The purpose of this study was to investigate that there was any differences of uptake ratio of Tc99-m-MDP during the healing process related to fracture level in tibia. Thirty mature rabbits were devided into three groups and each group consisted of ten rabbits. The osteotomy was performed at the proximal third of tibia in group I, at the middle third in group II and at the distal third in group III, respectively. After fracture was reduced, the fractured tibia was fixed with K-wire and immobilized with long leg cast. Serial Tc-99m-MDP scintigraphy with pixel counting method was performed in thirty cases of tibial shaft fracture from one day to eight weeks after fracture. The results obtained were as follows: l. In group I, the mean uptake ratio of Tc-99m-MDP at fracture site was 1.40±0.45 at two days after fracture, 3.34±1.21 at two weeks and increased rapidly to a maximal value of 7.51%1.01 at three weeks and decreased thereafter to 4.530.83 at eight weeks. 2. In group II, the mean uptake ratio was 1.10±0.10 at three days, 3.931.±10 at three weeks and increased rapidly to a maximal value of 7.37±2.21 at four weeks and decreased thereafter to 4.54±0.96 at eight weeks. 3. In group III, the mean uptake ratio was 1.13 ± 0.11 at three days, 3.95±0.93 at three weeks and increased rapidly to a maximal value of 7.43±1.72 at four weeks and decreased thereafter to 4.69±0.93 at eight weeks. These experiments suggest that the changes of Tc-99m-MDP scintigraphy in the proximal third fractures of tibia was earlier than middle or distal third fractures and there was no differences between middle and distal third fractures of the tibia.
Leg ; Methods ; Osteotomy ; Rabbits ; Radionuclide Imaging ; Tibia

BACKGROUND: For the diagnoais of atopic dermatitis(AD) an array of basic and minor clinical features proposed by Hanifin and Rajka were in common use. However, there have been some disputes in the diagnostic significance of minor clinical features of AD due to ethni. differences, variance in definitions, materisls and methods, OBJECTIVES: The purpose of the present study was to evaluate the dignostic significance of total 38 minor clinical features of AD in Korean children. Most of them wefe roposed by some authors in the literature and the remainder by ourselves based on our clinical experienes. METHODS: The frequency of these features was studied in 48 patieni s with typical AD compared to that in 89 control subjects. The age of all studied individuals ranged from 2 to 12 years. RESULTS: Thirteen of these was including xerosis, perifollicular acccntuation, frontal lichenification, anterior neck folds, eyelid eczema, Dennie-Morgan folds, auricular fiss are/eczema, pityriasis alba, vertral wrist eczema, infragluteal eczema, sandpaper-like skin lesion of yelbow/knee/lateral malleolus, white dermographism, and scalp scaling were shown to be of mueh diag nostic significance(P<0,001). CONCLUSION: We propose that above-mentioned 13 monor features may be a valuable guideline for the large scale field survey on the incidence and prevalence of AD in Korea children.
Child ; Dermatitis, Atopic* ; Dissent and Disputes ; Eczema ; Eyelids ; Humans ; Incidence ; Korea* ; Neck ; Pityriasis ; Prevalence ; Scalp ; Skin ; Wrist

