecture based on the wechat platform can motivate nurses’learning enthusiasm and positivity,and effectively improve their theoretical knowledge and professional skills.