1.Reconstructing thumb opposition function using modified transfer of proper extensor tendon of the fifth digit:5-year follow-up of 21 cases
Jinchang WANG ; Tianbin WANG ; Bingwan LI
Chinese Journal of Tissue Engineering Research 2008;0(53):-
Reconstructing thumb opposition function using modified transfer of proper extensor tendon of the fifth digit is one of the methods to treat old median nerve injury-induced thumb opposition dysfunction.To explore the long-term effect of this method,97 patients undergoing modified transfer of proper extensor tendon of the fifth digit to reconstruct thumb opposition function in Department of Hand Surgery,Affiliated Hospital of Beihua University between January 2003 and December 2007 were retrospectively analyzed,and 21 were followed up.The thumb opposition function postoperatively was evaluated using Changing of Hand Function Evaluation Standard.After reconstructing thumb opposition function,length of thumb (T),distance moving to (mo) and moving away from (Mo) centre of palm in opposition,i.e.during closing and leaving centre of palm distance between middle point of thumb interdigit transverse striation and middle point of middle finger MP joint transverse striation.In addition,their ratios were calculated.The patients were followed-up for 7.5 years (ranging 1-14 years).It is a good therapy to reconstruct thumb opposition function using modified transfer of proper extensor tendon of the fifth digit.
2.Reconstructing thumb opposition function using modified transfer of proper extensor tendon of the fifth digit: 5-year follow-up of 21 cases
Jinchang WANG ; Tianbin WANG ; Bingwan LI
Chinese Journal of Tissue Engineering Research 2009;13(53):10577-10580
Reconstructing thumb opposition function using modified transfer of proper extensor tendon of the fifth digit is one of the methods to treat old median nerve injury-induced thumb opposition dysfunction. To explore the long-term effect of this method, 97 patients undergoing modified transfer of proper extensor tendon of the fifth digit to reconstruct thumb opposition function in Department of Hand Surgery, Affiliated Hospital of Beihua University between January 2003 and December 2007 were retrospectively analyzed, and 21 were followed up. The thumb opposition function postoperatively was evaluated using Changing of Hand Function Evaluation Standard. After reconstructing thumb opposition function, length of thumb (T), distance moving to (mo) and moving away from (Mo) centre of palm in opposition, i.e. during closing and leaving centre of palm distance between middle point of thumb interdigit transverse striation and middle point of middle finger MP joint transverse striation. In addition, their ratios were calculated. The patients were followed-up for 7.5 years (ranging 1-14 years). It is a good therapy to reconstruct thumb opposition function using modified transfer of proper extensor tendon of the fifth digit.
3.Therapeutic Observation of Acupuncture for Malignant Pleural Effusion of Moderate Volume
Bo LI ; Biyu WANG ; Ming YANG ; Jinchang HUANG
Shanghai Journal of Acupuncture and Moxibustion 2016;35(7):823-826
Objective To observe the clinical efficacy of acupuncture in treating malignant pleural effusion (MPE).Method Eighteen MPE patients confirmed by histopathological and/or cytological examinations were treated by acupuncture by selecting Yunmen (LU 2), Qimen (LR 14), Zhangmen (LR 13), Jingmen (GB 25), Guanyuan (CV 4), Zhongji (CV 3), Shuidao (ST 28), and Guilai (ST 29) as the major points. The treatment was given once every other day, 3 times a week, 4 weeks as a treatment course, and the therapeutic efficacy was evaluated 1 course later.Result Of the 18 patients, 6 got complete remission, 9 got partial remission, 2 achieved stable condition, while 1 didn’t respond to the treatment, and the total effective rate was 83.3%. Of the 5 cases with encapsulated pleural effusion, 2 got complete remission and 3 got partial remission, and the total effective rate was 100.0%. The amount of pleural effusion (anteroposterior diameter of the fluid), comprehensive score of symptoms, item scores of the symptoms, and Karnofsky Performance Status (KPS) score were changed significantly after treatment (P<0.01).Conclusion Acupuncture is an effective method in treating MPE of moderate volume, and it can swiftly improve the symptoms and promote the quality of life.
4.Probabilistic safety assessment method in the application of external beam radiotherapy process control management study
Rui HU ; Shi WANG ; Jinchang WU ; Danqing SHEN ; Zhaoxia WU
Chinese Journal of Radiation Oncology 2014;23(5):444-447
Objective To study the probability safety assessment to analyze and evaluate radiation error risk in the external beam radiotherapy,so as to establish and strengthen the control and management of the radiotherapy process,continuous improvement of quality control and quality management.Methods To build the whole of radiotherapy flow chart and process tree,using the decision tree model to determine critical control points in the whole process,making risk assessment chart and analyzing 4 patients with potential safety hazards error.Results The whole process is divided into 22 missions in 3 functional areas,the entire cover 15 branches and 59 key and 11 key control point.The enumeration of error as risks and critical control points has certain correlation.Conclusions Probabilistic safety assessment method have strengthened manage,analyze and control to risk,and all these provide the basis for developing and improving radiotherapy process control management.Radiotherapy quality management for future multidisciplinary and high-level management personnel who take up provides a prospective study.
