1.Impact of imaging quality of change pitch on coronary CTA with 64-detector row CT
Xiang LI ; Chaolin JIN ; Shutong ZHANG
Chinese Journal of Radiological Medicine and Protection 2009;29(3):323-325
Objective To investigate the impact of imaging quality of pitch on coronary CT angiography (CTA) with 64-detector row CT. Methods 566 patients were divided into four groups according to heart rate (≤ 50,51-70,71 ~ 80 and ≥ 80 bpm). Three dimensional reconstructions were used such as volume rendering (VR) ,maximum intensity projection(MIP) and curved planar reformation(CPR). Each group was divided into control group and cxperimential group randomly, using normal pitch and revised pitch respectively, and the imaging quality and influencing factons were analyzed among the four groups. Results There was significant difference in imaging quality among the four groups (P < 0.05). Each group had difference in imaging quality with normal pitch and revised pitch. Conclusions The revised pitch helps to improve the imaging quality and meet the demand of diagnosis.
2.The therapeutic effect of Pingyangmycin lipiodol emulsion embolization for hepatic cavernous hemangioma
Heping ZHANG ; Haiying JIN ; Jie ZHANG ; Xiang HE ; Changfu WANG
Chinese Journal of Radiology 2001;0(08):-
Objective To evaluate the therapeutic effect of Pingyangmycin lipiodol emulsion (PLE) embolization for cavernous hemangioma of liver (CHL). Methods Seldinger technique was adopted and the catheter was super-selectively sent into the supplying artery of tumors in 18 CHL patients, 5-10 ml of Lidocaine and 5-20 ml of PLE were slowly injected. Before the embolization, 50-100 mg of pethidine was routinely injected. The embolization was conducted in several times in patients with large tumors, with multiple supplying arteries, and whose age was above 60 years. During the 3-48 months'follow-up after the operation,the change of the tumor diameter before and after the embolization was compared by using CT and ultrasound. The clinical symptomatic relief and the complications were also observed. Results The CHL of all the 18 cases were filled up by PLE. The foci were completely vanished in 9 cases, reduced by over 50% in 7 cases,and reduced by 25%-50% in 2 cases,respectively. The follow-up angiographic examination was performed in six cases, the tumor staining was completely vanished and the tumor-supplying artery was closed up. The improving rate of the clinical symtoms reached 89% . There were no serious complications. Conclusion The PLE embolization in hepatic cavernous hemangioma proves to be reliable, safe, minimally invasive, and with little side effect. This therapy, therefore, can be the first method of choice in treating the cavernous hemangioma of the liver.
4.Generation and Regulation Technology of Stimulating Signals for Implantable Neural Stimulators.
Yan ZHANG ; Jin LI ; Xiang CHEN ; Jianxin WEI
Chinese Journal of Medical Instrumentation 2015;39(3):197-200
The accuracy and robustness of stimulating signals are critical important for implantable neural stimulators since they stimulate neurons directly. The characteristics and applications of stimulating signals were depicted in the paper. The principles and features of five common generation and regulation technology of stimulating signals for implantable neural stimulators were introduced. The technical characteristics of them were analyzed. Finally, the development of the implantable neural simulators was prospected.
Humans
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Implantable Neurostimulators
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Neurons
5.Correlations of 24 biochemical markers in seminal plasma with routine semen parameters.
Hong-ye ZHANG ; Jin-chun LU ; Rui-xiang FENG
National Journal of Andrology 2015;21(12):1087-1092
OBJECTIVETo investigate the correlations of 24 biochemical markers in the seminal plasma with routine semen parameters.
METHODSAccording to the WHO5 standards, we analyzed the routine semen parameters of 66 subfertile men, including the semen volume, sperm concentration, total sperm count, sperm motility, and the percentage of progressively motile sperm (PR). Based on the calibration and quality control measures and using an automatic biochemistry analyzer or electrolyte analyzer, we detected 24 biochemical markers in the seminal plasma of the patients, including total protein (TP), albumin (Alb), globulin (Glb), uric acid (UA), alanine aminotransferase (ALT), aspartate aminotransferase (AST), alkaline phosphatase (AKP), γ-glutamyltransferase (GGT), lactate dehydrogenase (LDH), creatine kinase (CK), alpha hydroxybutyrate dehydrogenase (αHBDH), adenosine deaminase (ADA), glucose (Glu), triglyeride (TG), total cholesterol (TC), urea nitrogen (UN), creatinine (Cr), high-sensitive C-reactive protein (hsCRP), K+, Na+, Cl- , Ca, Mg, and phosphorus (P). Then we analyzed the correlations of the 24 biochemical markers with routine semen parameters.
