No abstract available.

A 24-year old woman presented with hemorrhagic vesicles on her legs. She had taken sibutramine (Reductil(R), Abbott Labs., Seoul, South Korea) for 3 months and developed skin lesions the week before. A skin biopsy showed leukocytoclastic vasculitis with conspicuous eosinophilic infiltration of the tissue. These lesions showed improvement after discontinuation of sibutramine. However, 3 months later the skin lesions recurred on other sites on the lower extremities when the patient was rechallenged with the same drug for 2 weeks. Herein, we report the first case of necrotizing vasculitis induced by sibutramine.
Biopsy ; Cyclobutanes ; Eosinophils ; Female ; Humans ; Leg ; Lower Extremity ; Skin ; Vasculitis ; Vasculitis, Leukocytoclastic, Cutaneous

Epithelioid cell histiocytoma (ECH), also known as epithelioid fibrous histiocytoma, is a rare variant of dermatofibroma, which can mimic melanocytic, vascular, epithelial, or other histiocytic lesions. Although the histogenesis of this condition remains unclear, a recent investigation suggested the possibility that ECH was an angioformative fibrous histiocytoma. There have been no reports of ECH in the Korean literature. Herein, we report a case of ECH in 45-year old man.
Epithelioid Cells* ; Histiocytoma* ; Histiocytoma, Benign Fibrous ; Humans ; Middle Aged

No abstract available.
Cardiac Output* ; Ductus Arteriosus* ; Humans ; Infant, Newborn*

No abstract available.
Female ; Granulosa Cells* ; Interferon-alpha* ; Rodentia*

PURPOSE: The purpose of this study was to examine the effects of parental stress, social support, and coping behavior on burnout among mothers caring for children with cerebral palsy. METHODS: Participants in this cross-sectional, descriptive study were 185 mothers who completed a self-report structured questionnaire. The data were analyzed using descriptive statistics, t-test, one-way ANOVA, correlation and multiple linear regression analyses with IBM SPSS Win 22 program. RESULTS: Parental stress and coping behavior were strong predictors of burnout among mothers of children with cerebral palsy. These variables explained 50.0% of the variance in burnout. Social support was not a predictor of burnout. A higher level of burnout was associated with higher levels of parental stress and lower levels of social support and coping behavior. CONCLUSION: Mothers of children with cerebral palsy are vulnerable to burnout. These results show that effective strategies for reducing parental stress and improving positive coping behavior are needed to reduce burnout in these mothers.
Adaptation, Psychological ; Cerebral Palsy* ; Child* ; Humans ; Linear Models ; Mothers* ; Parenting ; Parents ; Stress, Psychological

BACKGROUND: Epinephrine itself interacts with adrenergic receptors to block pain transmission pathways. Intrathecal co-administration of morphine and epinephrine results in a near maximal increase in the nociceptive threshold. This study was designed to investigate the influence of different dosages of epinephrine on the postoperative pain relief through intrathecal morphine in lower extremity surgery. METHOD: Thirty patients, ASA physical status I or II, undergoing orthopedic surgery of lower extremities were selected and randomly divided into two groups as follows: Group I (n=15); bupivacaine, morphine 0.2 mg with epinephrine 0.12 mg. Group II (n=15); bupivacaine, morphine 0.2 mg with epinephrine 0.2 mg. With patients lateral in the decubitus position, a 25-gauge spinal needle was introduced into the subarachnoid space. Patients were turned to the supine position, and sensory levels were checked by pin-prick tests at the midclavicle level , and the degree of motor block by Bromage scale every 5 minutes. The two segment regression time was measured every 20 minutes. During the postoperative day and the second day, their analgesic effects were evaluated by use of the visual analogous scale (0~10). The side effects were also evaluated. RESULTS: There were no difference between both groups in sensory level and two-segment regression time. Motor block in 5, 10, 15 minutes was more intense in group II. Also, there were no significant difference in the analgesic effects and the incidence of side effects, such as nausea or pruritus. CONCLUSION: There were no significant dose effects of epinephrine added to intrathecal morphine for postoperative pain relief undergoing lower extremities surgery.
Analgesia* ; Bupivacaine ; Epinephrine* ; Humans ; Incidence ; Lower Extremity ; Morphine* ; Nausea ; Needles ; Orthopedics ; Pain, Postoperative ; Pruritus ; Receptors, Adrenergic ; Subarachnoid Space ; Supine Position

No abstract available.

Epinephrine ; Pulmonary Edema

The goals of hip arthroplasty have been to eliminate pain, decrease deformity, increase morbility and obtain stabiIity. Currently total hip replacement is the best avaliable procedure to accomplish these goals. A prospective study of total hip arthroplasty was begun at the orthopedic dept of Kyung Hee Medical College in 1974. Between May, 1974 and June, 1977. 69 total hip replacements of the Charnley type, the Trapesoidal-28 type and the Muller type were peformed by the authors. Of the 60 Patients involved in this study, 9 had bilateral operations. The Charnley type Prosthetic device was used in 56 cases, the Trapesoidal-28 type in 7 cases and the Muller type in 6 cases. Complications included wire breakage, dislocation, loosening, femur shaft perforation, nonunion of greater-trochanter, acetabular protrusion, transient femoral nerve palsy, femur shaft fracture, infection, socket lateralization, ectopic bone formation and death. In 59 patients of the 60 patients, 53 patients felt that they were definitely improved, 5 patients felt their condition was unchanged and 1 patient felt her condition was worse.
Acetabulum ; Arthroplasty ; Arthroplasty, Replacement, Hip ; Clinical Study ; Congenital Abnormalities ; Dislocations ; Femoral Nerve ; Femur ; Hip Prosthesis ; Hip ; Humans ; Orthopedics ; Osteogenesis ; Paralysis ; Prospective Studies