1.Liu Qiting’s Experience of Using Yishenjianpihuazhuo Decoction in the Treatment of the Gynecological Disease
Journal of Zhejiang Chinese Medical University 2014;(8):968-969
Objective]We summarized Professor Liu Qiting’s clinical experience of using Yishenjianpihuazhuo Decoction in the treatment of the gynecological disease.[Method] By analyzing the recognition to the causa morbi and mechanism in Liu Qiting ’s treating gynecological disease, this paper summarized the dialectical nursing points of Jianpi Yishen Huazhuo Decoction curing the gynecological disease. [Results] The disease is mostly owing to deficient spleen and kidney, wet heat and toxin accumulated internal y which causes Dai channel uncontrol ed, so the Jianpiyishenhuazhuo Decoction was taken for the treatment of the gynecological disease, with good effect. [Conclusion] Professor Liu Qiting using Jianpi Yishen Huazhuo Decoction in the treatment of gynecological disease has significant implications in the traditional Chinese medicine treatment of gynecological disease.
4.Clinical efficacy of oral mesalazine combined with metronidazole enema in the treatment of patients with ulcerative colitis
Zhiyang HUANG ; Jie JIN ; Liming ZHU ; Fangchao ZHU ; Li SONG
Chinese Journal of Primary Medicine and Pharmacy 2017;24(8):1178-1181
Objective To evaluate the effect of oral mesalazine combined with metronidazole enema in the treatment of patients with ulcerative colitis and the impact on interferon-γ (IFN-γ),interleukin-4 (IL-4),interleukin-8 (IL-8).Methods A total of 80 patients with ulcerative colitis were selected and randomly divided into control group and observation group,40 cases in each group.The control group was treated with oral mesalazine.The observation group was treated with oral mesalazine and metronidazole retention enema.4 weeks as a course of treatment,the patients were treated for 2 courses.The clinical efficacy,disease activity index(DAI) score before and after treatment,as well as peripheral blood erythrocyte sedimentation rate (ESR),levels of IFN-γ,IL-4,IL-8 changes was compared between the two groups.Results The total effective rate was 90.00% in the control group,which was significantly higher than 75.00% in the control group,the difference was statistically significant (x2 =23.52,P < 0.05).Before treatment,there were no significant changes in diarrhea,colonic mucosal inflammation,bloody stool and DAI scores (t =0.32,0.08,0.03,0.05,all P > 0.05).After treatment,there were significant decline in each integral of the two groups,the integral of the observation group declined more than those in the control group,the differences were statistically significant(t =15.35,5.8,11.25,14.12,all P <0.05).Before treatment,there were no significant changes in ESR,IL-4,IL-8,IFN-γ of peripheral blood in the two groups (t =0.60,-0.95,0.03,-0.06,all P > 0.05).After treatment,ESR,IL-8,IFN-γ of peripheral blood declined in the two groups,IL-4 was increased,and the changes were more significantly in the control group than those in the control group(t =10.02,4.70,10.23,22.82,all P < 0.05).Conclusion Oral mesalazine enema combined with metronidazole enema has significant clinical effect in patients with ulcerative colitis,it is better than treating with oral mesalazine only,and can effectively improve the clinical symptoms and possibly plays a role by regulating IL-8,IFN-γ,IL-4,and it deserves further clinical application.
5.Relationship between cognitive fusion and the state of anxiety and depression in perinatal women
Zhihong LI ; Hui ZHU ; Jing CAO ; Meihui JIN ; Zhuohong ZHU
Chinese Journal of Behavioral Medicine and Brain Science 2016;25(5):399-403
Objective To explore the relationship between cognitive fusion and the state of anxiety and depression of perinatal women and to provide empirical evidences for acceptance and commitment therapy in mental treatment of anxiety and depression in perinatal women.Methods 309 perinatal women collected by cluster random sampling were assessed with self-made general information questionnaire,Self-Rating Anxiety Scale (SAS),Self-Rating Depression Scale (SDS) and Cognitive Fusion Questionnaire (CFQ) in predelivcry period and 3-7 days after childbirth respectively.Results (1) CFQ scores in the predelivery or postpartum anxiety group ((32.18±10.78),(31.54±10.30))were higher than that in the normal group((21.49±9.56),(20.84±9.82)),and the difference was statistically significant (t=-8.26,-8.22;all P=0.000);CFQ scores in the predelivery or postpartum depression group ((26.74 ±11.76),(26.84 ± 12.11)) were higher than that in the normal group((23.06± 10.33),(21.79±9.90)),and the difference was statistically significant(t=-2.76,-3.71;P=0.006,0.000).(2)It was found that the predelivery or postpartum CFQ scores were positively associated with the SAS scores of predelivery periods and postpartum periods respectively(r=0.51,0.45,0.50,0.55;P=0.000);the predelivery or postpartum CFQ scores were positively associated with the SDS scores of predelive1y periods and postpartum periods respectively (r =0.26,0.31,0.21,0.38;P =0.000).(3) Hierarchical multiple regression analyses were then conducted.The predelivery CFQ had a significant effect on postpartum SAS(△R 2=0.02,P=0.006)and postpartum SDS respectively(△R 2=0.02,P=0.006),and the regression equations were statistically significant.Conclusion A function to predict the occurrence of matemal postpartum anxiety and depression is obtained from the cognitive fusion which is attributed to the risk of maternal postpartum anxiety and depression.