RESULTSThe levels of the TP, Alb, and Glb proteins in the seminal plasma were positively correlated with sperm concentration, so was that of Alb with the total sperm count, and the AST and LDH activities with sperm concentration and total sperm count. The AKP activity in the seminal plasma was correlated negatively with the semen volume, but positively with sperm motility. The αHBDH activity exhibited a positive correlation with both sperm concentration and total sperm count, with a coefficient of correlation (r) above 0.7. The UN level was correlated negatively with the semen volume, so was the Cr level with the semen volume, sperm concentration, and total sperm count, and the Glu level with sperm concentration and total sperm count. The TG level was correlated positively with the semen volume, but negatively with sperm motility. The levels of seminal plasma ALT, GGT, ADA, UA, TC, CK, and hsCRP showed no correlation with the above-mentioned semen parameters. None of the seminal plasma K+, Na+, Ca, Mg, and P levels was found correlated with semen parameters except the Cl- level, which was negatively correlated with the semen volume.
CONCLUSIONMany biochemical markers in the seminal plasma are closely related to routine semen parameters, indicating that these biochemical components may play roles in spermatogenesis, sperm maturation, and physiological metabolism.
Biomarkers ; chemistry ; Humans ; Male ; Semen ; chemistry ; Semen Analysis ; Sperm Count ; Sperm Motility
6.Value of serum troponin I and creatine kinase isozymes in diagnosis of cardiac muscle impairment induced by acute organic phosphorus pesticide poisoning.
Ling ZHANG ; Xiang-dong JIAN ; Li-yuan JIN
Chinese Journal of Industrial Hygiene and Occupational Diseases 2007;25(7):423-424
Acute Disease
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Adult
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Cardiomyopathies
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blood
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chemically induced
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diagnosis
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Creatine Kinase
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blood
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Female
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Humans
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Male
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Organophosphate Poisoning
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Pesticides
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poisoning
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Troponin I
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blood
7.Clinical study on doxofylline injection in treatment of children with acute asthma attacks.
Jia-xiang ZHANG ; Hui-quan LIN ; Jin-shan CHEN
Chinese Journal of Pediatrics 2004;42(2):143-144
Acute Disease
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Asthma
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drug therapy
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Bronchodilator Agents
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administration & dosage
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adverse effects
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therapeutic use
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Child
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Child, Preschool
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Female
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Humans
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Infant
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Infusions, Intravenous
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Male
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Theophylline
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administration & dosage
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adverse effects
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analogs & derivatives
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therapeutic use
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Treatment Outcome
9.Current situation survey and analysis of a district general hospital in Shanghai
jun, XIANG ; qi-min, HUANG ; jin-fu, ZHANG
Journal of Shanghai Jiaotong University(Medical Science) 2006;0(08):-
Objective To analyse the changes of a district general hospital before and after management by Shanghai Renji Medical Group through current situation survey,and explore the conditions for the development of district general hospitals.Methods The Zhujiajiao People's Hospital of Qingpu District in Shanghai was selected,and patients(n=50)and hospital staff(n=100) were conducted current situation survey with questionnaires which included the knowledge and evaluation of the hospital's current situation as well as the changes before and after management by Shanghai Renji Medical Group.Results Half year after management by Shanghai Renji Medical Group,great progress in medical work was achieved,with a favourable development trend.The rate of satisfaction on medical service evaluated by inpatients reached 89.60%,and 81.91% hospital staff had confidence in the sustainable development of the hospital. Conclusion Management by Shanghai Renji Medical Group has brought prospects for the Zhujiajiao People's Hospital.Under current environment,only certain conditions are met can a district general hospital achieve sustainable development.
10.Construction of a recombinant plasmid pGEX-Sj26GST of Schistosoma japonicum and expression in Escherichia coli BL21 (DE3)
Li, ZHANG ; Wen-gui, LI ; Jin-ping, XIANG
Chinese Journal of Endemiology 2013;32(6):608-611
Objective To construct and express a recombinant plasmid pGEX-Sj26GST of Schistosoma japonicum(Sj) in Escherichia coli(E.coli) BL21 (DE3).Methods Total RNA was extracted from Sj adult worms by RNeasy Mini kit,26 kilodalton glutathione-S-transferases of Schistosomajaponicum (Sj26GST) antigen gene was amplified by real-time PCR(RT-PCR) from the total RNA,then cloned into a prokaryotic expression plasmid pGEX1λT and transformed into E.coli BL21 (DE3) to construct pGEX-Sj26GST; BL21 (pGEX-Sj26GST) was induced with isopropyl-beta-D-thiogalactopyranoside (IPTG),and the expressed products were analyzed and identified by sodium dodecyl sulfate polyacrylamide gel electrophoresis(SDS-PAGE) and Western blotting.Results The 676 bp Sj26GST gene was successfully amplified by RT-PCR and restriction enzyme double-digestion technique confirmed that Sj26GST antigen gene was successfully cloned into pGEX-1λT vector,the relative molecular mass of the expressed recombinant protein was approximately 52 × 103 by SDS-PAGE,and the amount of expressed protein was 20% of the total bacterial proteins; the fusion protein could be recognized by sera from rabbits infected with Sj by Western blotting.Conclusions The recombinant plasmid pGEX-Sj26GST is successfully constructed and highly expressed in E.coli and the expressed fusion protein shows specific antigenicity.