1.Analysis of the related factors of periodontitis in Ningbo petrochemical company staff
Hengbiao PAN ; Hui CHEN ; Dan JIN ; Jing ZHANG
Chinese Journal of Primary Medicine and Pharmacy 2013;20(1):23-25
Objective To find out the prevalence of periodontitis in a petrochemical industry community in Ningbo ; to identify the possible factors of the prevalence; to evaluate the impact of the polluted environment on the oral health of the employees;and to provide information to the enterprises in oral diseases prevention.Methods 2 108 peoples who received regular physical examination in a petrochemical industry community in Ningbo was included.To each subject,a periodontal examination according to the principles and fundamental methods which were used in the third national oral health epidemical survey was carried out,the fast blood was phlebotomized,total cholesterol(TC),triglyceride (TG),uric acid,blood glucose and other serum indexes levels were recorded.These subjects were stratified into two age groups.Data was analyzed with x2 test and multiple regression.Results In the group of 2 108 selected subjects,the periodontitis rate was 52.3 % [95 % CI:(52.3 ± 2.1) %].In the multivariable logistic regression model,the old-age groap age(OR =4.783,P =0.000),blood pressure (OR =1.526,P =0.001) and blood glucose (OR =1.560,P =0.045) were the risk factors of periodontitis,while the environmental factor(OR =0.661) was excluded.In the young and middle-age group,blood pressure (OR =2.184,P =0.000),blood glucose (OR =2.314,P =0.001),TC(OR =1.356,P =0.003),and alcohol (OR =1.382,P =0.02) were the risk factors of periodontitis.Conclusion The levels of blood glucose,TC,blood pressure and alcohol should be considered in periodontitis prevention and the sulfureted hydrogen-based environment factor had no adverse impact on periodontitis.
2.Investigation and application of a diabetes risk score in predicting incident diabetes in male senile people in Beijing
Min LIU ; Changyu PAN ; Hui TIAN ; Mengmeng JIN
Chinese Journal of Endocrinology and Metabolism 2010;26(12):1038-1041
Objective To develop a diabetes risk score (DRS)to predict the risk of development of incident diabetes in male senile people in Beijing. Methods DRS was developed basing on a test group including a cohort of 1 370 individuals aged 48-87 years without diabetes at baseline, followed for 10 years by Logistic regression and validated on a value group including a cohort of 340 individuals aged 43-88 years without diabetes at baseline. Results The model with the highest area under the ROC curve ( AUC ) included age, hypertension,history of hyperglycemia, body mass index, fasting plasma glucose, triglycerides, and high-density lipoproteincholesterol (HDL-C). DRS was developed basing on this model with a range from 0 to 12 and an optimal cut-off of 4. AUC were respectively 0. 726 ( 95% CI0. 692-0. 759 ) and 0. 765 ( 95% CI0. 691-0. 839 ) in test group and validation group. The sum score value ≥4 had sensitivity of 65.3% and 68. 1%, specificity of 70. 0% and 64.8%, positive predictive value of 37.0% and 23.2%, negative predictive value of 88.2% and 94. 1%.Conclusion The DRS, derived from clinical information combined with plasma glucose and lipids, is an effective tool to predict incident diabetes.
3.Effect of Yiqi Huoxue therapy on vascular endothelial growth factor in retina of diabetic rats
Wei YUAN ; Ming JIN ; Lin PAN ; Hui DENG ; Haidan LIU
China Journal of Traditional Chinese Medicine and Pharmacy 2005;0(05):-
0.05).The model group rats displayed high expression of VEGF.Compared with the model group,the expression of VEGF in Yiqi Huoxue medicine group decreased evidently(P
4.Applications of tree-shaped structure in DICOM based on XML.
Chinese Journal of Medical Instrumentation 2006;30(2):83-87
In order to improve the sharing of DICOM, a proposal is offered to introduce XML into DICOM on the SPIE 2005 and in this way, better readability and expansibility of DICOM files have been achieved. On this basis, the DICOM data structure is improved further by replacing the one-dimension linear data structure with multilayer tree-shaped data structure. And thus the nesting and dependence relationships between information object and data elements are much clearer and it is more convenient and easy to browse DICOM image files.