5.Determination of Phenoxyacetic Acid and 2,4-Dichlorophenoxyacetic Acid Using Solid-phase Extraction and High Performance Liquid Chromatography
Jinchang LI ; Lu WANG ; Mingyou HAN ; Ming BAO ; Guang WANG ; Yuanhong WANG
Chinese Journal of Analytical Chemistry 2001;29(5):580-582
A high performance liquid chromatographic method for the determination of phenoxyacetic acid and 2,4-dichlorophroxyacetic acid in environnmental waters was described.Phenoxyacetic acid and 2, 4-dichioropheroxyacetic acid in sample were enriched on Sep-Pak C18 column,and methanol was employed as elutent.The shim-pack CLC ODS (150mm×6.0mm i.d.) column was used as separation column at 40°C and eluted with methanol-water (9:1,V/V)(pH 3.0) at flow rate of 1.0mL/min,the detection wavelength was 275 nm.The recoveries of the two compounds were>98%.The detection limit was 0.04mg/L.
6.Computed tomography imaging feature of post-intubation tracheal stenosis and its clinical significance
Ke ZHANG ; Ning WEI ; Hao XU ; Maoheng ZU ; Wenliang WANG ; Jinchang XIAO ; Xun WANG
Journal of Interventional Radiology 2014;(5):418-421
Objective To explore the spiral computed tomography (CT) imaging feature of post-intubation tracheal stenosis (PITS) and to discuss its clinical significance. Methods The clinical data and CT imaging findings of 27 patients with PITS were retrospectively analyzed. The location, degree and shape of PITS were analyzed, and the imaging features were summarized. Based on the imaging features the etiology of PITS was suggested, and the role of imaging feature in assessing PITS condition and in planning clinical management was evaluated. Results A total of 35 tracheal strictures were detected in the 27 patients. The location of the strictures included trachea incision site (n=10), balloon level (n=5) and distal end of tube (n = 20). In all patients the degree of stenosis was > 30%. Localized stenosis was seen in 15 cases, which presented as “hourglass”or “girdle”shape. Segmental stenosis was found in 4 cases, which was characterized by a “ribbon” or “dumbbell” stricture on CT scans. Complex stenosis was found in 8 cases. With the help of imaging findings, all patients got timely, proper and individualized treatment. Conclusion PITS has typical imaging characteristics. Spiral CT scanning should be regarded as the imaging examination of first choice. Based on the different imaging characteristics, the relevant departments can evaluate patient’s condition and make individualized treatment plan. The imaging finding is very helpful for anesthesiologists and other clinicians in recognizing and in managing the post-intubation tracheal stenosis.
7.Comprehensive interventional therapy for antiphospholipid syndrome complicated by deep vein thrombosis
Jin LIU ; Ning WEI ; Hao XU ; Maoheng ZU ; Wenliang WANG ; Jinchang XIAO ; Xun WANG
Journal of Interventional Radiology 2014;23(10):874-877
Objective To evaluate the therapeutic results of comprehensive interventional therapy for antiphospholipid syndrome (APS) complicated by deep vein thrombosis (DVT). Methods A total of 10 patients with APS complicated by DVT, who were encountered at authors’ hospital during the period from January 2001 to October 2013, were enrolled in this study. The patients included 3 males and 7 females with a mean age of 45 years (39-74 years). The patients were divided into pure anticoagulantion therapy (group A, n = 4) and catheter-based thrombolysis via the jugular vein combined with anticoagulantion therapy (group B, n = 6). The clinical data were retrospectively analyzed. After the treatment warfarin was orally administered in all patients for at least one year. Results There were no significant differences in general clinical characteristics between the two groups. Before the treatment, the circumference difference of the thighs was (5.55 ± 0.51) cm in group A and was (5.13 ± 0.45) cm in group B. After the treatment, the circumference difference of the thighs was (1.85 ± 0.31) cm in group A and was (0.95 ± 0.26) cm in group B. In both groups, the postoperative calf size was significantly reduced when compared with the preoperative one (both P < 0.01), which was more obvious in group B than in group A (P < 0.05). The detumescence rate in group B was significantly higher than that in group A, which was (81.7 ± 4.1)% vs (67.3 ± 3.6)%(P <0.01). The average hospitalization days of group B and group A were (13.83 ± 0.75) days and (20.75 ± 2.63) days respectively, and the difference was statistically significant (P < 0.05). In group A, clinical effective result was obtained in three patients and ineffective result in one patient, while in group B clinical cure was obtained in all patients. Conclusion In treating APS complicated by DVT, catheter-based thrombolysis via the jugular vein combined with anticoagulantion therapy is safe, effective and time-saving, while pure anticoagulation therapy has only limited efficacy.
