1.Clinical Observation of the Effect Intracervical and Intramuscular Injection of Trichosanthin on Tubal Pregnancy
Chun, LIU ; Xiao'ai LIU ; Yucui, JIN
Journal of Shanghai Jiaotong University(Medical Science) 2000;20(5):447-449
ObjectiveTo evaluate Trichosanthin(TCS) in treating ectopic pregnancy by com-paring to clinical efficacy and side effects between the intramuscular and intracervical adiministrationgroup. MethodsTCS was given to the patients by either the intracervical or the intramuscular route.Compare the clinical results. ResultsThere was a 90% cure rate in the intramuscular injection groupand a 94% cure rate in the intracervical injection group. Side effects were slighter in the intracervical in-jection group than intramuscular injection, especially in fever and its sustained time (P<0.05)。ConclusionsThe clinical efficacy was consistent in two groups but the side effects of the intra - cervicalgroup were slighter.
2.Inhibitory Effect of Jin’s Hemorrhoid Ointment on Human Umbilical Vein Endothelial Cell
Yintong BAO ; Changbao LIU ; Chun JIN
Chinese Journal of Information on Traditional Chinese Medicine 2006;0(07):-
Objective To investigate the inhibition of Jin’s hemorrhoid ointment extract on proliflation of human umbilical vein endothelial cell (ECV-304), then to study the mechanism of treating hemorroid. Methods MTT assay was used to observe the inhibition of various concentrations Jin’s hemorrhoid ointment extract and single Chinese Herbs of compound on human umbilical vein endothelial cell (ECV-304). Results Various concentrations Jin’s hemorrhoid ointment extracts inhibited proliflation of human umbilical vein endothelial cell, which depended on concentration. All of Rheum decoctions and high concetration Curcuma decoction inhibited ECV-304 proliflation. Conclusion Jin’s hemorrhoid ointment can inhibit proliflation of human umbilical vein endothelial cell, and Rheum maybe the main effective part of Jin’s hemorrhoid ointment, Curcuma also take part in it.
4.Analysis and identification of degradation products of buagafuran by high performance liquid chromatography-diode array detection-tandem mass spectrometry.
Xuejun XIA ; Jiuming HE ; Chun LI ; Dujia JIN ; Yuling LIU
Acta Pharmaceutica Sinica 2013;48(8):1292-6
An HPLC-DAD-MS/MS method was developed for rapid analysis and identification of degradation products of buagafuran. Buagafuran and degradation products were separated on a Zorbax C8 column (5 microm, 4.6 mm x 150 mm) using acetonitrile-water (78 : 22) as mobile phase. The elutes were detected with diode array detector and tandem mass spectrometer via electrospray ionization source in positive ion mode. According to analysis of the retention time, UV spectra and MS, MS/MS data, combined with the possible degradation reaction of buagafuran, the structures of main degradation products were inferred. The results showed that six main degradation products were oxidation or peroxidation productions of buagafuran. Degradation product A was a double bond epoxidation product of buagafuran, degradation products B, C, D and E were the further oxidation products of degradation product A, degradation product F was a peroxidation product of buagafuran. The results indicated that the established method was effective in the rapid identification of the degradation products of buagafuran.
5.Anti-inflammation,analgesic and anti-diarrhea effect of volatile oil from A.longiligulare.T.L.Wu
Jin ZHAO ; Zhi DONG ; Yi ZHU ; Guobiao CHEN ; Chun LIU
Chinese Traditional Patent Medicine 1992;0(07):-
0.05).It could also decrease the times of wet manure induced by folia sennae,while it was of no effect on diarrhea induced by castor oil. CONCLUSION: Volatile oil from A.longiligulare T.L.Wu has anti-inflammation,analgesic and anti-diarrhea effect related to the cure for ulcerative colitis.
6.Antioxidative and antinitrosative effects of volatile oil from A.longiligulare T.L.Wu on ulcerative colitis mice
Jin ZHAO ; Yi ZHU ; Zhi DONG ; Guobiao CHEN ; Chun LIU
Chinese Traditional Patent Medicine 1992;0(09):-
AIM: To investigate antioxidative and antinitrosative effects of volatile oil from A.longiligulare T.L.Wu on dextran sulfate sodium(DSS)-induced ulcerative colitis mice. METHODS: Balb/c mice were fed with 4% DSS solution for 7 d to induce ulcerative colitis.Using biochemical method,the activity of antioxidative enzyme SOD,MDA and NO were determined in normal,model,SASP and three mouse's groups with low,moderate and high volatile oil from A.longiligulare T.L.Wu respectively.At the same time,the activity of iNOS was also measured by immunohistopathology. RESULTS: The concentration of MDA and NO were reduced and SOD increased significantly in high-and moderate-volatile oil groups compared with those in the model group.The activity of iNOS was reduced significantly in high-and moderate-volatile oil groups compared with those in the model group.The results demonstrated that the expression of iNOS was significantly inhibited in DSSinduced ulcerative colitis mice after being treated with high or moderate-dosage volatile oil. CONCLUSION: Volatile oil from A.longiligulare T.L.Wu has antioxidative and antinitrosative effects which may be one of the mechanism for treating UC.
7.Rhinocerebral mucormycosis: report of two cases.
Chun-yan HE ; Yu-lan JIN ; Hong-gang LIU
Chinese Journal of Pathology 2010;39(5):345-346
Adolescent
;
Aged
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Aspergillosis
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microbiology
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pathology
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Aspergillus
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isolation & purification
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Brain Diseases
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drug therapy
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microbiology
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pathology
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surgery
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Diabetes Complications
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microbiology
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Diagnosis, Differential
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Female
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Humans
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Male
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Mucorales
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isolation & purification
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Mucormycosis
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drug therapy
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pathology
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surgery
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Nose Diseases
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drug therapy
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microbiology
;
pathology
;
surgery
9.Temperament and Self-esteem of Children Aged 8~12
Ying-chun ZHU ; Sen-yang LANG ; Jin LIU ; Jun YANG
Chinese Journal of Rehabilitation Theory and Practice 2006;12(3):201-202
ObjectiveTo study the level of temperament and self-esteem of children aged 8~12 in Beijing city,as well as their interaction and influenced factor.Methods203 school children aged 8~12 were assessed with Carey's temperament questionnaire(8~12:MCTQ) and The Self-Esteem Scale(SES).ResultsTemperament and self-esteem of school children aged 8~12 were associated with the parental behavior,especially with work style of their fathers.The rhythmicity was found to be negative correlated to the self-esteem scores,and the intensity of reaction was found to be positive correlated to the self-esteem scores.ConclusionParents' behavior and family environment were important to the temperament and self-esteem of school children.
10.Fermentative technology of Soybean Isofiavone Glucoside Hydrolase-Producing Strain
Ming-Jie XIE ; Chun-Hua XU ; Chang-Jiang LIU ; Ming-Chun LU ; Feng-Xie JIN ;
Microbiology 1992;0(03):-
A high active soybean isoflavone glucoside hydrolase-producing mould strain was isolated from spirit qu. Its optimal hydrolase-producing conditions were as follows: 2.5% wheat bran as carbon source, 1% NaNO3 as nitrogen source, initial pH7. 0, culture medium volume 40mL/250mL, inoculating quantity 8% , culture temperature 30℃, revolutions 160r/min and culture time 84h. The enzyme activity reached 82 U/mL. Cu2+ can inhibit Absidia sp. R strain from producing the hydrolase, the influence of other metal ions was not remarkable on it.