Database Management Systems
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Information Storage and Retrieval
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methods
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standards
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Medical Informatics
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methods
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Medical Records Systems, Computerized
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Programming Languages
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Radiology Information Systems
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Software
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User-Computer Interface
5.Effects of respiratory system elasticity resistance on oxygenation after recruitment maneuvers of ALI patients: a meta-analysis
Chun PAN ; Yingzi HUANG ; Fengmei GUO ; Hui JIN ; Songqiao LIU ; Yi YANG ; Haibo QIU
Chinese Journal of Emergency Medicine 2011;20(4):348-354
Objective To investigate the effects of elasticity resistance (Ers) in respiratory system on oxygenation in patients with acute lung injury (ALI) after recruitment maneuvers (RM). Method Meta-analysis of data about the effects of recruitment maneuvers on oxygenation in ALI patients with different elasticity resistances in respiratory system carried out with pooling of study-oriented data stored in Pubmed, Embase, Web of Science databases from January 1999 to June 2010. Results A total of 281 articles were taken, and 20 of them included a sample size of 395 ALI patients. In patients treated with RM in different degrees of respiratory system elasticity resistance ( ≥33.3 cmH2O/L and <33.3 cmH2O/L), the effect of RM was better in patients with the high respiratory system elasticity resistance than that with the low one [(51.97 + 8.89) mmHg vs. (35.13 ± 10.33 ) mmHg], P < 0. 01 ), but the high respiratory system elasticity resistance was potentially to lower blood pressure [(4. 33 ± 1.32 ) mmHg vs. (0.22 ± 1.03 ) mmHg],P < 0.01 ). Conclusions This study suggests RM could improve oxygenation of ALI patients with high respiratory system elasticity resistance, and caution must be made to avoid hypotension during RM.
6.Meta analysis of transcatheter arterial chemoembolization before hepatectomy for primary hepatocellular carcinoma
Lei YIN ; Zeya PAN ; Bowen WU ; Hui LIU ; Jin ZHANG ; Weiping ZHOU
International Journal of Surgery 2008;35(7):457-460
Objective This study was to systemically evaluate the efficacy of TACE before hepatectomy on resectable primary HCC.Methods The articles focused on preoperative TACE for resectable primary HCC,published from Jan.1,1980 to Jan.1,2008,were selected by computerized search of literatures and manual search of bibliographies.The clinical controlled trials meeting inclusion criteria were reviewed systematically by meta-analysis.The reported data were processed with the statistical techniques of meta analysis.The combinability of the studies was assessed in terms of clinical and statistical criteria.Tumor-free survival rate was calculated.And pooled estimates were computed according to a fixed or random effect model by heterogeneity.Results A total of 1288 patients were included in 8 trials.There was no difference between the two groups in the 1,3-year tumor-free survival rate.Conclusion Preoperative TACE for resectable primary hepatic carcinoma can't improve survival rate.
7.Analysis of ten-year mortality in the male senile population with elevated fasting plasma glucose
Mengmeng JIN ; Changyu PAN ; Hui TIAN ; Min LIU ; Haiyan SU ; Juming LU ; Yiming MU
Chinese Journal of Endocrinology and Metabolism 2008;24(2):157-160
Objective To observe the all-cause and cardiocerebrovascular disease(CCVD)-related mortalities in the senile male population and the relationship of them with fasting plasma glucose (FPG) level.Methods A survey was performed among 1 572 male subjects aged 60-90.All the subjects were groups were calculated by Kaplan-Meier method and the log-rank test was used to compare the survival rates of the 4 groups.Logistic regression model was used to analyze the correlation factors of all-cause mortality and CCVD-related regression model analysis showed that age was related with the all-cause mortality.Among all these factors, age, body mass index, FPG and the history of CCVD had the relationships with the mortality of CCVD.Conclusion In the older male population, CCVD are considered as one of the main causes of death.With the increased levels of FPG, the all-cause mortality and CCVD mortality of senile male population are increased.