6.Establishing the System of Academic Assessment and Evaluation on Introduced Talented Personnel
hai-ying, ZHU ; li-jin, CHEN ; xu-ming, ZHU
Journal of Shanghai Jiaotong University(Medical Science) 2006;0(09):-
Objective To evaluate the system of academic assessment and evaluation on introduced talented personnel so as to establish a consummate talented personnel introduction mechanism and to further standardize the introduction work. Methods On the basis of referring to document papers and soliciting management as well as human resource experts iteratively,the research method of expert consultation was adopted.(Results)The index system of academic assessment and evaluation on introduced talented personnel in school of medicine was preliminary established,and the objective index and subjective evaluation were scientifically combined to form the method of academic assessment and evaluation on introduced talented personnel. Conclusion Through simulative assessment and evaluation as well as probational demonstration,there exits definite scientificality and applicability on this academic assessment and evaluation index system,and it can provide a properly objective evaluation and essential reference foundation in the aspect of introducing more advanced talented personnel in the near future.
7.Isolation of Sporothrix from Reed and Soil
Xuezhu JIN ; Fuqiu LI ; Mingji ZHU
Chinese Journal of Dermatology 1994;0(05):-
Objective To study the distribution of Sporothrix in natural environment in Jilin province. Methods Specimens of decayed reed, corn stalks, rotten wood and soil from areas of high incidence rate of sporotricosis (Tongyu county and Nongan county) and low incidence rate (Tumen county) were randomly collected, cultured and subcultured for sporothrix, and the isolates were identified. Results 21 strains of Sporothrix schenckii were isolated and identified. It is the first report that Sporothrix is isolated from corn stalks, rotten wood and soil in our country and is the first report in the world that Sporothrix is isolated from corn stalks. Conclusion The results of study show that there are parasitic Sporothrix schenckii in the reed, corn stalks, rotten wood and soil in the region with high incidence rate of sporotrichosis, and parasitic Sporothrix schenckii in the reed and rotten wood have also been found in the region with low incidence rate. The finding of biological distribution of Sporothrix in the province is of great significance for the prevention and treatment of sporothrichosis.
8.Chemopreventive effects of celecoxib on rat colon aberrant crypt foci induced by dimethylhydrazine
Chinese Journal of Digestion 2001;0(03):-
Objective An investigation was conducted to assess the chemopreventive effects of celecoxib, a selective cyclooxygenase(COX)-2 inhibitor, on a rat colon carcinogenesis model induced by dimethylhydrazine (DMH). The results were compared with those of sulindac. Methods Thirty-two 8-week-old female Sprague-Dawley rats were randomly divided into four groups (n=8 each):Group A rats were treated with DMH(120 mg/kg wt, single subcutaneous injection) alone and group B rats were treated with saline alone. Group C rats were pre-treated with sulindac (320 mg/kg feedstuff) and group D rats pre-treated with celecoxib (1500 mg/kg feedstuff) for 7 days before DMH initiation. The animals were killed at the end of the experiment (week 5) and the aberrant crypt foci(ACF) and aberrant crypt(AC) of the colonic mucosa were assessed after being stained with methylene blue. Results In group A(DMH only), the average numbers of ACF and AC were 182.4?93.43 and 262.8?197.8 respectively. In group B (saline group) rats, no ACF was found. In group C (sulindac group) rats, the average numbers of ACF and AC were 91.25?48.98 and 139.60?68.52 respectively, both of them were decreased significantly as compared with those in Group A (P
9.Epidemiological Characteristics of Japanese Encephalitis in Shanghai
Yanting LI ; Yiyi ZHU ; Bihong JIN
Chinese Journal of Vaccines and Immunization 2008;0(06):-
Objectives To understand the epidemiological characteristics of Japanese Encephalitis in Shanghai and to provide evidence for preventing JE.Methods Epidemic characteristics,JEV antibody in healthy population and swine infection rate in Shanghai were analyzed by methods of field survey,serology and molecular biology.Results JE incident rate in Shanghai was 0.077/100,000 in 2006;and 0.129/100,000 in 2007.Antibody positive rate before JE epidemic fastigium was 60.39%;postive rate after epidemic was 85.44%.JE IgG positive rate was 26.92% in 3-month swine and 14.86% in swine for sale;JE Gene in mosquito was analyzed for type 1.Conclusion The JE prevalence rate is relatively low in Shanghai.JE antibody positive rate is high in Shanghai population.Swine as a media is infected by JE virus.The JE virus in mosquitoes belongs to genotype 1.
10.Clinical significance of the test in serum ammonia concentration in liver cirrhosis with helicobacter pylori infection
Li YANG ; Xiaoling ZHU ; Yonglan JIN
Chinese Journal of Primary Medicine and Pharmacy 2006;0(05):-
Objective To study the relationship between ammonia concentration levels,Child class in cirrhotic patients with helicobacter pylori(Hp) infection and to observe the Hp eradication effect on ammonia.Methods Group A was consisted of 49 cases of cirrhotic patients with Hp infection.Group B included 46 cirrhotic patients without Hp infection.Group C was non-cirrhotic patients with helicobacter pylori infection.Each patient in all three groups was compared with change in serum ammonia concentration before and 4 weeks after Hp eradication therapy.Results The serum ammonia concentration in group A was significantly higher than group B and group C(P0.05).In group A,the serum ammonia concentration was increased as Child classification from A to C(P