Colorectal cancer is treated primarily by surgery. The goal of surgery is to completely remove the tumor. Surgery for carcinoma of the colon is aimed at removing the tumors with an adequate margin by a wide excision of the tumor-bearing area and associated lymphatics, with attention to the blood supply to the segment and creation of anastomosis without tension. Both rectal and colon cancers are resected for the purpose of cure and prevention of spread and local or pelvic recurrence. The operations generally employed for cancers above the rectum include right colectomy, transverse colectomy, left colectomy, anterior resection, subtotal colectomy, and total colectomy. More limited resections are occasionally performed for palliation in patients with distant metastasis. The survival benefits from the no-touch technique and radical lymphadenectomy with high ligation are still controversial. In rectal cancer, 2 ㎝ is sufficient for the distal resection margin. Several reports have demonstrated improvement in local recurrence rates and cancer-specific survival rate through TME (total mesorectal excision). The technique of chemosensitized irradiation was successful in down staging the tumors and in reducing the tumor size. Preoperative chemoradiation therapy and coloanal anastomosis enables the sphincter-preserving operation more frequently. The rectum, genitourinary structures, and the pelvic autonomic nervous system are very closely related. The urinary and sexual function can be preserved by nerve-sparing operation for rectal cancer. The anorectal function might be improved by colonic pouch operation. Transanal excision or trananal endoscopic microsurgery are advocated for the definitive treatment of small, exophytic, well differentiated, mobile lesions. Resection of hepatic or pulmonary metastasis in cases with-out contraindications improves the survival.
Autonomic Nervous System ; Colectomy ; Colon ; Colonic Neoplasms ; Colorectal Neoplasms* ; Humans ; Ligation ; Lymph Node Excision ; Microsurgery ; Neoplasm Metastasis ; Rectal Neoplasms ; Rectum ; Recurrence ; Survival Rate

No abstract available.
Animals ; Ligation* ; Neuralgia* ; Rats* ; Rhizotomy* ; Spinal Cord* ; Spinal Nerves*

No abstract available.
Coal* ; Mucous Membrane*

No abstract available.
Stomach Neoplasms*

No abstract available.
Cardioplegic Solutions* ; Heart Diseases* ; Heart* ; Hemodynamics* ; Humans

We report a case of tuberculosis verrucosa cutis in a 33-year-old male patient who presented with mild itching verrucous plaque over the perineum. The Mantoux test revealed a positive reaction. The histophathologic picture consists of slight hyperkeratosis, irregular ac:anthosis overlying an inflammatory iafitrate in the dermis. Tuberculous granulomas with caseation necrosis were seen in the dermis. Tuber clebacillus was demonstrated. The patient was treated with Isoniazid, Rifampicin, and Pyrazine made for 6 months. To date, the skin lesions have markedly improved.
Adult ; Dermis ; Granuloma ; Humans ; Isoniazid ; Male ; Necrosis ; Perineum ; Pruritus ; Rifampin ; Skin ; Tuberculosis*

We report the clinical evolution of two elderly male patients with extramammary Paget's disease who were treated with radiotherapy. Both cases primarily involved the scrotum and penile root, and were not associated with any underlying or visceral malignancy. The total doses administered were 6000 cGy and 3000 cGy, respectively. A good clinical response was achieved in both cases. No major side effects were observed. The patients are being followed for any signs of recurrence and have been completely asymptomatic to date
Aged ; Humans ; Male ; Paget Disease, Extramammary ; Radiotherapy* ; Recurrence ; Scrotum

No abstract available.
Evaluation Studies as Topic* ; Hoarseness*

No abstract available.
Adult* ; Doxycycline ; Humans ; Tooth*

Herpes simplex virus infections, with their increasing tendenes are one of the most common infectious diseases. But there have been no systematic investigations on the prevalence of HSV antibodies according to ages in Korea. We therefore decided to investigate this prevalence using micro-neutralization tests. Blood samples were collected from 502 randomly selected men and women, 5 months to 77 years of age who were outpatients or hospitalized patients at the Hanyang University Hospital between 1990-1991. Students at the Hanyang university college of medicine, and other volunteers were also tested. All of the serum samples were assayed for antibodies to HSV useing the microneutralization test. The Cos strain of HSV 1 and the YHS 2-1 strain of HSV 2 were use3 in our study. The antibody titers were expressed as the highest serum dilution causing 80% plaque reduction. The individuals with a neutralizing antibody titer of 1: 2 or higher to HSV 1 were regardel as having the antibody to HSV l. To determine HSV 2 antibody activity, the II/I index was used (II/I mdex : log HSV1 antibody titer/log, HSV 2 antibody titer, lI/I index >0.85) The results obtained were the followings : 1. HSV 1 antibodies were found at a relatively high rate in young a es and its prevalence gradually increased with age. 2. HSV 1 antibody titers iricreased with age. 3. HSV 2 antibodies were not found in children under 11 years of ae but were found in teenagers at a relatively low rate. The prevalence tended to increas with age. 4. HSV 2 antibody titers showed a higher value in those over 31 years of age.
Adolescent ; Antibodies ; Antibodies, Neutralizing ; Child ; Communicable Diseases ; Female ; Herpes Simplex* ; Humans ; Korea ; Male ; Outpatients ; Prevalence* ; Simplexvirus* ; Volunteers