8.Effect of oleuropein on IL-1β-induced rat chondrocytes
Bing DAI ; Li XU ; Haidong JIN ; Ningyu CAI ; Hui CHEN ; Bin LI ; Jianwu CAI ; Jun PAN
Chinese Journal of Pathophysiology 2015;(9):1667-1672
AIM:To investigate the effect of oleuropein on interleukin-1β( IL-1β)-induced SD rat articular chondrocytes .METHODS:The SD rat articular chondrocytes were isolated by 2 step enzyme digestions .The chondrocytes were cultured in vitro.Inverted microscopic observation was performed during the culture .Alcian blue staining and type II collagen immunohistochemical staining were used to identify the chondrocytes .The effects of oleuropein on the viability of chondrocytes were determined by CCK-8 assay.The cells in 3rd passage were pretreated with oleuropein at 10, 50 or 100 μmol/L and subsequently stimulated with IL-1βat 10 μg/L for 24 h.Production of prostaglandin E 2 ( PGE2 ) and ni-tric oxide (NO) were evaluated by the Griess reaction and an enzyme linked immunosorbent assay (ELISA).The mRNA expression of matrix metalloproteinase ( MMP)-1 and MMP-13 was measured by real-time PCR.The protein levels of in-ducible nitric oxide synthase (iNOS), cyclooxygenase-2 (COX-2) and nuclear factor-kappa B (NF-κB) were detected by Western blotting .RESULTS:The cell viability of chondrocytes was not significantly impaired by treating with oleuropein at concentration of 10, 50 or 100μmol/L for 24 h compared with control group .Pretreatment with oleuropein significantly in-hibited the production of PGE 2 and NO induced by IL-1β.Oleuropein also significantly decreased the IL-1β-stimulated MMP-1 and MMP-13 mRNA expression in articular chondrocytes .Pretreatment with oleuropein inhibited the IL-1β-media-ted activation of NF-κB by suppressing the degradation of its inhibitory protein IκBαin the cytoplasm .CONCLUSION:Oleuropein inhibits IL-1β-induced inflammatory gene expression by suppressing NF-κB activation at the transcriptional le-vel, suggesting a new mechanism for the anti-inflammatory effects of oleuropein as a novel agent on treating with osteoarthri-tis.
9.Comparative study of intravenous thrombolysis treatment of cardiogenic cerebral infarction and noncardiac cerbral infarction
Weihua DENG ; Yong YANG ; Xiaoping PAN ; Ze LI ; Jin ZHOU ; Hui HUANG ; Haobo CHEN
The Journal of Practical Medicine 2015;(11):1781-1783
Objective To compare the efficacy and safety of intravenous thrombolysis on cardiogenic cerebral infarction and noncardiac infarction by recombinant tissue plasminogen activator (rt-PA). Methods Comparations of NIHSS, mRS and adverse events before and after treatment were made between the cardiogenic group and the noncardiac group. Results No significant differences in the NIHSS and mRS were found between the two groups. The incidence of brain hernia and dermatorrhagia in the cardiogenic group was higher than that in the noncardiac group. Conclusion Rt-PA therapy in cardiogenic cerebral infarction was effective and safe in spite of higher incidence of hemorrhage and brain hernia.
10.Therapeutic effect of endovascular stenting on TIA caused by vascular stenosis
Jin ZHOU ; Weihua DENG ; Hui HUANG ; Yong YANG ; Xiaoping PAN ; Shuda CHEN
Chinese Journal of cardiovascular Rehabilitation Medicine 2015;24(3):270-273
Objective:To explore therapeutic effect and safety of endovascular stenting on transient ischemic attack (TIA) caused by atherosclerotic vascular stenosis .Methods:A total of 100 patients with TIA caused by vascular ste-nosis in our hospital from Jan 2011 to Feb 2013 were enrolled ,and equally divided into combined treatment group (received endovascular stenting combined medication ) and routine treatment group (received medication treat-ment) .After 12-month treatment ,recurrence rate of TIA ,incidence rate of stroke and vascular stenosis rate before and after treatment were compared between two groups .Results:Compared with before treatment ,there was no significant change in all above-stated indexes after treatment in routine treatment group;were significant reduction in vascular restenosis rate [ (73.31 ± 12.76)% vs .(25.01 ± 5.73)% ] in combined treatment group ,and it signifi-cantly reduced than that of routine treatment group (74.33 ± 12.96)% ,P<0.01 both ;during the 12-month follow-up ,compared with routine treatment group , there were significant reductions in percentages of recurrent TIA (16.0% vs .2.0% ) and cerebral stroke (12.0% vs .0) in combined treatment group ,P<0.05 both Conclusion:En-dovascular stenting can significantly improve clinical therapeutic effect and prognosis in patients with atherosclerotic vascular stenosis ,and is worth clinical extension in some condition .