No abstract available.
Mortality* ; Tuberculosis*

BACKGROUND: Three age-depedent clinical phases(infantile, childhood and adult phase) of atopic dermatitis(AD) were recognized. We think that for t he diagnosis of AD there seems to be some differences in minor clinical features of diagnosic significance according to each phase, yet only a few studies about them. OBJECTIVES: The purprrse of the present study was to evalute the diagnostic significance of total 39 minor clinical features of AD in Korean adolescenc and adult popluation, all but only skin were proposed by our previous study for Korean children. METHODS: The frequeney of 39 minor clinical features wistudied in 82 patients with typical AD compared to that in 109 control subjects. The age all studied individuals ranged from 13 to 42 years. Furthermore, some characteristic micro features of AD in them were compared with those from our previous study for Korean children. RESULTS: Twenty-seven minor features including xerosis, peifolhcular accentuation, frontal lichenification, anterior neck folds, eyelid eczema, Dennie-Mogan folds, auricular fissure/eczema, pityriasis alba, ventiral wrist eczema, infragluteal eczcm, sandpaper-like skin lesions on elbow/knee/lateral malleblus, white dermographism, scalaling, Hertoghes sign, orbital darkening, cheilitis, facial erythema/pallor, hyperlinear paln, ichthyosiform skin lesions, nipple eczema, nummular eczema, pompholyx, itchy hyperker totic lesions of dorsal hands, knuckle dermatitis of hands, hangnail, non-specific hand/foot dermatitis, chronic dermatophytosis were shown to be of much diagnostic signiic, nce(P<0.001). CONCLUSION: We think tiat 13 minor features such as Hert piges sign, cheilitis, facial erythe- mapallor, hyperlinear ichthyosiform skin lesions, ripile eczema, nummular eczema, pompholyx, itchy hyperkpratotic lesions of dorsal hands, kzukle dermatitis of hands, hangnail, non-specific hand/foot dermatitis, chronic dermato h tosis are specific for Korean adolescence and adult population with AD. Taken together, to propose that these 13 minor features be added to a gardeline for the large scale field sirvy on the incidence and prevalence of AD in the Korea adolescence and adult population.
Adolescent* ; Adult* ; Cheilitis ; Child ; Dermatitis ; Dermatitis, Atopic* ; Diagnosis ; Eczema ; Eczema, Dyshidrotic ; Eyelids ; Hand ; Humans ; Incidence ; Korea* ; Neck ; Nipples ; Orbit ; Pityriasis ; Prevalence ; Skin ; Tinea ; Wrist

Recently, intracameral injection of 1% unperserved lidocaine was intro-duced as a supplement to the topical anesthesia in cataract operations. We evaluated the effect of intracameral lidocaine on the corneal endothelium. One hundred eyes of 90 patients undergone scleral tunnel incision and phacoemulsification with posterior chamber intraocular lens implantation were divided into 2 group according to the methods of anesthesia. Topical anesthesia with intracameral injection of 0.2 of 1% unpreserved lidocaine was used to the 50 eyes of 45 patients[group 1] and pinpoint anestesia to the rest[group 2]. Specular microscopy using non-contact specular microscope was done preoperatively, 1 week, 1 month and 3 months postoperatively to compare the endothelial morphologic changes between the 2 groups. The reduction of central corneal endothelial cell density at 3 months postoperatively was 9.45% in Group 1 and 8.74% in Group 2. The difference between the 2 groups was not significant statistically[p>0.1]. Postoperative changes in coefficient of variation[polymegathism] and hexagonality[pleomorphism] were not significantly different between the 2 groups either[p>0.1]. We therefore concluded that intracameral injection of 1% unpreserved lidocaine does not adversely affect the corneal endothelial cell function and morphology and may safely be used as a supplement to topical anesthesia in cataract surgeries.
Anesthesia ; Cataract* ; Endothelial Cells ; Endothelium, Corneal* ; Humans ; Lens Implantation, Intraocular ; Lidocaine* ; Microscopy ; Phacoemulsification

No abstract available.
Myocarditis* ; Stomach*

We measured corneal endothelial cell density of 100 normal eyes of 50 Korean volunteers on central, superior, inferior, nasal and temporal aspect, respectively. Non-contact specular microscopy were used for measurement. The data thus obteined were analyzed according to the following parameters: age, laterality, sex and location(central vs. peripheral). Corneal endothelial cell density showed gradual decrement with age, but no significant statistically differences with laterality and sex. The results showed a large difference in corneal endothelial cell density depending on the location, although they failed to show statistical significant(P>0.05).
Cell Count* ; Endothelial Cells ; Microscopy* ; Volunteers

No abstract available.
Carcinoma, Squamous Cell* ; Cervix Uteri* ; Collagen Type IV* ; Female ; Laminin*

This study was performed ta evaluate difference of colposcopic findings between carcinoma in situ and microinvasive carcinoma. From August l, 1988 through November 30,1989, the conixation was undertaken in 138 patients. We compeied colposcpic findings with hiatologic diagnoiis on 1656 seetions. Comparison between the microinvasive carcinorna and the carcinoma in situ groups showed a significant higher incidence of large exoeervtcal lesion size(>3/2 33.9% vs. 1.2%), circumscribved location around external cervical os.(75.0% vs, 51.2%), combined abnormal colposcopic findings(19.6/a vs. 3. 7%) and deep endocervical involvement( >lcm : 23,2% vs. 7. 3%). (P<0.01) Granular area was showed 11% incidence of the worst histologic diagnosis.
Carcinoma in Situ* ; Cervix Uteri* ; Diagnosis ; Female ; Humans ; Incidence

No abstract available.
Ultrasonography*