8.Ventilatory catheter-assisted airway stenting under local anesthesia for patients with malignant airway stenosis
Ning WEI ; Yufei FU ; Hao XU ; Maoheng ZU ; Wenlang WANG ; Jinchang XIAO ; Xun WANG
Chinese Journal of Radiology 2014;48(11):930-933
Objective To discuss the ventilatory catheter-assisted airway stenting under local anesthesia for airway stenosis.Methods From May 2008 to January 2013,25 consecutive patients with airway stenosis underwent the treatment of ventilatory catheter-assisted airway stenting under local anesthesia.The dyspnea score was grade Ⅱ in 3 patients,grade Ⅲ in 18 patients and grade Ⅳ in 4 patients.During the treatment,a 4 F VER catheter was placed into one of the main bronchi as a ventilatory catheter for oxygen supply in advance,the oxygen flow was set at 2 to 4 L/rmin according to the patients' condition,then the airway stenting was performed,after release of the stent,the ventilatory catheter was removed smoothly.Data on technical success,clinical outcome and follow-up were collected and analyzed respectively.The paired t test was performed to compare variables before and after tracheal stenting.Results Ventilatory catheter-assisted airway stenting under local anesthesia was technically successful in all patients.A total of 25 stents were placed in 25 patients.The stents included I-shaped stents (n=19) and Y-shaped stents (n=6).After the oxygen supply,the patients' SaO2 was increased to 94% to 97% rapidly.When the stent introducer sheaths were passing through the stenotic site,the SaO2 could be maintained at 92% to 97%.The improvement of the respiratory difficulty was achieved in 100% of our patients.The hypoxia symptom was relieved immediately after stents placement,the dyspnea score decreased to grade 0 in 2 patients,to grade Ⅰ in 19 patients and to grade Ⅱ in 4 patients.Respiratory rate and SaO2 improved from (30.0±2.1) times/min and (6.0±3.8)% before stenting to (19.7±1.6) times/min (t=23.33,P<0.01) and (93.0± 1.7)% (t=23.50,P<0.01) after stenting,respectively.Through the follow-up,3 patients suffered the stent-related complications after discharge,the complications included re-stenosis (n=2) and fracture(n=1).Conclusion Ventilatory catheter-assisted airway stenting under local anesthesia can be an effective,simple and safe method for airway stenosis.
9.Treatment of colles fracture with self grasping the horizontal bar style of reduction.
China Journal of Orthopaedics and Traumatology 2008;21(11):841-842
Adolescent
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Adult
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Aged
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Aged, 80 and over
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Colles' Fracture
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therapy
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Exercise Therapy
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Humans
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Musculoskeletal Manipulations
10.Expression of plasma miR-199a-5p and miR-200c-3p and its clinical relevance in gastric carcinoma
Jinli TANG ; Feng YAN ; Xiaoming WANG ; Mengyuan GE ; Zhen GUI ; Jinchang LI ; Mingchen ZHU
Chinese Journal of Laboratory Medicine 2015;(6):402-406
Objective To explore the relative expression of plasma miR-199a-5p and miR-200c-3p in gastric adenocarcinoma cancer(GAC) patients and its clinical value.Methods Case-control study was used in this research.The relative expression of plasma miR-199a-5p and miR-200c-3p from 47 GAC patients and 50 healthy controls were determined by RT-PCR ( TaqMan Probe method).Meanwhile, the association with age, gender, tumor location, size, degree of differentiation, TNM stage, lymph node metastasis and other clinical pathological parameters were analyzed.The expression of these two miRNAs in plasma of 30 GAC patients during preoperation was compared with their expression 6-8 days after radical surgery.The sensitivity and specificity of plasma miRNAs expression for the diagnosis of GAC were analyzed using the receiver operating characteristic ( ROC ) curve.SPSS20.0 statistical software was used for statistical analysis.T-test, paired t-test and one-factor ANOVA were used for normal distribution of quantitative data.Results The plasma level of miR-199a-5p in GAC patients was significantly lower(1.05 ±0.22) (t =3.058,P =0.003), while miR-200c-3p was significantly higher(15.15 ±3.02) (t =-2.854,P=0.006), when they were compared with those in controls(26.80 ±8.38, 3.39 ±0.87).Low miR-199a-5p expression in GAC patients were associated with lymph node metastasis ( F =4.725, P =0.029) and the differentiation degree of gastric cancer(F=3.854,P=0.032).The relative expression of miR-199a-5p in postoperative plasma was significantly increased(t=-3.814,P=0.001), but the relative expression of miR-200c-3p was significantly reduced when compared to the preoperative samples(t=2.978, P=0.006).Area under the ROC curve of miR-199a-5p, miR-200c-3p and combined miR-199a-5p and miR-200c-3p were 0.692, 0.792 and 0.798, the sensitivity and specificity were 87%,97%,92.5% and 43%,54%, 65%, respectively.Conclusion Combined detection of miR-199a-5p and miR-200c-3p in plasma has a higher sensitivity and specificity than the conventional tumor marker CEA and CA19-9, and may be a useful combination for gastric cancer diagnosis.