No abstract available.

No abstract available.

This study was designed to evaluate the influence of cultured epidermal tissue graft and the administration of transforming growth factor(TGF)-beta3 on maxillary growth in surgically created palatal defects. A total of 155 rats were divided into 2 groups according to surgical timing : postnatal 2 weeks(n=95), 4 weeks(n=40) and control(unoperated) group(n=20). The postnatal 2-week surgical group was subdivided into 3 groups according to repair methods: conventional surgery(Von Langenbeck technique)group(n=23); cultured tissue graft group(n=25); and full thickness skin graft group(n=25). Additionally, recombinant human TGF-beta3 was administered(30ng or 150ng) on collagen matrix in surgically created palatal defects during surgery(9 conventional surgeries, 9 cultured tissue grafts) in 2-week-old rats. The results showed that all types of surgical treatment decreased maxillary growth compared with the control(unoperated) group(p<0.0001). On the other hand, the tissue graft group, whether cultured tissue or grafted skin, contributed to increased maxillary growth(p<0.0001).And exogenous TGF-beta3 might play a role in connective tissue proliferation and new bone generation during wound healing on palatal defects. Our results suggest that grafting cultured epidermis with collagen matrix decreases the scar tension on maxillary growth more than conventional palatal surgery does. Therefore, exogenous TGF-beta3 may contribute to accelerate wound healing on palatal defects.
Animals ; Cicatrix ; Cleft Palate ; Collagen ; Connective Tissue ; Epidermis ; Hand ; Humans ; Rats* ; Skin ; Transforming Growth Factor beta3* ; Transplants* ; Wound Healing

Sparganosis is a rare parasitic infection that can infect the abdominal wall, extremities, urogenital system, and/or central nervous system. Because the incidence of sparganosis is less than 2% of all reported cases of sparganosis, early diagnosis of sparganosis is difficult. Breast sparganosis has characteristic radiologic findings. Complete surgical removal is the treatment of choice and has the benefit of producing a definite diagnosis. Herein, we would report a case of recurrent breast sparganosis that occurred two years after surgical excision of worms from the ipsilateral breast.

Primary retroperitoneal mucinous cystadenocarcinoma is a very rare malignancy. To date, 51 cases have been reported, including 3 in pregnant women. Herein, we report magnetic resonance findings of a 31-year-old Korean woman (15 weeks and 3 days pregnant) with primary retroperitoneal mucinous cystadenocarcinoma. On abdominal magnetic resonance imaging (MRI), a mass was identified in the retroperitoneal area with a nodular lesion showing heterogeneous signal intensity and focal wall thickening on T1- and T2-weighted images. Exploratory laparotomy and tumor excision were performed. Histological examination revealed primary retroperitoneal mucinous cystadenocarcinoma. The patient subsequently underwent total hysterectomy, bilateral salpingo-oophorectomy, and omentectomy for metastatic mucinous cystadenocarcinoma of both ovaries 15 months after her initial surgery.
Adult ; Cystadenocarcinoma, Mucinous ; Female ; Humans ; Hysterectomy ; Laparotomy ; Magnetic Resonance Imaging ; Magnetic Resonance Spectroscopy ; Mucins ; Ovary ; Pregnant Women ; Retroperitoneal Neoplasms